Hartmann Capital is a frontier-tech investment firm, seeking out opportunities that produce global paradigm shifts, such as Digital Assets, VR/AR, AI, space, and transhumanism.  In early 2018, Hartmann Capital launched its inaugural long-biased, multi-strategy crypto asset hedge fund, Hartmann Digital Assets. The fund is renown for its long/short, thematic, event-driven, and activist investing in the digital assets ecosystem.  Since 2020, Hartmann Capital runs a pure prop arm, Hartmann Ventures, which has has made long term investments in both digital assets and spacetech (Starbridge, Space Capital, Axiom, Lynk) In October 2021, Hartmann Capital launched its second fund, Hartmann Metaverse Ventures I, a pure metaverse venture fund, focused on investing into the infrastructure, content, and access points of the metaverse.

Hartmann Capital

Mayfield is a global venture capital firm with a people-first philosophy and a 50+ year track record of inception and investing, partnering with founders to build iconic enterprise, consumer, and engineering biology companies. Since its founding, the firm has invested in more than 500 companies, resulting in 119 IPOs and more than 200 acquisitions, and currently has $2.5B under management.

Mayfield Fund

Vine Ventures is a venture capital firm that explores unique business models in life sciences. The firm was established by founding General Partner Ryan Zurrer.

Vine Ventures

Presence Capital is an investment firm that believes virtual reality (VR) and augmented reality (AR) are technologies that are going to transform our world. We invest in and support talented and passionate entrepreneurs that are utilizing these technologies to bring new and exceptional ways of communicating, working, and playing to market

Presence Capital

Grit Ventures is leading pre-seed and seed stage investments and bringing a smart money model to Deep Technology early stage investing. Sourcing from the leading nationwide labs and leveraging over 3 decades of Go-To-Market experience in Hardware, Grit invests in and shepherds groundbreaking AI + Robotics + Clean Energy companies through the often tumultuous journey from Labs to Launch.

Grit Ventures

Evolution Ventures is an early-stage venture capital fund dedicated to investing in startup companies with purposeful founders who want support in leadership and in developing their organizations so as to rapidly scale without losing their soul, serving all their stakeholders as they do.

Evolution Ventures

We provide early-growth stage capital to transformational venture-backed technology businesses.We believe in partnering with the very best entrepreneurs and top-tier early-stage investors to help build enduring technology companies. We operate under the premise that the only way to build a world class business is to always put the company first. We believe this ethos optimizes outcomes for our companies and Limited Partners alike.

Beni VC

What If Ventures invests in stigmatized verticals within the healthcare market. For too long, stigma has artificially suppressed demand for care in indications such as mental health, fertility, and many others.  Societal changes are creating markets where stigma once stood in the way of people getting the care they need. The firm was founded in 2019 by Stephen Hays, after his own personal struggles with mental health and addiction fueled his desire to see more funding for solutions in that space.  Since then, the firm has broadened its aperture and has deployed nearly $80mm into more than 60 disruptive healthcare startups.

What If Ventures

Alpha Bridge Ventures invests in post seed stage companies and the personal development of their founders.

Alpha Bridge Ventures

Lionheart Ventures is a global, seed-stage venture capital firm focused on mitigating civilizational risk. We do this by supporting the wise development of transformative technologies. Our main areas of investment focus are transformative artificial intelligence and frontier mental health technologies. Leading academics estimate a 1-in-6 chance of human extinction by the year 2100, largely driven by risks from emerging technologies. And now, with the exponential growth of AI, predictions are getting worse. Our startups are part of the solution. We invest in exceptional, ethical founders who are developing transformative technologies that have the potential to impact humanity on a meaningful scale, while generating attractive returns for our LPs.

Lionheart Ventures

Europe's first venture capital firm to focus solely on investments into psychedelic healthcare companies. Ten investments already executed with more in the pipeline.

Neo Kuma Ventures

Incisive Ventures is a pre-seed investor focused on transformational founders. They invest in low-cost investment vehicles that boost LP returns in the asset class, especially compared to the classic Venture model. The company is a theme syndicate with high conviction but low volume.

