Manulife Financial

New York Life Insurance

Established renewable energy technologies for a greener future

Current-gen renewables

<div>
 
 Canadian Solar Inc. (Nasdaq: CSIQ) is a leading global manufacturer of solar photovoltaic modules and provider of solar energy solutions. Founded in 2001 by Dr. Shawn Qu in Ontario, Canada, the company has grown to become one of the top solar panel producers worldwide, with a presence in over 160 countries and employing more than 13,500 people globally.
 
 
 
 
 Canadian Solar offers a diverse range of solar panels and energy storage solutions for various applications, including residential, commercial, and utility-scale projects. The company's product line encompasses solar modules with outputs ranging from 300 to 600 watts and efficiencies between 19% and 21.3%. Canadian Solar also manufactures bifacial modules capable of generating up to 30% more energy by capturing light from both sides.
 
 
 
 
 One of Canadian Solar's strengths lies in its excellent performance in low-light conditions, ensuring consistent energy production even on cloudy days or during winter months. The company's solar panels meet international quality and safety standards, offering reliable performance at competitive prices. Canadian Solar has an extensive global production footprint with 20 manufacturing facilities across Asia and the Americas.
 
 
 
 
 As of 2023, Canadian Solar has developed more than 55 gigawatts (GW) of solar energy projects worldwide, cementing its position as a leading utility-scale solar PV project developer. The company has an impressive pipeline of 23.8 GW of solar projects and 27.5 GWh of energy storage projects under development.
 
 
 
 
 In 2024, Canadian Solar was recognized with the Top Brand PV Award US for its excellence in the renewable energy industry, underscoring its strong reputation and the trust it has built among customers and business partners globally.
 
 
 
 
 Key customers and partnerships
 
 
 
 
 
 Canadian Solar has established partnerships and delivered solar energy solutions to customers across various industries and regions worldwide. The company's diverse customer base spans residential, commercial, and utility-scale sectors, solidifying its position as a trusted provider of solar power solutions.
 
 
 
 
 In 2024, Canadian Solar expanded its joint venture partnership with BrightNight, surpassing their initial targets. The joint venture now encompasses a portfolio of 30 projects with a combined capacity of over 18 GW across nine states in the US, including the Box Canyon site in Pinal County, Arizona.
 
</div>

Silfab Solar is a North American leader in the design, development, and manufacturing of high-efficiency, premium-quality photovoltaic (PV) solar modules. The company leverages over 40 years of experience in the solar industry and utilizes state-of-the-art automation, precision engineering, and rigorous quality control measures to produce durable, reliable, and high-performing solar panels specifically designed for the North American market.
Silfab offers a range of residential, commercial, and utility-scale solar module series, including the Elite Series, Prime Series, and Commercial Series. The Elite Series panels, manufactured exclusively in the US, boast the highest efficiency ratings, with innovative back-contact technology and integrated cell design to maximize light capture and conversion. The Prime Series caters to homeowners seeking high-quality, aesthetically pleasing panels, while the Commercial Series targets large-scale projects requiring maximum power density.
The company's solar modules are rated among the top performers by industry organizations like PVEL and EnergySage, with efficiency ratings ranging from 19.2% to 21.4%. Silfab's panels are engineered to withstand harsh North American weather conditions, including extreme temperatures, wind, and hail, with certifications for wind load resistance up to 5400 Pa and hail impact resistance up to one inch at 51.6 mph.
In March 2023, Silfab announced plans to open a third US manufacturing facility in 2024, with an initial annual capacity of one gigawatt for solar cell production and 1.2 gigawatts for module assembly. This expansion was supported by a USD 125 million investment from ARC Financial Corp.'s Energy Fund nine and co-investors, enabling Silfab to further strengthen its domestic supply chain and accelerate its US manufacturing strategy.

Membership-based, non-insurance healthcare companies helping maintain a steady state of well being.

