UPMC Enterprises offers smart integration of technology needed to solve the complex problems facing the health care industry. At UPMC Enterprises, they help create health care innovations that will impact the lives of patients in meaningful, lasting ways. To deliver on this promise, they’ve chosen a few focus areas where their insights about health care’s future give us a unique advantage. They’ve built an impressive team with expertise in health care investing that’s second to none. When they choose to work with an entrepreneur, they work side by side with them and provide full access to UPMC’s vast resources. As an organization dedicated to Life Changing Medicine, UPMC has defined a bold mission: to shape the future of health care through innovation. At UPMC Enterprises, they help bring this mission to life by turning innovative ideas into growing, thriving businesses. That’s why they want the best to choose UPMC Enterprises. They wouldn’t have it any other way.

UPMC Enterprises

Smile CDR

Smile CDR specializes in delivering fast, secure, compliant data infrastructures to enable for data intensive sectors such as healthcare.

Smile Digital Health is a health information technology company focused on delivering better global health through open standards. The company offers an enterprise-grade, open framework data fabric and integration platform called Smile CDR (Clinical Data Repository), powered by the HL7 FHIR standard-based clinical data repository. Smile CDR enables healthcare organizations to ingest, transform, store, enrich, analyze, aggregate, and meaningfully share health information to power digital transformation.

Care without Boundaries enabled by Smile Digital Health on AWS

Smile Digital Health Expands Work on AWS

Smile CDR Receives U.S. Health Interoperability Standards Certification for Patient Clinical Data

Smile Digital Health Closes $30 Million in Series B Funding to Progress Innovation as World-Leading Health Data Fabric

Smile CDR closes Series B growth capital

Enabling the health systems to seamlessly connect, exchange, and interpret shared data

Hospital Interoperability

Smile CDR Rebrands to Smile Digital Health

Smile Digital Health is a health information technology company focused on delivering better global health through open standards. The company offers an enterprise-grade, open framework data fabric and integration platform called Smile CDR (Clinical Data Repository), powered by the HL7 FHIR standard-based clinical data repository. Smile CDR enables healthcare organizations to ingest, transform, store, enrich, analyze, aggregate, and meaningfully share health information to power digital transformation.
Smile CDR is a composable FHIR framework that allows organizations to address interoperability challenges and meet their specific requirements. It supports ingesting data in various industry formats and transforming it into FHIR standard resources. The platform offers capabilities such as identity management, compliance with the 21st Century Cures Act, and integration with existing healthcare systems through its AppSphere marketplace.
Smile CDR harnesses open standards to enable data consolidation and integration with other systems and datasets, facilitating applications like CMS FHIR compliance solutions, Health Information Exchanges (HIEs), and value-based care outcomes tracking.
Key customers and partnerships
In October 2022, Smile Digital Health achieved Amazon HealthLake (AHL) Connector partner status in the AWS Partner Network, demonstrating its ability to transform healthcare data into FHIR format for use across AHL applications and services. The company also passed the AWS Foundational Technical Review for deploying its solutions on AWS services like Amazon EKS and Amazon RDS.
In August 2022, Smile CDR received its third certification from Drummond Group's Payer and Patient Access FHIR Certification Program, showing compliance with the CMS Interoperability and Patient Access Final Rule for providing patients' clinical data via the Patient Access API. The company had previously achieved certifications for Drug Formulary API and Provider Directory API support.

Redox is a leading healthcare technology company that provides a secure and efficient platform for exchanging healthcare data. Its core offering is an integration engine that enables seamless connectivity between various healthcare systems, electronic health records (EHRs), and digital health applications. By acting as a single, standardized API endpoint, Redox simplifies the complex process of interoperability, allowing healthcare organizations to share and access patient data seamlessly.
Redox's platform is built on a standardized data model format, utilizing HTTPS communication with JSON to facilitate secure and convenient integration for healthcare applications. The company's ecosystem encompasses a vast network of over 2,000 healthcare delivery organizations, 350 healthcare software vendors, and connections to more than 90 EHR systems. This extensive reach enables Redox's customers, including payers, providers, and digital health companies, to exchange data with a wide range of healthcare stakeholders.
The company's offerings include Redox Nexus, a managed integration platform that facilitates interoperability between legacy formats and the current FHIR standard; Redox Nova, which enables cloud-based data integration and translation of legacy standards into FHIR; Redox Access, which connects to national clinical networks like Carequality and DirectTrust for seamless clinical data exchange; and Redox Chroma, an Enterprise Master Patient Index (EMPI) solution that aggregates patient records across multiple data sources.
Key customers and partnerships
Redox has established partnerships with leading healthcare organizations and companies, including Mytonomy, a video-based patient engagement company. Mytonomy leverages Redox's integration capabilities to synchronize the assignment and viewership of its educational video modules with health system EHRs, ensuring seamless documentation of patient education activities.
Furthermore, Redox has collaborated with Columbia University Medical Center's Department of Cardiology, enabling the integration of Mytonomy's patient education platform with the center's EHR system.
The company has also forged alliances with healthcare consulting firms like Productive Edge, providing joint solutions for healthcare data integration and strategy development.

