Hoxton Ventures focuses on startups that either disrupt existing industries or invent entirely new market categories. Hoxton typically invests between $500,000 and $5 million into pre-seed, seed, and Series A stage companies, and follows its capital through the life of the company.  The firm is based in London and invests all across Europe.

Hoxton Ventures

Seedcamp is Europe's seed fund, identifying and investing early in world-class founders attacking large, global markets and solving real problems using technology. The Seedcamp Nation includes over 400 startups building breakout businesses that change the way people live, interact and buy and includes publicly listed UiPath, Wise, and unicorns Revolut, Hopin, Sorare, Pleo, and wefox along with fast-growing businesses such as Grover, viz.ai and Ezra.  Seedcamp fast-tracks a founder's vision and creates value through immediate access to smart capital, a lifelong community of support and a global network built upon more than a decade's experience backing exceptional talent. Seedcamp fast-tracks a founder's vision and creates value through immediate access to smart capital, a lifelong community of support, and a global network built upon more than a decade's experience backing exceptional talent.

Seedcamp

Limbo

Limbo provides wearable technology that was created for diabetes management. These continuous glucose monitors (CGMs) transmit near real-time glucose data, providing instant feedback (via a companion mobile app) on how the body metabolizes different foods or responds to lifestyle decisions around exercise and sleep.

<div>Limbo is a data-driven weight loss program that monitors blood glucose levels. Limbo is considered similar to having a satnav that directs people to lose weight. It uses the body's data to guide individuals on the quickest, most personalized path to long-term weight loss. The platform provides real-time guidance, a heart rate monitor, including the Limbo Band, or any wearable tracker that connects to Apple Health such as the Apple Watch or Oura Ring.&nbsp;</div>

Membership-based, non-insurance healthcare companies helping maintain a steady state of well being.

Preventive Healthcare

Limbo is a digital weight loss and body transformation service that guides users to healthier habits by leveraging real-time biodata from wearables, including a continuous glucose monitor (CGM), an app, and a combination of human coaches and artificial intelligence (AI). The service is based on over 30 years of research by co-founder and physiologist Tony Martin, focused on understanding how blood glucose levels regulate the body's energy system.

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Weight loss platform Limbo raises $6m in seed round

Limbo is tackling obesity with a pair of wearables and decades of physiology

Read Customer Service Reviews of limborevolution.com

Functional Nutrition

<div>
 
 Limbo is a data-driven weight loss program that monitors blood glucose levels. Limbo is considered similar to having a satnav that directs people to lose weight. It uses the body's data to guide individuals on the quickest, most personalized path to long-term weight loss. The platform provides real-time guidance, a heart rate monitor, including the Limbo Band, or any wearable tracker that connects to Apple Health such as the Apple Watch or Oura Ring.&nbsp;
 
 
 Funding and Financials
 
 
 In September 2022, Limbo raised USD 6 million in a seed funding round led by Hoxton Ventures. The funding was expected to be used to launch its subscription services in the UK and Ireland.
 
</div>

Cardiomo Care is developing noninvasive wearable devices to alert users and caretakers when there are abnormalities in the heartbeat. The company’s AI engine, trained on existing and growing data sets, can predict potential heart issues up to two hours before they occur, enabling early detection and intervention for arrhythmias and other cardiovascular diseases (CVDs).The company's product, CardiomoPatch, is a waterproof, wearable patch capable of long-term wear with a 10-day battery life. The patch monitors a patient's cardiac data, including ECG outputs, breathing, and skin temperature, and transmits the data via a mobile app for analysis by Cardiomo's AI engine.&nbsp;As of May 2024, the company is yet to commercialize its product and has over 1,600 pre-orders.

