Founded by serial entrepreneur Kevin Ryan, AlleyCorp is both a startup studio and fund that founds companies and invests in early stage companies. AlleyCorp is exclusively focused on investing in transformational companies in New York City. Since its inception, we have launched companies that have raised over $1B+ in funding with an aggregate value of $10B+. As a venture / idea studio, AlleyCorp originates the idea, forms the founding team, funds the initial 6-12 months, launches the company, and maintains integral leadership throughout the company's lifecycle. Some companies that have been founded through AlleyCorp include MongoDB, Business Insider, Gilt Groupe, Zola, Nomad Health, Workframe, and CoEdition.  AlleyCorp will also invest in very early stage companies usually as the first seed investor.  Moreover, we believes in supporting first time founders. Our goal is to co-create and invest in truly transformational companies with inspiring leaders.

AlleyCorp

Andreessen Horowitz is a venture capital firm specializing in investing in seed, start-ups, early, mid-stage, growth, and late-stage. It prefers to invest in the social media business and technology sector with a focus on software, back-end infrastructure, the infrastructure of the Internet, cloud computing, enterprise software and services, consumer, business Internet, mobile-Internet, consumer Internet, cloud computing, data storage, social network browsers data-storage, consumer electronics, networking functions, software related biology, biotech, and medicine companies at the intersection of computer science and life sciences with a focus on digital therapeutics, cloud technology in biology, and computational medicine.

Andreessen Horowitz

Viking Global Investors is an investment firm that uses fundamental analysis to select investments across industries and geographies. It is a global investment firm managing more than twenty billion in capital across long-short equity and long-only strategies. The firm was established in 1999 and is headquartered in Greenwich, Connecticut, with offices in New York City, Hong Kong, and London.

Viking Global Investors

SV Angel is a service organization, investing in founders who share these values. They support entrepreneurs in building lasting companies by assisting at key inflection points and leveraging networks to help them propel their businesses forward.

SV Angel

Pearl Health

Pearl Health is powering the future of healthcare. We help primary care providers and organizations deliver quality healthcare to the patients who need it most, when they need it most — and get rewarded for keeping patients healthy. Our technology, services, and financial tools enable better, more proactive care, decrease total cost of care across patient panels, and optimize performance in value-based care models for Traditional Medicare and Medicare Advantage. We are a team of physicians and public health experts, technologists, healthcare innovators, and experienced risk management professionals who believe that primary care providers are the key to addressing our healthcare system’s biggest challenges. Since its founding in 2020, Pearl has expanded to partner with thousands of primary care providers in practices and organizations across 44 states. Our investors include Andreessen Horowitz, Viking Global Investors, AlleyCorp, and SV Angel.

Pearl Health offers a data science-backed platform to assist primary care providers (PCPs) in treating patients better. The platform analyzes patient information and generates insights and recommendations, along with data visualizations, patient information tracking, and comprehensible patient reports. This enables clinicians to understand, prioritize, and treat patients who require extra care.

Membership-based, non-insurance healthcare companies helping maintain a steady state of well being.

Preventive Healthcare

Synapticure, Pearl Health partner to give personalized care to Medicare patients

Pearl Health offers a data science-backed platform to assist primary care providers (PCPs) in treating patients better. The platform analyzes patient information and generates insights and recommendations, along with data visualizations, patient information tracking, and comprehensible patient reports. This enables clinicians to understand, prioritize, and treat patients who require extra care.The company offers the Accountable Care Organization Realizing Equity, Access, and Community Health (ACO REACH) model as an alternative payment model to PCPs, providing them an avenue of stable monthly payments and shared savings.&nbsp;As of January 2024, Pearl partnered with over 1,600 PCP across 43 states and Washington DC.&nbsp;Key customers and partnershipsThe company has several key partnerships to expand its value-based care models, including <a href="https://sp-edge.com/updates/19438">Story Health</a> (June 2023), Walgreens (September 2023), Yuvo Health (October 2023), and ViCare Health (in October 2023).&nbsp;Funding and financialsIn January 2023, Pearl Health raised USD 75 million in a <a href="https://sp-edge.com/updates/15984">Series B</a> funding round led by Andreessen Horowitz's Growth Fund and Viking Global Investors. The funds raised were used to fuel the company’s growth initiatives, including expanding its network and pursuing new partnerships and toward R&amp;D.&nbsp;In January 2024, the company reported that its revenue had grown 20x since 2022.