Preventive Healthcare

juli is an AI-driven chronic care management platform that gathers biomarker data to identify triggers of difficult-to-treat chronic conditions and provides recommendations requiring micro behavioral changes. It gathers data from smartphones and wearables, environmental data, and electronic health records as well as patient-reported information specific to the condition. It combines and analyzes this data with AI and machine learning to give insights and recommendations to improve health. As of March 2022, the company had served nearly 15,000 patients via the juli app. The company covers chronic conditions such as asthma, depression, migraine, bipolar disorder, and chronic pain.The app uses both a passive and active approach to gathering information. Its AI gathers information passively from wearables while individuals can also actively provide information on their specific condition. Additionally, the app generates patterns and possible correlations between an individual’s disease and lifestyle.The company was selected by the US Department of Health and Human Services as one of 15 digital health startups to join the 2022 PandemicX Accelerator cohort and one of the companies selected into SoftBank Vision Fund’s Emerge Program for 2021. juli operates a B2C and B2B2C business model and is free for use. The company may introduce a subscription model in both markets for additional services in the future.

More important now than ever, telehealth will long outlast the pandemic that drove its growth.

Telehealth

League is a Canadian patient engagement platform offering personalized solutions to healthcare organizations. Its application programming interface (API) platform and technology infrastructure allow healthcare providers, payers, employers, and consumer health practitioners to build personalized digital experiences for their patients. Additionally, its health OS (operating system) platform provides a customizable digital front door solution that supports patient triage and helps increase patient engagement. The company claims its customers can build and deploy healthcare experiences within six months.The health OS platform was developed using the Fast Healthcare Interoperability Resources technology and leverages the Google Cloud Platform Healthcare API to collate patient health data from multiple sources, including electronic health records (EHRs), medical claims, wearable devices, and third-party partnerships to tailor patient experiences.League announced in <a href="https://www.prnewswire.com/news-releases/league-brings-generative-ai-to-digital-member-and-patient-experience-with-google-cloud-301950717.html#:~:text=LAS%20VEGAS%2C%20Oct.,consumer%20experience%20personalization%20at%20scale.">October 2023</a> that the company would use Google Cloud's Generative AI capabilities for greater customer experience and personalization capabilities on its platform, with an initial focus on optimizing member and patient journey orchestration.Key customers and partnershipsMost recently in <a href="https://sp-edge.com/updates/35063">October 2024</a>, League partnered with Medibank, an Australian private health insurer, to provide a more personalized healthcare experience for Medibank's customers. As a part of the partnership, League's data and AI-driven technology were integrated into Medibank's digital capabilities.In <a href="https://www.mobihealthnews.com/news/highmark-health-google-cloud-league-partner-build-digital-front-door#:~:text=Earlier%20this%20year%2C%20League%20and,a%20healthcare%20consumer%20experience%20platform.">November 2022</a>, the company announced it would work with healthcare provider Highmark Health and Google Cloud to develop a digital health platform for Highmark members.In <a href="https://www.businesswire.com/news/home/20220322005816/en/League-Announces-Collaboration-with-Google-Cloud">March 2022</a>, the company announced a strategic partnership with Google Cloud to improve patient engagement and offer a customized experience to its B2B clients using Google Cloud’s application programming interface (API).

A concentration of wealth and a willingness to adopt age-in-place technologies present new opportunities.

