We invest in companies taking transformational approaches to address significant unmet needs within healthcare.

Rhythm VC

Y Combinator is a startup accelerator that invests in a large number of startups twice a year. It created a new model for funding startups. Twice a year, the company invests a small amount of money ($150k) in a large number of startups. The startup accelerator works intensively with the companies for three months, to get them into the best possible shape and refine their pitch to investors. Each cycle culminates in Demo Day when the startups present their companies to a carefully selected, invite-only audience.

Y Combinator

Hoxton Ventures focuses on startups that either disrupt existing industries or invent entirely new market categories. Hoxton typically invests between $500,000 and $5 million into pre-seed, seed, and Series A stage companies, and follows its capital through the life of the company.  The firm is based in London and invests all across Europe.

Hoxton Ventures

Route 66 Ventures is a private investment firm focused on helping entrepreneurs shape the financial services landscape of tomorrow by providing Venture Capital and Credit solutions to emerging financial technology and services companies.   Route 66’s Venture Capital team invests globally in early and growth stage disruptors, incumbents and service providers throughout various sectors in the financial services ecosystem.   Route 66’s Credit team seeks to fund alternative lending platforms and business models with balance sheet needs by purchasing whole loans or providing secured debt facilities.

Route 66 Ventures

Octopus Ventures is a venture capital firm that offers support to companies at various stages of their journey, from idea conception to IPO. They allocate over £200 million annually to invest in sectors such as health, fintech, deep tech, consumer, and B2B software, with a focus on making a positive impact. Their experienced team assists portfolio companies in scaling rapidly. Octopus Ventures' investment philosophy extends beyond monetary support, involving time, energy, and focus to work closely with founders for success. Notable companies they have backed include ManyPets, Cazoo, Depop, Elvie, and WaveOptics. Their operations span London and New York, with a network of partners in the U.S. and Asia.

Octopus Ventures

Inflow

Inflow develops a science-based digital program intended to manage ADHD. Its mission is to equip ADHD people with the skills and support they need to reach their full potential.

Inflow is a UK-based mental care platform focused on treating individuals diagnosed with attention deficit hyperactivity disorder (ADHD) using cognitive behavioral therapy (CBT). Launched in 2020, its mobile app helps individuals develop healthy habits, practice ADHD-specific mindfulness techniques, reframes negative thoughts, and learn skills as well as their neurological differences.

New technologies are opening up mental health services to previously overbooked and underserved populations.

Mental Health Tech

Inflow is a UK-based mental care platform focused on treating individuals diagnosed with attention deficit hyperactivity disorder (ADHD) using cognitive behavioral therapy (CBT). Launched in 2020, its mobile app helps individuals develop healthy habits, practice ADHD-specific mindfulness techniques, reframes negative thoughts, and learn skills as well as their neurological differences.In <a href="https://sp-edge.com/updates/14872">November 2022</a>, the company acquired virtual mental health clinic Lina for an undisclosed sum. The acquisition was carried out by Inflow in order to expand its care offerings to provide more holistic care for individuals diagnosed with ADHD.

Boulder Care is a telehealth provider that offers virtual addiction treatment for substance use disorders, primarily focusing on opioid and alcohol use disorders. The company provides medical care, medication management, peer recovery coaching, and case management services through a mobile app, allowing patients to connect with a multidisciplinary care team, including physicians, nurse practitioners, peer recovery specialists, and social services support. Boulder Care's treatment approach includes medication-assisted treatment (MAT), prescribing medications such as buprenorphine-naloxone (Suboxone) for opioid use disorder and naltrexone, acamprosate, and others for alcohol use disorder. The company also delivers naloxone doses to patients to help reverse opioid overdoses.The company has implemented value-based payment arrangements with insurers, tying its financial success to patient outcomes. As of May 2024, Boulder Care had served over 12,000 patients across multiple states, with a concentration in Washington, Oregon, and Ohio. The company reports retention rates of 70%–80% of patients remaining in treatment after six months, significantly above the national average. Boulder Care had also expanded its services to include treatment for adolescents as of January 2024.Key customers and partnershipsBoulder Care has established partnerships with numerous health plans and employers to provide access to its services, including Elevance Health, UnitedHealth Community Plan, and Centene.