Incisive Ventures

Inflect Health is Optimized and accessible for all.

Inflect Health

JLS Fund is a venture capital firm that invests in the psychedelics and technology intersection.

JLS Fund

re.Mind Capital is the mental health VC arm of serial entrepreneur and investor Christian Angermayer and his family office Apeiron Investment Group.

re.Mind Capital

Iter Investments is a venture capital firm that seeks to invest in companies operating in the mental health sector. It partners primarily with early-stage private companies operating across the psychedelic ecosystem. They assist entrepreneurs and management teams to build great companies that will transform the mental and behavioral health industry.

Iter Investments

Psymed Ventures is an investment syndicate that invests in early-stage psychedelics companies. The firm was founded in 2020 by Matias Serebrinsky and Dina Burkitbayeva and is headquartered in San Francisco, California, United States.

PsyMed Ventures

Red Beard Ventures is a full-stack web3 fund investing across Web 3.0 and crypto, including consumer applications, infrastructure, gaming, the metaverse, and DeFi with a focus on pre-seed through Series B investments in equity and tokens.

Redbeard Ventures

CTR Capital is raising capital for The Conscious Capital Fund, which is empowering mission-oriented founders, involved in explosive growth sectors striving to positively impact a billion+ lives, by raising human consciousness as an effort to solve humanity's problems. They are currently exploring some of the key areas for possible investment in the convergence of disruptive health, fintech, psychedelic research and products, mental health, sustainable civilization, human augmentation, meditation, and transformative education.

CTR Capital

BITKRAFT Ventures was founded in 2015 by german serial entrepreneur, Jens Hilgers. BITKRAFT’s team is located in Berlin, Los Angeles, San Francisco, New York, London, Madrid and Lisbon covering videogames and esports investments not only digitally but in the most relevant and busy metropoles for digital entertainment in the Western world.

BITKRAFT Ventures

Qualcomm is an American fabless semiconductor company that designs, manufactures, and markets digital wireless telecommunications products and services. It produces processors and connectivity solutions, displays, software, and charging products. The company is focused on various industries: automotive, education, healthcare, Internet of Everything, mobile computing, networking, smart cities, smart homes, and wearables. Qualcomm’s products include Gobi, Hy-Fi, IPQ, IZat, Powerline, Snapdragon, Small Cells, VIVE, Wi-Fi platforms, Mirasol, Pixtronix, AllPlay, 2net, Brew, HealthyCircles, QChat, QLearn, RaptorQ, Vuforia, Halo, and WiPower.

Qualcomm

HTC Corp is engaged in the design, development, and manufacture of smartphones and tablets in Taiwan.   The company offers PDA phones and smartphones for mobile operators and distributors in Europe, the United States, and Asia. These machines are available as HTC devices and as products individually customized for operators and device partners. The company provides its own HTC self-branded products as well as supports operator-branded products and original equipment manufacturer (OEM) partners. It owns Dopod as a subsidiary company and is a member of the Open Handset Alliance.   The company’s products are sold under various brand names such as HTC, Dopod, and Qtek and are often rebranded by major telecommunication carriers. Its products also include pocket PC phones (PDA Phone), ultra mobile phones, HTC kovsky (Sony Ericsson XPERIA X1), and HTC dream (T-mobile G1).   HTC Corp was founded by Cher Wang and Peter Chou in 1997. It is headquartered in New Taipei City, Taiwan.

Niantic’s mission is to use emerging technology to enrich their experiences as human beings in the physical world. They seek to build products that inspire movement, exploration, and face-to-face social interaction. Originally formed at Google in 2010, they are now an independent company with a strong group of investors including Nintendo, The Pokémon Company, and Alsop Louie Partners. They’re focused on building games that get people outside and exploring by enabling their players to have fun while visiting new places, learning about the world around them, and meeting new friends. They’ve launched Ingress, an immersive real-world mobile game played by millions of people; it's been downloaded more than 20 million times and is played in over 200 countries and territories worldwide. They've also developed Pokémon GO, which has broken records around the world and has been downloaded more than 750 million times in its first year.

