TiE SoCal Angels is a network of successful entrepreneurs, professionals, and highly educated individuals who are now turning their passion for business into investments and mentorship for the next generation.

TiE SoCal Angels

FundRx is a healthcare venture capital firm and platform.

FundRx

F-Prime's roots are in one of America’s great entrepreneurial success stories. Fidelity Investments was founded in 1946 and grew from a single mutual fund into one of the largest asset management firms in the world, with over $2 trillion in assets under management. For the last forty years, this venture capital group has had the privilege of backing other great entrepreneurs as they built ground-breaking companies in technology and life sciences, including Atari, MCI, ROLM Corp., Alibaba, Ironwood Pharmaceuticals, and Ultragenyx.  Today, F-Prime's funds are larger and more global, but its teams are still small and local. F-Prime stays true to its entrepreneurial roots. In the US and Europe, F-Prime Capital Partners is investing in healthcare (formerly Fidelity Biosciences) and in technology (formerly part of Devonshire Investors). In other geographies, its sister fund is called Eight Roads (formerly Fidelity Growth Partners), with investment teams in London, Shanghai, Beijing, Hong Kong, Tokyo, and Mumbai.   Together F-Prime brings a world of insight, domain expertise and relationships to support entrepreneurs. Without the pressure of fundraising from outside investors, F-Prime Capital Partners focuses all of its time finding and helping great entrepreneurs build important companies.

F-Prime Capital

Optum Ventures provides capital and strategic guidance to startup companies solving health care's pressing challenges. It is the venture capital investment arm of Optum that invests in digital health companies that use data and insights to help improve consumers' access to health care services and how care is delivered and paid for, and that makes the health care system more reliable and easier to navigate.

Optum Ventures

Humana creates innovative solutions and resources that help people with their healthcare needs. The company is an innovator with a commitment to service, health, and wellness. Their focus on people, choice, engagement and innovation guides our business practices and decision-making. In addition to group health plans, Humana's diverse lines of business work to serve all types of consumers. Humana was founded in 1964 and is based in Louisville, Kentucky, United States.

Humana

Cigna Ventures is the arm venture of Cigna, that accelerate growth of start ups in health care industry. The company's mission is to accelerate Cigna’s ability to improve the health, well-being and sense of security of the people we serve by partnering with and investing in innovative companies, and delivering differentiated value in the marketplace. It focuses on harnessing transformative ideas in insights and analytics; digital health and retail; and care delivery and management.

Cigna Ventures

MBX Capital is a venture capital partnership investing in early-stage healthcare and life sciences companies.

MBX Capital

WR Hambrecht is a financial services firm that helps companies of all sizes access capital at the lowest cost in order to accelerate disruptive growth. Its philosophy is based on tenants such as identifying companies, helping them raise capital and go public, and delivering market pricing. The company has a wide range of products such as the OpenIPO Auction, the A+ IPO, the OpenBook Auction, and the OpenFollowOn Auction. Their clients are NETSUITE, Google, MORNINGSTAR, and XBiotech and it also offers initial public offering services to companies. WR Hambrecht is a U.S.-based company that was founded in 1998 by William and Robert Hambrecht.

WR Hambrecht

Trustbridge is a growth-oriented private equity firm with offices in Boston, Shanghai, and Hong Kong. The firm invests globally in innovative, high quality growth opportunities in various stages across Technology, Healthcare and Media. Founded and managed by entrepreneurs and operators, Trustbridge provides patient, long-term capital and partners with management teams building products and services that improve lives globally. Utilizing a growing, global portfolio and deep operational expertise, the firm has a particular focus on helping its portfolio companies enter new international markets, including China.

Trustbridge Partners

Buoy Health

Buoy provides a personalized all-in-one platform to help guide consumers back to health. Whether it's chatting about symptoms with Buoy Assistant to get help in the moment of sickness or researching benefits through Buoy Dashboard, Buoy is available 24/7 to help make self-diagnosis and navigating the healthcare system simple and easy. For employers, Buoy can be custom configured to surface benefits information and wellness programs, guide employees to in-network providers, and fully integrate with other health portals.  The company was founded in 2014 and is headquartered in Boston, Massachusetts.

