Afore Capital backs product-centric founders at the pre-seed stage exclusively. The investment team brings 16 years of founding product experience (Android and Twitter) and 7 years of institutional investing experience (Founder Collective and Foundation Capital). Their sweet spot is the ~$1M pre-seed round, where they can lead the round as an institutional investor alongside high value angels.

Afore Capital

MuckerLab is a venture capital firm specializing in incubation, pre-seed, seed, startup, early-stage, and Series A investments. It targets investing in Internet software, services, and media ventures. It also prefers to invest in Enterprise, fintech, B2B and Consumer Products.  MuckerLab seeks to invest in Los Angeles and broader Southern California. It typically invests between $0.25 million and $1 million per deal. It runs an accelerator program.  The duration of the program can be as short as 3 months to as long as 24 months. It invests between $21,000 to $150,000 in exchange for a 7% to 12% equity stake.  Erik Rannala and William Hsu founded MuckerLab in October 2011. It has its headquarters in Santa Monica in California.

Mucker Capital

NextGen Venture Partners invests $1-2M in seed-stage companies with the participation of 1,800+ Venture Partners. The firm specializes in the fields of private equity, business strategy, start-up acceleration, and fundraising.

NextGen Venture Partners

Seed firm with ~$140m AUM across two funds. Leading pre-Seed & Seed rounds across the US. We invest U$500k-U$2.5m in companies raising U$500k-U$5m.

ANIMO Ventures

Plug and Play is a seed and early-stage investor focused on great teams leading emerging growth companies.  Plug and Play runs 12 industry-specific accelerator programs twice a year, that acts as a platform for major corporations and high quality startups to connect and collaborate.  Located in the heart of Silicon Valley, Plug and Play participates in Seed, Angel and Series A funding where they often co-invest with their strategic partners. Through years of experience and as part of their network, Plug and Play has put together a world-class network of serial entrepreneurs, strategic investors, and industry leaders who actively assist the firm with its successful and growing investment portfolio.  SEED ROUND. Plug and Play participates in seed round investing through a program called Startup Camp. Startup Camp is a 10-week program based in Silicon Valley for top-notch entrepreneurs to work intensively on building out their business model. Select startups will refine their business models and prototypes with help from a combination of structured workshops, speaker series and mentorship sessions, as well as active coaching from their investment team. At the culmination of Startup Camp, founders will have crystalized their business plans and pitched their company to the venture capital community at EXPO Demo Day.''  ANGEL ROUND Plug and Play makes angel round investments throughout the year, sourced from their monthly Plug and Play Angels (PAPA) sessions. They are partnered with local angel investors in Silicon Valley who participate in PAPA to find the most promising startups and best new technologies.  SERIES A. Series A typical Series A round is in the range of $2 million to $10 million, and is intended to provide operating capital for the company for six months to two years. This round capitalizes the company as it develops its products, performs initial marketing and branding, acquires talent, and conducts other early-stage business operations. It is in this stage that Plug and Play will co-invest with over 180 venture capital partners.  Plug and Play has helped grow market leaders such as PayPal, Danger, Google, DropBox, LendingClub, Zoosk, SoundHound, CreditSesame, Skytree, and has over 400 more early-stage startups in its portfolio.

Plug and Play

AMV is a venture capital firm investing in early-stage digital health, tech, and life sciences companies. The firm has provided early-stage financing for ground-breaking companies such as Amgen, Tandem Computer, and Applied BioSystems. Asset Management was founded in 1965 by venture capitalist Franklin ''Pitch'' Johnson in Palo Alto, California.

Asset Management Ventures (AMV)

Sierra Ventures is a Bay Area-based early-stage venture firm investing globally with a focus on Next Generation Enterprise and Emerging Technologies. With over three decades of experience and over $2 billion of assets under management, Sierra has created a vast network of successful entrepreneurs, Global 1000 CXOs, operational executives, and deep domain experts, providing a platform for entrepreneurs around the world. Sierra Ventures primarily invests in Seed and Series A rounds, with a preference to lead investment rounds and reserve capital for follow on rounds. Investment sectors include artificial intelligence/machine learning, big data, cloud, fintech, health tech, IoT/infrastructure, marketplaces, SaaS & enterprise apps, security, and emerging technologies such as 5G, devices, blockchain, robotics, and virtual reality / augmented reality. Sierra Ventures typically makes initial investments between $500,000 and $7 million on average and invests between $500,000 and $15 million over the life of an investment. The firm has invested in leading companies such as Intuit, Invensense, Greenplum, MakeMyTrip, OnLink, Teradata, StrataCom, Sourcefire, Treasure Data, and more. Sierra Ventures was founded in 1982 and is based in San Mateo, California.

Sierra Ventures

Moore Strategic Ventures is a privately held investment company. It specializes in the fields of financial services, venture capital, and finance.

Moore Strategic Ventures

Venture capital fund investing in digital health and medtech startups to improve health care

NextGen Ventures

Triangle Tweener Fund seeks to create an index of private company investments in their early stages. Its goal is to create an index of Triangle-area early-stage, high-tech startups that meet the 'Tweener List' Criteria.