Pearl Health offers a data science-backed platform to assist primary care providers (PCPs) in treating patients better. The platform analyzes patient information and generates insights and recommendations, along with data visualizations, patient information tracking, and comprehensible patient reports. This enables clinicians to understand, prioritize, and treat patients who require extra care.The company offers the Accountable Care Organization Realizing Equity, Access, and Community Health (ACO REACH) model as an alternative payment model to PCPs, providing them an avenue of stable monthly payments and shared savings.&nbsp;As of January 2024, Pearl partnered with over 1,600 PCP across 43 states and Washington DC. Further, n January 2024, the company reported that its revenue had grown 20x since 2022.Key customers and partnershipsThe company has several key partnerships to expand its value-based care models, including <a href="https://sp-edge.com/updates/19438">Story Health</a> (June 2023), Walgreens (September 2023), Yuvo Health (October 2023), and ViCare Health (in October 2023). In <a href="https://sp-edge.com/updates/32705">August 2024</a>, the company partnered with PraxisCare and Adaugeo to expand value-based care services across multiple Medicare Accountable Care Organizations. The company also partnered with Synapticure, a telemedicine company for neurodegenerative diseases, in <a href="https://sp-edge.com/updates/32914">August 2024</a> to support dementia patients through the CMS GUIDE program.

Cardiomo Care is developing noninvasive wearable devices to alert users and caretakers when there are abnormalities in the heartbeat. The company’s AI engine, trained on existing and growing data sets, can predict potential heart issues up to two hours before they occur, enabling early detection and intervention for arrhythmias and other cardiovascular diseases (CVDs).The company's product, CardiomoPatch, is a waterproof, wearable patch capable of long-term wear with a 10-day battery life. The patch monitors a patient's cardiac data, including ECG outputs, breathing, and skin temperature, and transmits the data via a mobile app for analysis by Cardiomo's AI engine.&nbsp;As of May 2024, the company is yet to commercialize its product and has over 1,600 pre-orders.

Cardiomo Care

Omada is a prevention-focused digital therapeutics startup that helps members achieve health goals through lifestyle changes. It offers four evidence-based, virtual prevention programs for managing hypertension, musculoskeletal (MSK) issues, prediabetes, and diabetes.Omada offers real-time data tracking through connected devices (such as wireless scales, blood pressure, and glucose monitors) and access to personalized coaching sessions via a mobile app as part of its prevention program. It also provides an online community of peers with similar health conditions to discuss challenges and provide support. In May 2021, Omada became the first fully-virtual healthcare provider to earn the National Committee for Quality Assurance’s Population Health Program Accreditation for its type 2 diabetes and type 2 diabetes + hypertension programs.Unlike its peers, Omada operates a performance-based business model where it charges clients an enrollment fee based on the number of users and a performance fee based on how much weight their employees lose. In May 2020, the company acquired virtual physical therapy startup Physera.Key customers and partnershipsAs of May 2024, Omada had more than 1 million members from more than 1,900 enterprise clients across all 50 US states. Its B2B employer and health plan client base include key clients such as American Eagle, Kaiser Permanente, Costco Wholesale, 3M, and Marvin. Additionally, the company has partnered with health systems and hospitals such as Intermountain Healthcare to provide its preventive programs as a covered benefit.In <a href="https://sp-edge.com/updates/15587">January 2023</a>, the company partnered with health service company Castell (a subsidiary of Intermountain Healthcare) to provide its diabetes programs to members from Intermountain Healthcare’s primary care providers in its Utah Medical Group. Further in <a href="https://sp-edge.com/updates/25245">January 2024</a>, the company partnered with Amazon to expand access to its cardiometabolic program.

Omada Health

VillageMD provides primary care services for patients. It also provides tools, technology, and staffing support needed for physicians to deliver high-quality services. VillageMD’s service delivery methods include traditional freestanding clinics, Village Medical at Walgreens co-located clinics, as well as at-home and around-the-clock virtual visits. It also leverages a team-based approach to care where physicians lead nurse practitioners, pharmacists, mental health specialists, and dietitians to offer a holistic care program. The technology of VillageMD includes docOS, an operating system that enables better patient care by connecting various clinical source systems with ongoing patient-generated data coupled with an AI engine to continuously analyze messages to enable patient self-care.The company made several acquisitions to expand its footprint: 1) <a href="https://sp-edge.com/updates/14347">Summit Health</a> for USD 8.9 billion in November 2022, 2) Healthy Interactions, an interactive patient education platform, in February 2022, and 3) <a href="https://sp-edge.com/updates/16968">Starling Physicians</a>, a primary care and specialty care provider, in March 2023.Key customers and partnershipsIn June 2020, VillageMD and Walgreens Boots Alliance announced a collaborative effort to open at least 600 Village Medical centers at Walgreens across more than 30 US markets by 2025. Walgreens invested USD 5.2 billion in VillageMD (from the previously announced USD 1.0 billion), raising its ownership stake to 63% (from 30%).However, as of May 2024, Walgreens had plans to close 160 VillageMD clinics as part of a cost-cutting plan.