<div><p>Buoy Health is a healthcare service that helps patients connect with healthcare providers covered by their health insurance to help analyze symptoms. The company aims to keep people from using internet searches to diagnose their health issues and direct patients to appropriate care before conditions escalate. Patients can interact with a health assistant that leverages AI tools to help patients reach a diagnosis and triage to the appropriate care. The company also has a business-to-business (B2B) offering, targeting employers to reduce healthcare costs.</p></div>

More important now than ever, telehealth will long outlast the pandemic that drove its growth.

Telehealth

<div>
  <p>
    Buoy Health is a healthcare service that helps patients connect with healthcare providers covered by their health insurance to help analyze symptoms. The company aims to keep people from using internet searches to diagnose their health issues and direct patients to appropriate care before conditions escalate. Patients can interact with a health assistant that leverages AI tools to help patients reach a diagnosis and triage to the appropriate care. The company also has a business-to-business (B2B) offering, targeting employers to reduce healthcare costs.
  </p>
  <p>
    In November 2020, the company raised USD 37.5 million in Series C funding, bringing the company&rsquo;s total funding to USD 68.2 million. The new funding is expected to be used for expanding artificial intelligence (AI) and tech features, improving its clinical and insurance navigation capabilities, and increasing its workforce.
  </p>
</div>


<div>
  <p>
    Nice Healthcare is a US based telehealth company with a focus on primary care services to business-to-business (B2B) clients. Once the employer signs its employees with Nice (at a cost of USD 30 to USD 36 per employee per month), employees do not have to incur out of pocket expenses for Nice services and can schedule virtual or home visits within the time frames specified by the company. It connects patients with practitioners through a mobile app over video calls or text messages. Members can also request home visits which will be completed within a few hours, as claimed by the company. As of March 2022, Nice was operating in twelve states, and had over 400 small and medium enterprises (SMEs).
  </p>
  <p>
    In March 2022, the company raised USD 30 million in Series A financing led by DNA Capital which has been earmarked to expand its platform&rsquo;s reach among small and medium businesses. Additionally, the company is hiring three members for its management team to support the continuing growth of the organization.
  </p>
  <p>
  </p>
</div>


Nice Healthcare

<div>
  <p>
    Amicomed is a cloud-based Software-as-a-Service (SaaS) platform which provides blood pressure monitoring services. It collects blood pressure data of patients from at-home devices, applies algorithms, and assesses the fluctuations in the blood pressure. Physicians can be connected and provided with blood pressure data of their patients in order to facilitate their workload, enabling more personalized management of patients regarding medication and lifestyle indications. 
  </p>
  <p>
    Amicomed can also recommend actionable and personalized lifestyle interventions such as daily diet and exercises via virtual coaching.
  </p>
</div>


Amicomed

<div>
  <p>
    Winston is a men&rsquo;s health telemedicine platform that treats common issues impacting men such as sexual problems, hair loss, acne, and cold sores. Winston allows patients to consult doctors, place orders for prescription drugs, and offers free delivery to the homes of patients. 
  </p>
  <p>
    The Toronto-based company aims to avoid men deferring doctor visits or withholding sensitive information. The consultation fee is covered by the provincial health plan, but the prescriptions are billed to the customer.
  </p>
</div>