Age Tech

GetSetUp provides a digital platform that connects retired, re-skilled educators with other seniors for live, online lessons on a variety of topics. The platform offers over 500 classes across 18 topic categories, some of which are aging in place, communication, cooking, financial planning, languages, and technology. In addition, the platform has a rotating list of featured series for events for seniors such as women’s health week, preventing fraud and scams, and how to start a business. Additionally, the company allows users to host their own sessions in order to share their knowledge with communities. GetSetUp also has a club feature, allowing users to form groups and social circles for individuals sharing similar interests, helping seniors to have social interactions with other users.The platform operates on a subscription basis, offering both individual plans and community plans for a monthly or annual fee.Key customers and partnershipsGetSetUp has partnered with several entities to either help seniors develop new skills or expand the platform’s reach. Some of these partnerships are as follows:GetSetUp partnered with the Michigan Department of Health and Human Services in <a href="https://www.prnewswire.com/news-releases/getsetup-partners-with-michigan-department-of-health-and-human-services-to-make-its-interactive-learning-platform-accessible-to-2-5-million-older-adults-301156096.html">October 2020 </a>to make its platform accessible to 2.5 million seniors who are registered with the Department.The company also partnered with Uber in <a href="https://www.prnewswire.com/news-releases/uber-partners-with-getsetup-to-teach-older-adults-to-use-ubers-services-and-apps-301392429.html#:~:text=In%2DLanguage%20News-,Uber%20partners%20with%20GetSetUp%20to%20teach%20older%20adults%20to%20use,increase%20mobility%20for%20older%20adults.">October 2021 </a>to teach older adults to use Uber's services and apps. Through the partnership, GetSetUp offered free classes during the pilot and to teach seniors how to navigate the Uber app.The New York State Office for the Aging (NYSOFA) and Association on Aging in New York (AgingNY) expanded its partnership with GetSetUp in <a href="https://aging.ny.gov/news/nysofa-agingny-and-getsetup-expand-partnership-offering-free-online-classes-hundreds-thousands">October 2022 </a>to continue offering free online classes for hundreds of thousands of older adults in New York State. The company then partnered with the New Jersey Department of Human Resources in <a href="https://www.nj.gov/humanservices/news/pressreleases/2022/approved/20221117c.shtml">November 2022 </a>to offer free online courses for older adults.More recently, GetSetUp expanded its partnership with the Michigan Department of Health and Human Services (MDHHS) in <a href="https://www.michigan.gov/mdhhs/inside-mdhhs/newsroom/2023/08/21/getsetup-extension">August 2023 </a>. Through the expansion, Michigan residents aged 50 and older were given access to an additional 500,000 free virtual classes across a range of topics.

The latest line of defense against rising cyber attacks

Cyber Insurance

Embroker offers commercial insurance for startups, law firms, and other private companies. It covers incidents such as commercial crime, professional liabilities, and cyber insurance. Policies issued by Embroker are underwritten using data-driven models that it claims can reduce premiums for businesses by 20%.Embroker’s cyber insurance product helps companies cover against both first- and third-party financial losses resulting from cyberattacks. These include costs relating to data loss, recovery, business interruption, extortion, and fraud. Embroker also offers technological errors and omissions (E&amp;O) for technology companies. Policies issued by Embroker are backed by Clear Blue Specialty Insurance Company (reinsured by MunichRe) and as of December 2021, the company served over 20,000 users; counting companies such as Icebreaker Health, Pandia Health, Renew Energy Partners, JDJ Engineering among its clients.Key customers and partnershipsEmbroker <a href="https://sp-edge.com/updates/20434">announced partnerships </a>with cyber insurer Cowbell and password management platform Dashlane in July 2023. Cowbell’s admitted insurance product will be bundled with Embroker’s lawyer’s professional liability (LPL) offering, while Dashlane will be made available to Embroker customers at a discount.Funding and financialsDuring Q1 2021, the company surpassed USD 20 million in gross written premium and experienced a customer retention rate of 100%.The company raised USD 100 million in Series C funding in June 2021 led by FTV Capital. The company expected to use the funding to transition into a full-stack insurance carrier.

Platforms, apps, and cards to keep the corporate wallet in check

Business Expense Management

<div>
 
 Procurify is a Canadian company offering a cloud-based business payout and expense card management platform for SMBs. The payout management solution (dubbed Procurify Spend Management Platform) covers purchase workflows, budget tracking, and spend analytics and covers the entire procurement process from purchase orders and matching invoices to approvals and making payments (one-off and recurring). The platform can be used for cross-border vendor payments as well.
 
 
 Procurify launched its business expense card solution in January 2022 (both physical and virtual cards). The cards also provide real-time spend insights and visibility and are offered as a free add-on to its spend management platform. 
 
 
 The platform automates expense tracking and reporting by integrating with various financial software providers, including QuickBooks, NetSuite, and Amazon Business PunchOut. Procurify offers several packages for its users, which vary based on features such as financial software integrations, API access, and number of domains. 
 
 
 Key customers and partnerships
 
 
 The company has SMB customers across over 70 countries. Its customers include Goodwill Industries, Samumed, Asana, the University of Maryland, and Goop.
 
