FogPharma is a biopharmaceutical company engaged in developing a novel class of therapeutics known as Helicons. These drugs aim to bridge the capabilities of antibodies and small molecules, targeting proteins traditionally deemed undruggable due to their cellular locations or structures. FogPharma's key product, FOG-001, is a TCF-blocking β-catenin inhibitor. As of April 2024, it was in Phase I/II clinical trials, focusing on various solid tumors by disrupting the Wnt/β-catenin signaling pathway, which is implicated in many cancers.
Key customers and partnerships
FogPharma’s key stakeholders are in the healthcare and pharmaceutical sectors, particularly those focusing on oncology and hard-to-treat diseases.
Funding and financials
In March 2024, FogPharma raised USD 145 million in a Series E funding round led by Nextech Invest with participation from other investors such as RA Capital Management, Rock Springs Capital, and General Catalyst. The proceeds were aimed at advancing the clinical development of FOG-001 and enhancing the company's portfolio of Helicon Peptides.
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