Boulder Care

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 7 Cups provides an emotional-support platform with a network of volunteer listeners. Users can anonymously access either one-on-one chats or group chats 24/7, free of charge for issues such as depression, anxiety, relationships and those related to the LGBTQ+ community. It also teaches users skills such as meditation to improve their lives. If users want additional support, the company also provides access to an online therapy platform with a network of 180 licensed therapists for a subscription plan of USD 150 per month. 7 Cups is available for users above 13 years of age (users between 13 and 17 years old engage with listeners who are specifically trained in teenage interactions).
 
 
 Volunteer peer listeners get free training and support as well as flexible scheduling. Once a user requests a chat, it will be directed to available listeners and if the user requests a specific listener, he will be connected as soon as the listener accepts the demand. The service is anonymous and the listener has no access to the details of the user unless the information is disclosed to the listener by the user in their conversations. As of January 2022, 7 Cups has facilitated more than 51 million conversations, served 25 million individuals, and had 300,000 trained listeners. The listeners serve in 180 countries in 140 languages.
 
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7 Cups

wayForward provides technology-supported behavioral health and emotional wellness services for employers planning to make services available to their employees. It uses a screening procedure designed by neuropsychologists to triage and help employee members get clinically relevant mental healthcare. The company provides a self-guided app, text-based coaching, video visits, telepsychiatry, and if required, in-person visits or an on-site counselor. wayForward leverages its evidence-based approach and artificial intelligence in delivering its services and claims that it has been able to reduce anxiety symptoms by 48% and depression symptoms by 59%.The company raised USD 2 million in a seed round in June 2020, which brought total funding to USD 4.5 million. DarioHealth, a chronic disease management platform based in Israel, signed a definitive agreement to acquire 100% of wayForward in May 2021 for a total consideration of USD 30 million. As of May 2021, the wayForward had approximately 20,000 members and was available in North America, Australia, and Europe.

wayForward

Coa is a mental health company that conducts online classes led by licensed therapists for mental health users. The classes focus on conditions such as stress, anxiety, confidence and relationships. The company raised USD 3 million in a seed round in October 2020 from investors led by Crosslink Capital.

Meru Health is an online platform that connects patients experiencing stress, depression, anxiety, burnout, and other mental health issues to licensed therapists. The company was founded by Kristian Ranta in 2016 after his older brother died from suicide after battling depression. The platform offers a 12-week program and personalized text-based coaching services and virtual workshops. Meru also provides access to progress reports and anonymous peer support groups as well as sleep, nutrition, and mindfulness advice. The program utilizes a wearable device that monitors heart rate variability and provides real-time feedback, allowing patients to visualize the connection between their mental and physical health.In March 2024, Meru Health introduced a 100% fees-at-risk pricing model for healthcare payers and employers, guaranteeing outcomes, access, and engagement. This value-based care approach aims to incentivize enrollment, quality care delivery, cost management, and medical cost savings.The company reported a 10x YoY growth in its customer base in 2020 and plans to serve 10 million users by 2027. The company also achieved 8x YoY growth in revenue in 2020 amid an increase in demand in mental health services brought about by the Covid-19 pandemic.Key customers and partnershipsMeru Health partners with major health insurance providers, including Humana, Aetna, and Moda Health. In January 2022, the company joined Evernorth's national behavioral health provider network, making its services available to Cigna health plan customers accessing benefits through their employer or individual and family plans.Meru Health also works with employer groups to provide mental healthcare for employees. In September 2022, Meru Health and clinical trial platform Curebase <a href="https://sp-edge.com/updates/13230">announced a partnership </a>to carry out a three-year clinical trial to measure the effectiveness of Meru Health’s 12-week digital depression treatment targeting primary care patients. The study was funded by the National Institutes of Health’s Small Business Innovation Research program.

Meru Health

Online peer-to-peer platform and support system that connects mental health communities.

Mobile-based apps and FDA-approved software that incorporate evidenced-based cognitive behavioral therapy to prevent, treat, or manage mental and behavioral conditions in conjunction with or as a replacement for traditional medication.

Products for behavioral health and mental health tracking, measurement-based care, and real-time remote monitoring of patients.

Subscription or membership-based platforms and apps to connect therapists, psychiatrists or behavioral health coaches with patients.

Offers virtual offerings for mental health consultations

Mental healthcare services offer personalized care tailored to a user's needs and treatment progression

There are mental health providers offering services specifically to help LGBTQ+ or BIPOC individuals

Several mental health technology providers offer therapy services rendered by AI/ML technology

Inflow

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