Triangle Tweener Fund

Pluto Health

Pluto Health develops consumer health technology applications designed to aggregate electronic health record data. The company's application finds, integrates, and automates insights from their medical records and data across different health systems, pharmacies, and labs and also reminds users about tasks such as paying healthcare bills, tracking medications, and sharing health data with providers, empowering patients with tools for better care.

Pluto Health is a smart care coordination service company that offers a platform to address health needs for patients by unifying health information from disparate sources such as insurance, medical, and social determinants. The platform integrates trusted clinical guidelines and supports preventive care. Additionally, Pluto Health helps enhance decision-making and incorporates clinical trials as a potential treatment option for patients.

Traveling Healthcare Assignments on your terms

CRIO Announces Partnership with Pluto Health to Expand and Accelerate Clinical Trial Access

Medable, Pluto Health Strike Enterprise Partnership

Pluto Healthcare Expands Headquarters in the Columbus Region, Creating 65 New Jobs

Grandview Heights, Pluto Healthcare Staffing completing development, incentive agreement

Enabling the health systems to seamlessly connect, exchange, and interpret shared data

Hospital Interoperability

Medable teams up with Pluto Health to simplify, speed trial recruitment

Pluto Health is a smart care coordination service company that offers a platform to address health needs for patients by unifying health information from disparate sources such as insurance, medical, and social determinants. The platform integrates trusted clinical guidelines and supports preventive care. Additionally, Pluto Health helps enhance decision-making and incorporates clinical trials as a potential treatment option for patients.
Key customers and partnerships
In July 2023, Pluto Health announced a partnership with CRIO, a Boston-based healthcare technology company, to develop a scalable integration that enables comprehensive access to preventive health options and better care coordination.
In October 2023, Pluto Health formed an enterprise partnership with Medable Inc., combining their respective platforms to provide patients with greater control and the ability to share their health data directly into clinical trials.

Redox is a leading healthcare technology company that provides a secure and efficient platform for exchanging healthcare data. Its core offering is an integration engine that enables seamless connectivity between various healthcare systems, electronic health records (EHRs), and digital health applications. By acting as a single, standardized API endpoint, Redox simplifies the complex process of interoperability, allowing healthcare organizations to share and access patient data seamlessly.
Redox's platform is built on a standardized data model format, utilizing HTTPS communication with JSON to facilitate secure and convenient integration for healthcare applications. The company's ecosystem encompasses a vast network of over 2,000 healthcare delivery organizations, 350 healthcare software vendors, and connections to more than 90 EHR systems. This extensive reach enables Redox's customers, including payers, providers, and digital health companies, to exchange data with a wide range of healthcare stakeholders.
The company's offerings include Redox Nexus, a managed integration platform that facilitates interoperability between legacy formats and the current FHIR standard; Redox Nova, which enables cloud-based data integration and translation of legacy standards into FHIR; Redox Access, which connects to national clinical networks like Carequality and DirectTrust for seamless clinical data exchange; and Redox Chroma, an Enterprise Master Patient Index (EMPI) solution that aggregates patient records across multiple data sources.
Key customers and partnerships
Redox has established partnerships with leading healthcare organizations and companies, including Mytonomy, a video-based patient engagement company. Mytonomy leverages Redox's integration capabilities to synchronize the assignment and viewership of its educational video modules with health system EHRs, ensuring seamless documentation of patient education activities.
Furthermore, Redox has collaborated with Columbia University Medical Center's Department of Cardiology, enabling the integration of Mytonomy's patient education platform with the center's EHR system.
The company has also forged alliances with healthcare consulting firms like Productive Edge, providing joint solutions for healthcare data integration and strategy development.

Redox

Moxe Health, based in Madison, WI, is a healthcare interoperability company that utilizes innovative technology to simplify and improve the secure exchange of clinical data and crucial insights between healthcare payers and providers. Through its API-enabled solutions compatible with leading electronic health records (EHRs), Moxe fosters meaningful collaboration within the healthcare ecosystem by connecting various stakeholders and facilitating faster, more cost-effective data exchange.
The company's digital release of information (ROI) product automates requests for medical charts, enabling providers to securely fulfill such requests in seconds, eliminating manual processes, paper, faxes, and phone calls. Additionally, Moxe's convergence product allows payers to input their insights directly into the EHR for providers to access. By streamlining data sharing, Moxe empowers providers and payers to optimize operations, improve accuracy, and deliver better financial and clinical outcomes.
As of June 2022, Moxe's network connected major health systems, national health plans representing over 75 million lives, leading third-party requestors, and more than 60 hospital systems. The company aimed to accelerate its mission of advancing interoperability and making healthcare more affordable by eliminating administrative waste through its patient-centric solutions.
Key customers and partnerships
Moxe Health partners with leading healthcare organizations, including Allscripts, whose Allscripts Sunrise EHR users can leverage Moxe's Digital ROI solution for efficient data exchange between health systems, payers, and third-party requestors.