VillageMD

Cityblock Health is a value-based healthcare provider focused on delivering comprehensive care to underserved communities, primarily Medicaid and lower-income Medicare beneficiaries. The company combines primary care, behavioral health, and social services to address the complex physical, mental, and social needs of its members.Cityblock's model involves partnering with local community-based organizations and deploying multidisciplinary care teams that include doctors, nurses, behavioral health specialists, and community health workers. These teams provide personalized care through 24/7 access to multi-modal care delivery, including in-home visits, telehealth, and community health hubs.The services of Cityblock are available to members at no additional cost if they are covered by an eligible health plan.Key Customers and PartnershipsAs of May 2024, the company’s services were available in seven states across the US and served over 100,000 members.In May 2024, it partnered with <a href="https://sp-edge.com/updates/29647">Sunshine Health</a> to expand to Florida, and, in <a href="https://sp-edge.com/updates/13270">September 2022</a>, it partnered with MDwise to expand into Indiana. Prior to that, the company had partnered with insurance providers such as ConnectiCare (Connecticut), Tufts Health Plan (Massachusetts), Emblem Health (New York), Healthy Blue (North Carolina), Molina Healthcare (Ohio) and CareFirst (Washington DC).Funding and FinancialsCityblock is a spin-off of Sidewalk Labs, an Alphabet company that incubates and invests in tech companies and products to improve urban infrastructure. It completed a USD 400 million Series D funding round led by Softbank in <a href="https://sp-edge.com/updates/5326">September 2021</a>, valuing the company at USD 5.7 billion. The funds were used to expand its services.

Cityblock Health

Everside Health (formerly Paladina Health) offers preventative care for chronic conditions and primary, mental and occupational healthcare treatments for acute conditions. Patients benefit from around-the-clock access to care, same-day or next-day appointments for in-person, and virtual care visits with zero copays.Everside aims to generate around 17% healthcare cost savings in three years and 31% in five years for its corporate members by leveraging a data-driven approach to care coordination.The company leverages data from past medical records, predictive analytics, and AI in the delivery of preventative care services.Founded in 2010 under the name Paladina Health, the company was rebranded in November 2020 as Everside Health following a merger between three primary care groups (Paladina, Activate Healthcare, and Healthstat). Furthermore, in February 2024, Everside Health merged with primary care provider Marathon Health to form a combined entity that would operate as Marathon Health, and, as of May 2024, the integration was ongoing.Key customers and partnershipPost-merger with Marathon Health, the combined entity would serve 2.5 million patients through over 680 clinics across 41 states.Funding and financialsThe company received its most recent investment in July 2022, amounting to USD 164 million in growth equity funding. The round was led by New Enterprise Associates (NEA). The funds were allocated toward growing its market presence and exploring opportunities for M&amp;A as well as to enhance and improve its product features. Additionally, the firm planned to expand its coverage of specialty care services aimed at individuals, employers, and union organizations.

Everside Health

Platforms offer a subscription-based or B2B-sponsored, evidence-based program for managing a specific long-term health condition.

DPCs offer value-based primary and preventive care services addressing whole-person (social, mental, physical) needs for a fixed monthly or annual fee paid by either the patient, insurance provider, or employer.

Companies offer B2B and D2C evidence-based treatments delivered via software programs to prevent and manage a variety of chronic conditions.

Tools that collect and analyze real-time patient data that supports healthcare providers with clinical decisions,  improves patient outcomes, and reduces medical errors.

Companies offer independent physician practices and hospitals with the tools (patient engagement, care coordination, administrative services) to help manage and improve clinical health outcomes of a defined group of individuals or large populations.

Platforms are used to track and gather patient health-related information via either a connected device or at-home test kits to detect the early onset of disease and identify any abnormalities in readings—but do not include a treatment plan.

To gather large amounts of real-time data for chronic care management, DTx, and patient monitoring

XR used by some startups for chronic pain management

Offers digital means of providing direct primary care, passive remote monitoring, chronic care management, etc.

AI/ML is used in predictive analytics, diagnostics tools, and population management

Offers tailored preventive interventions and treatments to the specific needs and characteristics of each individual

ANALYST_QUICK_TAKE

PROMINENT_CATEGORY

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 Synapticure, a telemedicine company specializing in neurodegenerative diseases, has partnered with Pearl Health, a company focused on value-based care technologies. The partnership aims to support dementia patients through the CMS GUIDE (Guiding an Improved Dementia Experience) program.
 The primary objective of this collaboration is to enhance the quality of life for dementia patients as well as caregivers by enabling them to access specialized neurologists, behavioral health support, and exhaustive caregiver assistance. Pearl Health primary care providers are in a position to refer Medicare patients to Synapticure for anticipatory, value-based dementia care.
 As part of the CMS GUIDE program, dementia patients are provided with fully covered online consultations with Synapticure neurologists and around 80 hours of respite care services at no extra charges. This landmark collaboration seeks to alleviate the burden of caregivers and support patients to continue living safely in their homes and communities.

</div> Analyst QuickTake: 
 In April 2024, Synapicture <a href="https: 
//sp-edge.com/updates/28626"> partnered </a> with the Amyotrophic Lateral Sclerosis (ALS) Association to improve access and quality of care for ALS patients across the US. Through the partnership, Synapticure's telemedicine platform was made available to members of the ALS Association to supplement in-person visits at certified ALS treatment centers. Both of Synapicture’s partnership agreements that it secured in 2024 serve to increase the company’s market reach and help further its goal of making neurodegenerative care more accessible, compassionate, and personalized.

Pearl Health

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