Winston

<div>
  <p>
    Eko Health is a cardiopulmonary digital health company that aims to improve heart and lung care for patients using sensors and artificial intelligence. The company produces connected handheld digital stethoscopes with electrocardiogram functionality to detect heart rhythm abnormalities using artificial intelligence (AI) algorithms. In 2020, the company obtained 501(k) FDA clearance for multiple algorithms that help detect heart murmurs and atrial fibrillation, or AFib. These algorithms were used in 2022 to develop the Eko App, which pairs to the company's stethoscopes for report generation, information sharing and carrying out examinations. 
  </p>
  <p>
    The company operates on a fee per unit B2B2C model and a D2C model, where it provides its technology to medical practitioners or patients for diagnostic purposes.
  </p>
  <p>
    In February 2023, Eko 
    <a href="https://sp-edge.com/updates/16677">
      launched SENSORA
    </a>
    , a cardiac disease detection platform that combines the company&rsquo;s existing digital stethoscopes with a machine learning-based platform. The platform enables primary care physicians to detect structural murmurs and assess heart arrhythmias by using a database of heart sounds to compare and identify anomalies in a patient's heart beat. 
  </p>
  <p>
    In April 2024, Eko 
    <a href="https://sp-edge.com/updates/28111">
      obtained FDA 510(k) clearance
    </a>
     for its AI-aided cardiac tool, Eko Low Ejection Fraction Tool (ELEFT). The tool is designed to assist providers in early detection of low ejection fraction, a significant sign of heart failure.
  </p>
  <p>
    <b>Funding and financials</b>
  </p>
  <p>
    In March 2022, raised a further USD 30 million in an extension to its Series C round, which began November 2020. The total funds raised by the company stood at USD 126 million as of March. These funds have been allocated to support further commercialization efforts and develop new products for the company.
  </p>
  <p>
  </p>
  <p>
  </p>
  <p>
  </p>
</div>


<div>
  <p>
    Dialogue partners with employers and health insurers to offer telehealth services to their employees and members. The users have 24/7 access to doctors, nurses, and other healthcare professionals via audio, video, and chat options for wide arrays of physical and mental health needs, artificial intelligence-enabled (AI-enabled) triage, referrals, and prescription renewals. 
  </p>
  <p>
    The company launched its trademarked Integrated Health Platform in January 2021 to consolidate its virtual care,  wellness programs, mental healthcare services, and Employee Assistance Program (EAP) onto a single platform. The company claims to be the only integrated health and wellness B2B platform in Canada. 
  </p>
  <p>
    <b>Key Customers and partnerships</b>
  </p>
  <p>
    Dialogue had direct relationships with over 2,000 customers across Canada and Germany as of December 2020 and served around 50,000 organizations through these partnerships. In addition, the number of members with access to the virtual platform topped 1 million in January 2021. 
  </p>
  <p>
    <b>Fundings and financials</b>
  </p>
  <p>
    As of March 2021, Dialogue was planning to raise CAD 100 million (USD 80 million) from an initial public offering that will be listed on the Toronto Stock Exchange under the ticker symbol &ldquo;CARE.&rdquo; 
  </p>
  <p>
    In Q2 2023, net losses reduced significantly YoY to CAD 5.8 million (USD 4.3 million) from CAD 8.4 million (USD 6.3 million) in Q2 2022. Top-line revenue met internal expectations, growing 17.2% YoY to CAD 25.5 million (USD 19.0 million), driven by &nbsp;an increase in new members (by 18.6% YoY), 
    an expansion of the attach rate as existing customers added more services, and full-quarter contributions from Tictrac.
     
    Dialogue Health has not provided any forward-looking guidance as the company has entered into an agreement to be 
    <a href="https://investors.dialogue.co/English/news/news-details/2023/Dialogue-to-be-Acquired-by-Sun-Life/default.aspx">
      <u>acquired by financial services company Sun Life Financial</u>
    </a>
     for a consideration of CAD 365 million (USD 270 million) or CAD 5.15 (USD 3.82) per share. The transaction is expected to close in Q4 2023. Post acquisition, Dialogue will delist from the Toronto Stock Exchange but will continue to operate as a standalone entity under the &ldquo;Sun Life Canada&rdquo; brand from its head office in Qu&eacute;bec. 
  </p>
  <p>
  </p>
</div>


Dialogue

IoT is used by most telehealth providers to operate virtual services

All telehealth players are involved in digital health via virtual offerings

Industry players offer varying degrees of personalization for each target audience

Some players offer technology and platforms to healthcare providers, converting physical-only services into virtual services

Specific telehealth offerings focus on diversity and inclusion, providing care to LGBTQ+ or BIPOC populations

Generative AI is used to streamline administrative tasks such as clinical note-taking

Primary care through virtual consultations for general health-related concerns using a digital platform or mobile app. 

Buoy Health

Telehealth

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