Moxe Health

Particle Health is a developer-friendly API platform that aggregates and standardizes data from over 270 million patients' medical records across thousands of healthcare sources in the US. The company's comprehensive API enables healthcare providers and digital health companies to easily obtain clinical data points and actionable patient health insights through a single integration. Particle Health's technology performs patient matching behind the scenes to connect accounts within HIPAA authorization, overcoming the challenges of accessing medical records across different portals and providers.
Since its inception, Particle Health has achieved significant milestones, including a 90% success rate in finding patient records and an average of 105 records per patient search as of July 2022. The company has expanded its offering beyond electronic medical records (EMRs) to include data sources such as pharmacy records, admission, discharge, and transfer (ADT) notifications, and billing claims data, with plans to integrate genomics and other sources in the future.
Key customers and partnerships
Particle Health has formed notable partnerships and collaborations with various healthcare companies and organizations. For instance, xCures, a technology platform that uses artificial intelligence and predictive modeling to identify and rank treatment options for cancer patients, has integrated Particle Health's Specialty Search capabilities. This integration allows xCures to efficiently access comprehensive oncology data, leading to a significant increase in program enrollment and better patient care management.
Another strategic partnership was announced in November 2023 between Particle Health and Hona, a customizable AI product that converts health records into concise patient overviews. By integrating Particle Health's API for medical record retrieval, Hona can analyze and present a complete view of a patient's health history, enabling providers to make informed clinical decisions and streamline care encounters.

Particle Health

Verto Health is a Canadian digital health company that offers a Digital Twin Orchestration Platform. Its patented machine learning technology consolidates data from various sources to create normalized, contextual snapshots – known as 'Digital Twins' – of each patient's healthcare journey. Verto's platform then automates actions across different systems while securely managing consent, data, and communication.
In October 2022, Unity Health Toronto implemented Verto's technology to help manage ambulatory patient flow, streamline consent management, and transform patient experience across dozens of ambulatory clinics. Verto's solution allowed Unity Health to coordinate and engage with patients before, during, after, and in-between hospital visits, supporting care pathway management and enhancing the patient experience.
Key customers and partnerships
In July 2023, Verto Health partnered with the Centre for Addiction and Mental Health (CAMH) to develop a web-based Digital Front Door platform. This platform aimed to digitize the patient journey and support data-driven, measurement-based care for CAMH's patients and care providers. The collaboration involved co-designing, configuring, and implementing the Digital Front Door to act as a single-point of entry for CAMH patients and families, enabling virtual care and integrating various patient-facing information systems.

Verto Health

Wellsheet is the leading provider of a Smart Electronic Health Record (EHR) User Interface (UI) solution that aims to reduce clinician burnout and increase efficiency and usability of EHRs. The company's technology utilizes artificial intelligence (AI) and machine learning algorithms to synthesize, summarize, and elevate relevant clinical data from EHRs like Cerner, Epic, or athenahealth, as well as other data sources.Wellsheet's Smart EHR UI predicts and prioritizes the most pertinent data based on a clinician's specialty and workflow habits, assembling it in an intuitive and customizable manner. This enables providers to quickly arrive at accurate clinical insights without compromising patient interactions. By embedding within existing EHRs, the solution helps clinicians understand what needs to be done and make more informed decisions while reducing errors.As of July 2022, Wellsheet had an enterprise-wide deployment with over 10,000 clinicians using its interface, reducing the time spent in EHRs for physicians, nurses, and care managers. The company's FHIR-based APIs allow for rapid implementation across multiple data sources within weeks and minimal training requirements.

Wellsheet

Includes tools that allow healthcare providers to aggregate clinical data (both structured and unstructured) from a variety of sources and share this information with other providers, patients, or insurance providers.

Platforms that provide interoperability APIs and developer toolkits that allow siloed healthcare applications or systems to communicate with each other. Targeted at both healthcare providers and digital health apps.

Software platforms that integrate patient information (including social determinants of health) from multiple sources to digital tools. These tools support patient management and offer actionable insights on a patient's health by leveraging data analytics.

Healthcare data is exchanged, shared, and interpreted via digital mediums

AI/ML algorithms aggregate and standardize data for seamless sharing between healthcare systems

IoT technology is being used to improve hospital interoperability, connectivity, and secure data sharing

Incorporating technology to improve efficiency and success rate of clinical trials

Clinical Trial Technology

Clinical trial management software provider, Medable, has partnered with healthcare coordination company, Pluto Health, to enhance the clinical trial experience for participants and improve data collection. Through this collaboration, patients will be connected to the appropriate medical resources, including access to clinical trials and home delivery of medication. Pluto Health's platform will collect health information and create personalized care plans for participants, while Medable will provide features such as patient identification and remote patient monitoring. The partnership aims to improve data quality and enable long-term follow-up with patients after the trial. Pluto Health offers an automated care coordination platform that assists patients in addressing their health needs and care gaps, and claims to have closed over 500,000 care gaps as of September 2023.

Pluto Health

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