 
 In February 2024, 
 <a href="https://sp-edge.com/updates/26780">
 Procurify partnered with Veriscape
 </a>
 , a supply chain technology provider, to introduce real-time spend visibility and control.
 
 
 Funding and financials
 
 
 <a href="https://sp-edge.com/updates/22785">
 In October 2023,
 </a>
 raised USD 50 million in a Series C funding round led by Ten Coves Capital to expand globally, launch new payment capabilities, and enhance the AI-powered procure-to-pay experience for customers.
 
 
 As of January 2022, the platform managed over USD 18 billion in annual organizational spending. The company reportedly generated annual revenues of around USD 5.5 million as of July 2019, at which point it managed around USD 7 billion in annual spending. 
 
</div>

Enabling the health systems to seamlessly connect, exchange, and interpret shared data

Hospital Interoperability

League is a platform technology company that provides a healthcare consumer experience (CX) platform called Health OS. Founded in 2014, League enables payers, providers, consumer health partners, and employers to build and deploy personalized digital healthcare applications and experiences for consumers. The company's platform is built on the Fast healthcare Interoperability Resources (FHIR) standard and leverages the Google Cloud Platform (GCP) healthcare API to serve as a "digital front door" to healthcare services for millions of consumers.
League's Health OS platform consolidates data from various sources, including electronic health records (EHRs), claims, health and wellness devices, and third-party partners, to deliver personalized digital health experiences and create a cohesive, omnichannel experience for consumers. The platform empowers stakeholders across the healthcare continuum to develop and deploy next-generation applications with a secure, reliable, and interoperable foundation.
Among League's notable customers are organizations such as Humana, Shopify, Shoppers Drug Mart, and Highmark Health. In November 2022, League collaborated with Highmark Health and Google Cloud to unveil an interoperable digital health platform that simplifies navigation and access to healthcare services for Highmark's 6.8 million members through a new "My Highmark" member portal and mobile application.
Key customers and partnerships
In May 2023, League announced a partnership with Publicis Health, a global leader in healthcare communications, to enable better and more connected patient experiences by combining League's healthcare CX platform with Publicis Health's marketing insights and engagement design capabilities.
League has also collaborated with Accenture to create personalized digital healthcare experiences and increase access to healthcare services for people, providers, payers, and retail pharmacies. The companies are working together with Shoppers Drug Mart to expand the capabilities of its PC Health platform.
Additionally, League has partnered with Google Cloud to leverage its technology and enable successful digital transformation in healthcare.

AI, robotics, and IoT to streamline the flow of goods and information

Logistics Tech

Canada-based Procurify offers a cloud-based purchasing management platform that supports the end-to-end procurement process from the creation of purchase orders and matching invoices to approvals and making payments. Procurify's modules cover purchase order management, vendor relationship building, streamlined receiving, insightful reporting, integrations with ERP and accounting systems, and&nbsp;<a href="https://sp-edge.com/updates/35445">accounts payable automation.</a>&nbsp;Procurify follows a subscription-based SaaS model.As of August 2023, the platform managed over USD 30 billion in annual organizational spending. The company reportedly generated annual revenues of around USD 5.5 million as of July 2019, at which point it managed around USD 7 billion in annual spending.Key customers and partnershipsProcurify has 100+ customers globally as of April 2024. Its customers include HyperFiber, Block Energy, Community Youth Ministries, Texas Rocket Engineering Lab, SkipTheDishes, Vow, Cabify, Atlantech, Inari Medical, and Proudfoot.&nbsp;The platform offers integrations with financial software such as QuickBooks, NetSuite, and Amazon Business PunchOut. <a href="https://sp-edge.com/updates/23467">In October 2023, </a>the company also partnered with Olive Technologies, a provider of AI-based decision-making solutions, to introduce streamlined and innovative processes in vendor sourcing and procurement.&nbsp;