Cardiomo Care

Omada is a prevention-focused digital therapeutics startup that helps members achieve health goals through lifestyle changes. It offers four evidence-based, virtual prevention programs for managing hypertension, musculoskeletal (MSK) issues, prediabetes, and diabetes.Omada offers real-time data tracking through connected devices (such as wireless scales, blood pressure, and glucose monitors) and access to personalized coaching sessions via a mobile app as part of its prevention program. It also provides an online community of peers with similar health conditions to discuss challenges and provide support. In May 2021, Omada became the first fully-virtual healthcare provider to earn the National Committee for Quality Assurance’s Population Health Program Accreditation for its type 2 diabetes and type 2 diabetes + hypertension programs.Unlike its peers, Omada operates a performance-based business model where it charges clients an enrollment fee based on the number of users and a performance fee based on how much weight their employees lose. In May 2020, the company acquired virtual physical therapy startup Physera.Key customers and partnershipsAs of May 2024, Omada had more than 1 million members from more than 1,900 enterprise clients across all 50 US states. Its B2B employer and health plan client base include key clients such as American Eagle, Kaiser Permanente, Costco Wholesale, 3M, and Marvin. Additionally, the company has partnered with health systems and hospitals such as Intermountain Healthcare to provide its preventive programs as a covered benefit.In <a href="https://sp-edge.com/updates/15587">January 2023</a>, the company partnered with health service company Castell (a subsidiary of Intermountain Healthcare) to provide its diabetes programs to members from Intermountain Healthcare’s primary care providers in its Utah Medical Group. Further in <a href="https://sp-edge.com/updates/25245">January 2024</a>, the company partnered with Amazon to expand access to its cardiometabolic program.

Omada Health

VillageMD provides primary care services for patients. It also provides tools, technology, and staffing support needed for physicians to deliver high-quality services. VillageMD’s service delivery methods include traditional freestanding clinics, Village Medical at Walgreens co-located clinics, as well as at-home and around-the-clock virtual visits. It also leverages a team-based approach to care where physicians lead nurse practitioners, pharmacists, mental health specialists, and dietitians to offer a holistic care program. The technology of VillageMD includes docOS, an operating system that enables better patient care by connecting various clinical source systems with ongoing patient-generated data coupled with an AI engine to continuously analyze messages to enable patient self-care.The company made several acquisitions to expand its footprint: 1) <a href="https://sp-edge.com/updates/14347">Summit Health</a> for USD 8.9 billion in November 2022, 2) Healthy Interactions, an interactive patient education platform, in February 2022, and 3) <a href="https://sp-edge.com/updates/16968">Starling Physicians</a>, a primary care and specialty care provider, in March 2023.Key customers and partnershipsIn June 2020, VillageMD and Walgreens Boots Alliance announced a collaborative effort to open at least 600 Village Medical centers at Walgreens across more than 30 US markets by 2025. Walgreens invested USD 5.2 billion in VillageMD (from the previously announced USD 1.0 billion), raising its ownership stake to 63% (from 30%).However, as of May 2024, Walgreens had plans to close 160 VillageMD clinics as part of a cost-cutting plan.

VillageMD

Cityblock Health is a value-based healthcare provider focused on delivering comprehensive care to underserved communities, primarily Medicaid and lower-income Medicare beneficiaries. The company combines primary care, behavioral health, and social services to address the complex physical, mental, and social needs of its members.Cityblock's model involves partnering with local community-based organizations and deploying multidisciplinary care teams that include doctors, nurses, behavioral health specialists, and community health workers. These teams provide personalized care through 24/7 access to multi-modal care delivery, including in-home visits, telehealth, and community health hubs.The services of Cityblock are available to members at no additional cost if they are covered by an eligible health plan.Key Customers and PartnershipsAs of May 2024, the company’s services were available in seven states across the US and served over 100,000 members.In May 2024, it partnered with <a href="https://sp-edge.com/updates/29647">Sunshine Health</a> to expand to Florida, and, in <a href="https://sp-edge.com/updates/13270">September 2022</a>, it partnered with MDwise to expand into Indiana. Prior to that, the company had partnered with insurance providers such as ConnectiCare (Connecticut), Tufts Health Plan (Massachusetts), Emblem Health (New York), Healthy Blue (North Carolina), Molina Healthcare (Ohio) and CareFirst (Washington DC).Funding and FinancialsCityblock is a spin-off of Sidewalk Labs, an Alphabet company that incubates and invests in tech companies and products to improve urban infrastructure. It completed a USD 400 million Series D funding round led by Softbank in <a href="https://sp-edge.com/updates/5326">September 2021</a>, valuing the company at USD 5.7 billion. The funds were used to expand its services.