Redox

Moxe Health, based in Madison, WI, is a healthcare interoperability company that utilizes innovative technology to simplify and improve the secure exchange of clinical data and crucial insights between healthcare payers and providers. Through its API-enabled solutions compatible with leading electronic health records (EHRs), Moxe fosters meaningful collaboration within the healthcare ecosystem by connecting various stakeholders and facilitating faster, more cost-effective data exchange.
The company's digital release of information (ROI) product automates requests for medical charts, enabling providers to securely fulfill such requests in seconds, eliminating manual processes, paper, faxes, and phone calls. Additionally, Moxe's convergence product allows payers to input their insights directly into the EHR for providers to access. By streamlining data sharing, Moxe empowers providers and payers to optimize operations, improve accuracy, and deliver better financial and clinical outcomes.
As of June 2022, Moxe's network connected major health systems, national health plans representing over 75 million lives, leading third-party requestors, and more than 60 hospital systems. The company aimed to accelerate its mission of advancing interoperability and making healthcare more affordable by eliminating administrative waste through its patient-centric solutions.
Key customers and partnerships
Moxe Health partners with leading healthcare organizations, including Allscripts, whose Allscripts Sunrise EHR users can leverage Moxe's Digital ROI solution for efficient data exchange between health systems, payers, and third-party requestors.

Moxe Health

Particle Health is a developer-friendly API platform that aggregates and standardizes data from over 270 million patients' medical records across thousands of healthcare sources in the US. The company's comprehensive API enables healthcare providers and digital health companies to easily obtain clinical data points and actionable patient health insights through a single integration. Particle Health's technology performs patient matching behind the scenes to connect accounts within HIPAA authorization, overcoming the challenges of accessing medical records across different portals and providers.
Since its inception, Particle Health has achieved significant milestones, including a 90% success rate in finding patient records and an average of 105 records per patient search as of July 2022. The company has expanded its offering beyond electronic medical records (EMRs) to include data sources such as pharmacy records, admission, discharge, and transfer (ADT) notifications, and billing claims data, with plans to integrate genomics and other sources in the future.
Key customers and partnerships
Particle Health has formed notable partnerships and collaborations with various healthcare companies and organizations. For instance, xCures, a technology platform that uses artificial intelligence and predictive modeling to identify and rank treatment options for cancer patients, has integrated Particle Health's Specialty Search capabilities. This integration allows xCures to efficiently access comprehensive oncology data, leading to a significant increase in program enrollment and better patient care management.
Another strategic partnership was announced in November 2023 between Particle Health and Hona, a customizable AI product that converts health records into concise patient overviews. By integrating Particle Health's API for medical record retrieval, Hona can analyze and present a complete view of a patient's health history, enabling providers to make informed clinical decisions and streamline care encounters.

Particle Health

Verto Health is a Canadian digital health company that offers a Digital Twin Orchestration Platform. Its patented machine learning technology consolidates data from various sources to create normalized, contextual snapshots – known as 'Digital Twins' – of each patient's healthcare journey. Verto's platform then automates actions across different systems while securely managing consent, data, and communication.
In October 2022, Unity Health Toronto implemented Verto's technology to help manage ambulatory patient flow, streamline consent management, and transform patient experience across dozens of ambulatory clinics. Verto's solution allowed Unity Health to coordinate and engage with patients before, during, after, and in-between hospital visits, supporting care pathway management and enhancing the patient experience.
Key customers and partnerships
In July 2023, Verto Health partnered with the Centre for Addiction and Mental Health (CAMH) to develop a web-based Digital Front Door platform. This platform aimed to digitize the patient journey and support data-driven, measurement-based care for CAMH's patients and care providers. The collaboration involved co-designing, configuring, and implementing the Digital Front Door to act as a single-point of entry for CAMH patients and families, enabling virtual care and integrating various patient-facing information systems.

Verto Health

Wellsheet is the leading provider of a Smart Electronic Health Record (EHR) User Interface (UI) solution that aims to reduce clinician burnout and increase efficiency and usability of EHRs. The company's technology utilizes artificial intelligence (AI) and machine learning algorithms to synthesize, summarize, and elevate relevant clinical data from EHRs like Cerner, Epic, or athenahealth, as well as other data sources.Wellsheet's Smart EHR UI predicts and prioritizes the most pertinent data based on a clinician's specialty and workflow habits, assembling it in an intuitive and customizable manner. This enables providers to quickly arrive at accurate clinical insights without compromising patient interactions. By embedding within existing EHRs, the solution helps clinicians understand what needs to be done and make more informed decisions while reducing errors.As of July 2022, Wellsheet had an enterprise-wide deployment with over 10,000 clinicians using its interface, reducing the time spent in EHRs for physicians, nurses, and care managers. The company's FHIR-based APIs allow for rapid implementation across multiple data sources within weeks and minimal training requirements.

Wellsheet

Includes tools that allow healthcare providers to aggregate clinical data (both structured and unstructured) from a variety of sources and share this information with other providers, patients, or insurance providers.

Platforms that provide interoperability APIs and developer toolkits that allow siloed healthcare applications or systems to communicate with each other. Targeted at both healthcare providers and digital health apps.

Software platforms that integrate patient information (including social determinants of health) from multiple sources to digital tools. These tools support patient management and offer actionable insights on a patient's health by leveraging data analytics.

Healthcare data is exchanged, shared, and interpreted via digital mediums

AI/ML algorithms aggregate and standardize data for seamless sharing between healthcare systems

IoT technology is being used to improve hospital interoperability, connectivity, and secure data sharing

Smile CDR

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