Simplifying healthcare administration with intuitive tech tools

Hospital Management

League is a platform technology company founded in 2014 that powers next-generation healthcare consumer experiences. The company's Health OS platform serves as a secure, reliable, and interoperable foundation for stakeholders across the healthcare continuum, including payers, providers, consumer health partners, and employers. League's platform enables these organizations to build and deploy applications that transform healthcare from disparate point solutions into a cohesive, omnichannel experience for consumers.
Built on the Fast healthcare Interoperability Resources (FHIR) standard, League's Health OS leverages Google Cloud's healthcare API to connect patient health information from electronic health records, claims, wearable devices, and third-party partners. This integration delivers deeply personalized digital health experiences tailored to individual consumer needs. The platform facilitates access to care navigation, virtual health services, bill payment, cost transparency, and other functionalities through a unified interface.
League has established partnerships with major healthcare organizations, including Humana, Shopify, and Loblaw Companies (Shoppers Drug Mart). In January 2023, League collaborated with Highmark Health and Google Cloud to unveil the My Highmark digital health platform, providing Highmark's 6.8 million members with a seamless, personalized care experience through a single sign-on application.
As of September 2022, League secured over USD 205 million in funding, with a USD 95 million Series C round led by TDM Growth Partners and participation from Workday Ventures. The company aims to position its Health OS as the leading digital infrastructure for an integrated healthcare ecosystem, facilitating innovation, interoperability, and economies of scale across the industry.

Simplifying the insurance experience for businesses using technology

InsurTech: Commercial Lines

<div>
 
 Embroker offers a range of insurance products, including directors and officers insurance, employment practices liability, cyber, professional liability, and more. Its digital platform allows businesses to obtain quotes, manage policies, and handle claims online. The company uses predictive, data-driven underwriting models to automate underwriting and improve the accuracy of risk assessment. It claims that its algorithmic-based risk management reduces premiums for businesses by up to 20%.&nbsp;
 
 
 
 
 
 Key customers and partnerships&nbsp;
 
 
 Embroker specifically catered to funded startups, tech companies, law firms, and consultants and served over 40,000 customers as of May 2024.&nbsp;
 
 
 In July 2023, the company announced strategic partnerships with Dashlane, a security-first password management provider, and Cowbell, a cyber insurance provider for SMEs. Embroker aimed to enhance customer security using Dashlane&rsquo;s cyber protection services and expand its cyber liability offering by providing Cowbell Cyber Insurance to existing and prospective customers.&nbsp;
 
 
 In November 2023, the company entered into a strategic partnership with Ascend, a provider of financial operations automation software for insurers. Through this partnership, Embroker aimed to leverage Ascend&rsquo;s technological capabilities to improve operational efficiency and optimize its risk management process.
 
 
 
</div>

Waterlily makes long-term care planning easy. Using AI trained on over 500 million data points, Waterlily predicts an individual's personalized likelihood of needing long-term care later in life, projects the exact cost of their long-term care and even calculates the number of hours that each member of their family will step in to provide caregiving. The software then guides families through building a holistic plan consisting of financial planning, care planning, and the logistics of family coordination.

TELL is on a mission to revolutionize the fight against neurodegenerative diseases like Alzheimer's, Parkinson's, and frontotemporal dementia. The company's innovative approach to brain health combines automated speech and language analysis with cutting-edge AI technology to detect early markers and provide reliable data to get to diagnoses. The company's HIPAA-compliant SaaS solution is designed to address the challenges of early detection, specificity, cost, access, and reliability. By offering a unified, user-friendly, and scalable tool for discovering and implementing novel markers, we're bringing hope to patients, caregivers, and healthcare professionals across the globe. So, whether you're a patient, physician, biotech company, health insurance provider, or government agency, TELL is here to help you make better decisions and improve brain health for all.

Zencey's platform is a one-stop destination to help patients manage their health. They use our virtual medical assistant to evaluate their symptoms and get personalized guidance on the most adequate care option for their situation. If necessary, they can connect with one of our doctors and specialists for an online consultation at their convenience. We also offer flexible and affordable employee health coverage plans for small businesses.

Givers supports and pays family caregivers.

Smplicare is building a digital platform to bring peace of mind that your ageing loved ones are living safe, healthy and independent lives at home for longer.

Addition Wealth is a holistic financial wellness platform that empowers employees to make smart, informed financial decisions. By taking a tech-forward approach that combines digital tools, online events, expert content, and access to financial professionals, Addition is making personalized financial expertise inclusive and accessible for all employees. Addition partners with forward-thinking employers to help employees make the most of their money.