Cityblock Health

Everside Health (formerly Paladina Health) offers preventative care for chronic conditions and primary, mental and occupational healthcare treatments for acute conditions. Patients benefit from around-the-clock access to care, same-day or next-day appointments for in-person, and virtual care visits with zero copays.Everside aims to generate around 17% healthcare cost savings in three years and 31% in five years for its corporate members by leveraging a data-driven approach to care coordination.The company leverages data from past medical records, predictive analytics, and AI in the delivery of preventative care services.Founded in 2010 under the name Paladina Health, the company was rebranded in November 2020 as Everside Health following a merger between three primary care groups (Paladina, Activate Healthcare, and Healthstat). Furthermore, in February 2024, Everside Health merged with primary care provider Marathon Health to form a combined entity that would operate as Marathon Health, and, as of May 2024, the integration was ongoing.Key customers and partnershipPost-merger with Marathon Health, the combined entity would serve 2.5 million patients through over 680 clinics across 41 states.Funding and financialsThe company received its most recent investment in July 2022, amounting to USD 164 million in growth equity funding. The round was led by New Enterprise Associates (NEA). The funds were allocated toward growing its market presence and exploring opportunities for M&amp;A as well as to enhance and improve its product features. Additionally, the firm planned to expand its coverage of specialty care services aimed at individuals, employers, and union organizations.

Everside Health

Platforms offer a subscription-based or B2B-sponsored, evidence-based program for managing a specific long-term health condition.

DPCs offer value-based primary and preventive care services addressing whole-person (social, mental, physical) needs for a fixed monthly or annual fee paid by either the patient, insurance provider, or employer.

Companies offer B2B and D2C evidence-based treatments delivered via software programs to prevent and manage a variety of chronic conditions.

Tools that collect and analyze real-time patient data that supports healthcare providers with clinical decisions,  improves patient outcomes, and reduces medical errors.

Companies offer independent physician practices and hospitals with the tools (patient engagement, care coordination, administrative services) to help manage and improve clinical health outcomes of a defined group of individuals or large populations.

Platforms are used to track and gather patient health-related information via either a connected device or at-home test kits to detect the early onset of disease and identify any abnormalities in readings—but do not include a treatment plan.

To gather large amounts of real-time data for chronic care management, DTx, and patient monitoring

XR used by some startups for chronic pain management

Offers digital means of providing direct primary care, passive remote monitoring, chronic care management, etc.

AI/ML is used in predictive analytics, diagnostics tools, and population management

Offers tailored preventive interventions and treatments to the specific needs and characteristics of each individual

Limbo is a digital weight loss and body transformation service that guides users to healthier habits by leveraging real-time biodata from wearables, including a continuous glucose monitor (CGM), an app, and a combination of human coaches and artificial intelligence (AI). The service is based on over 30 years of research by co-founder and physiologist Tony Martin, focused on understanding how blood glucose levels regulate the body's energy system.
Limbo's approach revolves around monitoring users' blood glucose levels and providing personalized feedback and nudges to help them make better food choices and lifestyle adjustments. The goal is to flatten users' blood glucose levels, which Limbo refers to as the "Limbo line," by reducing the consumption of carbohydrates, sugars, and processed foods. This, in turn, is believed to promote weight loss and improve overall health.
The service involves wearing a CGM sensor, which continuously tracks users' glucose levels, and a smart wristband that monitors various biometrics, including heart rate, steps, and sleep patterns. Users also receive a smart scale to track their body weight, body fat, and muscle mass. This data is then analyzed by Limbo's AI system and human coaches, who provide tailored feedback and guidance through the Limbo app.
According to Limbo, early users have experienced an average body weight reduction of 12% within the first three months of using the service. The company claims that by helping users control their blood glucose levels and make better dietary choices, they can lose weight and improve their energy levels with relative ease.

Oviva is a health-tech company that provides app-guided therapy programs to help individuals adopt healthier eating and lifestyle habits. Their programs combine personalized care led by healthcare professionals, including dietitians, nutritionists, doctors, health coaches, psychologists, and exercise therapists, with their proprietary digital tools.
Oviva's approach involves empowering users with knowledge to track and understand their physiological data, set personal goals, and receive reminders and nudges through the Oviva app. Users can record their weight, HbA1c levels, food intake, and connect wearable devices, enabling their coaches to provide tailored coaching based on tracked habits.
By delivering care remotely and digitally, Oviva can scale its services while reducing costs. An Oviva coach can handle 4,000 to 5,000 user contacts per year, compared to around 900 appointments in traditional settings. Their services are available in the UK, Germany, Switzerland, and France, with country-specific websites catering to local healthcare systems.
In March 2023, Oviva launched a multi-site solution, displaying market-specific websites based on the visitor's location through GeoIP redirection. This approach ensures a seamless user experience tailored to each country's requirements.
Oviva partners exclusively with the National Health Service (NHS) in the UK to offer free digital weight management programs to participants. These 12-week programs provide one-on-one coaching, access to the Oviva app for self-monitoring, and an online learning portal.