Dedicated to your health. We're a digital healthcare startup on a worldwide mission to improve the lives of people with chronic conditions. We're really good at analyzing data and want to use this superpower to change healthcare for the better. There’s great potential within all the health data we're all already collecting about ourselves. We at juli strive to bring it all together! juli was founded in 2020, right at the start of the COVID-19 pandemic by a group of people that wanted to use their knowledge about big data for a better cause. Some of the founders suffer from a chronic condition themselves and have been on the lookout for many years to find out what triggers episodes and what helps to get better.  Learn more

GetSetUp is an online platform and community that helps older adults enjoy more fulfilling, independent, and socially connected lives through learning. GetSetUp offers on-demand, engaging learning experiences that range from teaching everyday technical skills to enrichment-focused courses taught by passionate instructors.

Conquest Planning is a FinTech company that is developing an innovative solution for the financial services industry.

Spearmint aims to be the preeminent green merchant trading company developing, owning, operating, and trading around Battery Energy Storage, Solar, and Wind to reduce grid volatility, increase system resiliency, and help to reduce Carbon emissions in a responsible and efficient way.

Silfab Solar is the North American leader in the design, development, and manufacture of ultra-high-efficiency, premium quality PV modules. Silfab leverages 40 years of solar experience and best-in-class technologies to produce the highest-rated solar modules from facilities in the state of Washington and Toronto, Canada. Each facility features multiple automated ISO 9001-2015 quality certified production lines utilizing just-in-time manufacturing to deliver Buy American approved PV modules specifically designed for and dedicated to the North American market.

EVN Finance is an integrated financial institution. They offer financial goods and services to businesses in the energy sector and other economic sectors. Their products include those for financial institutions, enterprises, individuals, and consumers.

FreshBooks is changing the way business owners manage their books. Its owner-first accounting platform, loved by businesses in over 160 countries, takes an easy-to-use approach to manage finances, billing, payments, and client engagement.  FreshBooks, known for its 10x Stevie award-winning customer support, serves customers of all sizes from offices in Canada, Croatia, Mexico, Netherlands, and the US.

Vestwell develops a digital savings platform to create a retirement plan for employees. It offers automated retirement investing options for RIAs depending on the rules and regulations and other defined contributions to companies and their employees to help advisers engage with their clients with compliance and automation.

MindBeacon features one of the most comprehensive digital Therapist-Assisted Guided iCBT therapy packages available. Its TAiCBT can cure a wide range of mental health issues, from stress to sleep problems, anxiety to alcoholism, panic to PTSD. Because many of these issues are interconnected, the clients' journey through the program is constantly adjusted by their devoted therapist, and each client receives a customized treatment plan tailored to their specific needs.

Procurify is a cloud-based procurement tool that helps businesses manage their spending. The company's platform enables businesses to access centralized purchasing management, custom approvals, budget controls, and insights to help fuel business growth, while also providing complete control and visibility of where company money is going and accountability for your entire organization.

Embroker is the easiest way to intelligently ensure any business. By pairing technology and broker expertise, Embroker helps growing businesses save time and find the best value on the right coverage. As the leading digital insurance brokerage, Embroker is working to massively improve the $800 billion property and casualty (P&C) insurance market. Headquartered in San Francisco, we have offices in Chicago and Boston and customers in all 50 states.

NextCapital partners with world-class institutions to deliver personalized planning and managed accounts to individual investors across multiple channels including 401(k), IRA, and taxable brokerage accounts. Their open-architecture digital advice solution provides integrated account aggregation, analytics, planning, and portfolio management, and allows partners to customize advice methodology and fiduciary roles. The company was founded in 1996 and headquartered in Chicago, Illinois.

Figure 1 connects healthcare professionals around the world to view, discuss, and share medical cases. It now has a global community of millions of healthcare professionals. It was founded in 2012 and is headquartered in Toronto, Canada.

League is a platform technology company powering next-generation healthcare consumer experiences.

Canadian Solar is a solar power company that manufactures and sells solar cell and module products that convert sunlight into electricity for a variety of uses. Canadian Solar designs, manufactures, and sells a wide range of solar energy products, including solar modules, solar system kits, and solar power plants. They provide solar solutions for residential, commercial, and industrial customers, as well as utility-scale power projects. The company's solar modules are widely used in various applications, including grid-tied solar power plants, off-grid systems, and residential rooftop installations. In addition to manufacturing solar modules, Canadian Solar is also involved in the development and operation of solar power projects. They develop and build solar power plants globally, contributing to the expansion of renewable energy infrastructure.

Element Fleet Management is a fleet management company that provides world-class management services and financing for commercial vehicle and equipment fleets.

Invenergy is a privately-held developer and operator of sustainable energy solutions. It has developed nearly 150 projects, including wind, solar, and natural gas power generation as well as advanced energy storage facilities.

PTC Therapeutics, Inc., a biopharmaceutical company, engages in the discovery, development, and commercialization of orally administered and small-molecule drugs. It offers Ataluren, an orally administered small-molecule investigational new drug for the treatment of cystic fibrosis and duchenne muscular dystrophy caused by nonsense mutations. The company also provides PTC299, an anti-angiogenesis drug for the treatment of metastatic breast cancer, multiple tumors, and neurofibromatosis. Its products are used for the treatment of genetic disorders, oncology, and infectious diseases. PTC Therapeutics, Inc. was founded in 1998 and is based in South Plainfield, New Jersey.

Manulife Financial is a Canada-based financial services company with principal operations in Asia, Canada and the United States. Since welcoming its first customers in 1887, Manulife Financial has built a significant global presence by providing customers with strong, reliable, trustworthy and forward-thinking solutions for their most significant financial decisions. Manulife Financial international network of more than 84,000 employees and agents offers our clients a broad range of financial protection and wealth management products and services. We offer personal, commercial, corporate and investment banking products to millions of customers across our three operating divisions: Asia, Canada and the United States, each of which represents about one third of our overall business. Manulife Financial has a demonstrated business expertise in Asia dating back more than 100 years. Since issuing our first Asian policy in Shanghai in 1897, we have pursued strong, sustained growth and remained a leading provider of financial protection and wealth management products in Asia. We are relentlessly focused on helping Asian customers prepare for their future, and that focus drives our growth strategy and underpins our commitment to the region. Now diversified across Asia, including some of the world’s largest and fastest-growing economies, we have deep roots and an expanded operational footprint across all of this important region. We have more than 50,000 contracted agents selling our products and have expanded our distribution capabilities to include more than 100 bank partnerships and more than 500 dealers, independent agents and brokers. Learn more about our operations in Asia.

<div> Manulife Financial (NYSE: MFC) is a Canadian multinational insurance company and financial services provider. It has been trading on the Toronto (TSX), New York (NYSE), Philippines (PSE), and Hong Kong (SEHK)&nbsp;stock exchanges, respectively, since 1999. The company operates as &quot;Manulife&quot; in Canada and Asia and through its John Hancock Financial division in the US and is the largest insurance company in Canada (December 2021). Manulife earned total gross premiums (GPs) of CAD 44.1 billion (~USD 34 billion) and generated a total revenue of CAD 17.1 billion (USD 13.1 billion) in 2022. The company&rsquo;s insurance (and insurance-based wealth accumulation) business is categorized into Life and Health Insurance and Annuities and Pension business lines. The Life and Health Insurance business offers a range of health, life, travel, combination, and mortgage protection insurance products. The Annuities and Pension business includes insurance-based wealth and asset management solutions for individuals, groups, and institutions. Additionally, Manulife provides non-insurance-based investment advice and innovative solutions to retirement, retail, and institutional clients through its Global Wealth and Asset Management segment.&nbsp; Asia was Manulife&rsquo;s largest market, accounting for ~51% of GWP in 2022, followed by Canada (~28%) and the US (~21%). Manulife&rsquo;s strategic priorities include accelerating growth through 2025 to generate 75% of core earnings from the companies&rsquo; highest potential businesses and 50% from Asia. The company is committed to reaching the net-zero status by 2050. </div>

Reinsurance Group announces $4.1B coinsurance transaction with Manulife Financial

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