Oviva

ZOE is a personalized nutrition program that aims to provide tailored dietary recommendations based on an individual's biological responses to different foods. The program utilizes at-home testing kits to analyze factors such as blood sugar control, blood fat control, and gut microbiome composition.
The testing process involves eating standardized muffins while wearing a continuous glucose monitor, collecting a stool sample for microbiome analysis, and performing a finger-prick blood test. Based on the results of these tests, ZOE generates personalized food scores and meal recommendations through its app.
The program claims to offer insights into optimal nutrition for each individual, helping to reduce dietary inflammation, improve gut health, and support overall metabolic health. ZOE's approach is founded on the principle that people have inherent differences in their responses to various food groups, and personalized dietary guidance can address these variations.
ZOE's technology and algorithms are based on research studies, such as the PREDICT studies conducted by King's College London and other institutions, which have examined the variability in postprandial responses among individuals. The program aims to move beyond traditional calorie counting and provide a more personalized approach to nutrition.

Lifesum is a digital nutrition platform that helps users build healthier eating habits through its innovative app. Founded in Stockholm, Sweden in 2013, the company provides a comprehensive suite of features to track meals, habits, and body measurements, enabling users to achieve their health and wellness goals. As of June 2024, Lifesum has over 65 million users worldwide across 250 countries, supporting 11 languages.
The app offers a user-friendly food diary allowing users to log meals by searching a database, scanning barcodes, or manually entering items. It tracks calorie intake, hydration levels, exercise routines, and provides personalized diet plans tailored to individual preferences and objectives, such as ketogenic, high protein, Scandinavian, or Mediterranean diets. Lifesum's premium subscription unlocks additional features like detailed nutrient tracking, advanced analytics, and a vast library of healthy recipes.
In June 2024, Lifesum announced its transformative acquisition of LYKON, a leading biomarker-based personalized nutrition company in Germany. This strategic move aims to revolutionize Lifesum's service by integrating LYKON's pioneering technology, enabling users to access personalized nutrition and wellness recommendations based on medical-grade biomarker testing and analysis.
Key customers and partnerships
Lifesum has forged several notable partnerships to enhance its offerings and reach. In 2024, the company collaborated with Amazon to integrate its services with the Amazon Halo fitness tracker. Additionally, Lifesum partnered with Strong by Zumba, a prominent health club chain, further expanding its corporate customer base, which already includes over 100 companies as of June 2024.

Lifesum

Season Health is a food-as-medicine platform that offers personalized nutrition solutions to manage chronic conditions. Its services include tailored meal plans, pre-made meals, grocery support, one-on-one consultations with registered dietitians, and nutrition education. Season Health caters to payers and employers, addressing the growing prevalence of preventable chronic diseases linked to poor dietary habits. The company's approach involves translating clinical guidance into affordable, often subsidized food options integrated with payer benefits.
In November 2023, Season Health strategically acquired clinical assets from Wellory, expanding its provider network from dozens to hundreds of registered dietitians. This acquisition enabled Season Health to offer its services to Aetna and Cigna members, adding to its existing partnerships with UnitedHealthcare, Blue Cross Blue Shield of Arizona, and Geisinger. Season Health's technology platform supports health plans, providers, and employers seeking to implement food-as-medicine programs or leverage its marketplace solutions.
Season Health's evidence-based clinical nutrition programs have proven effective in improving health outcomes and reducing total cost of care. A recent report on the company's diabetes program revealed that members with an HbA1c level at or above nine points lowered their levels by an average of 1.8 points within 90 days of engaging with Season Health's registered dietitians and related clinical program.

Season Health

Providers of tailored dietary recommendations based on an individual's genetics and lifestyle for optimal wellness and disease prevention. This also includes calorie-counting apps that assist with weight loss and management

Designers of tailored dietary plans to address root causes of chronic diseases and symptom management

Companies that develop and offer supplements and nutraceuticals focused on enhancing health, addressing nutrition deficiencies and supporting overall wellness

Companies that provide personalized food services, including medically tailored meals and a marketplace for diverse dietary products to meet individual needs

Companies that offer virtual consultations from dietitians and nutritionists offering guidance via personalized nutrition plans, lifestyle and dietary assessments, and a focus on long-term health and wellness

Most functional nutrition companies offer nutrition solutions via digital mediums such as mobile applications; virtual consultations are also a part of the industry

Some functional nutrition offerings are based on the genomic profiles of individuals to identify personalized solutions

The products/platforms offered by most companies utilize AI/ML to enhance their offering

Most functional nutrition companies provide personalized nutrition solutions in the form of meal plans, supplements, and prepared meals

Limbo

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