Niantic

The Amazon Alexa Fund is Amazon’s venture capital fund investing in artificial intelligence, frontier tech, voice, robotics, and digital health across consumer and enterprise. We invest in early- to growth-stage companies globally. To learn more, visit us at alexafund.com.

Amazon Alexa Fund

Grit Capital Partners invests in high potential entrepreneurs who seek to disrupt industries with technology and data, and are on a path to change the world.  The combination of a powerful idea, an addressable market, and a world class team provides significant advantage when combined with their powerful network of entrepreneurs, executives, and technology veterans at the top of their game.

Grit Capital Partners

TRIPP

Equa Health is a personalized meditation training technology. We are currently delivering our hybrid training program to select B2B clients seeking to build a happier and more engaged workforce.

TRIPP is a digital psychedelic wellness platform that uses the power of virtual and augmented reality. TRIPP creates advanced digital products that are based on scientific research and delivered through virtual reality, augmented reality, and mobile devices. TRIPP's platform is currently delivering wellness solutions to consumer households. It was founded in 2017 and headquartered in Los Angeles, California.

California-based Tripp is a meditation and mindfulness app that provides wellness solutions in the form of guided meditations and personally curated mindfulness exercises, to improve focus, concentration and enhance mental wellness.

A new industry proving that digital connectivity and mental health can co-exist.

Digital Wellness

<div>California-based Tripp is a digital psychedelic startup that provides wellness solutions in the form of guided meditations and personally curated mindfulness exercises, to improve focus, concentration and enhance mental wellness.&nbsp;</div>

Promising research and receding stigma are giving investors cannabis-boom flashbacks.

Psychedelic Medicine

TRIPP offers a digital wellness platform focused on meditation. The company launched its VR meditation app in 2019, now accessible across a range of headsets (the Meta Quest, HTC Vive, Apple Vision Pro, Pico and the Sony PSVR 2). Types of meditations offered include Focus (to sharpen attention and present-moment awareness), Ascend (a psychedelic research-driven experience), Escape (immersion in natural landscapes), Calm and Sleep. Notably, immersive meditative experiences on the platform were developed by award-winning creators formerly from Amazon, Disney, EA, and Grammy-nominated music artists. Other platform features offered include AI-powered breath detection, binaural sound frequencies and gamification elements.

Technologies bringing about a new reality

Extended Reality

TRIPP Brings Award-winning Wellness Experiences to Apple Vision Pro

Equa Health

TRIPP offers a digital wellness platform focused on meditation. The company launched its VR meditation app in 2019, now accessible across a range of headsets (the Meta Quest, HTC Vive, Apple Vision Pro, Pico and the Sony PSVR 2). Types of meditations offered include Focus (to sharpen attention and present-moment awareness), Ascend (a psychedelic research-driven experience), Escape (immersion in natural landscapes), Calm and Sleep. Notably, immersive meditative experiences on the platform were developed by award-winning creators formerly from Amazon, Disney, EA, and Grammy-nominated music artists. Other platform features offered include AI-powered breath detection, binaural sound frequencies and gamification elements.In <a href="https://sp-edge.com/updates/32054">July 2024</a> Tripp launched Kōkua XR in beta, an AI meditation guide for personalized wellness experiences. The app provides individualized meditative reflections based on real-time user feedback. Users can speak and have the app leverage a large language model (LLM) to receive meditation guidance.&nbsp;The company generates revenue using monthly subscriptions priced at USD 10 (for its VR app, and AI meditation guide individually).In February 2022, the company acquired EvolVR, claimed at the time to be the world’s largest live meditation community in VR, with over 40,000+ users.Key customers and partnershipsAs of February 2024, the company hosted over 9.7 million wellness sessions on its platform, up from 6 million in October 2022. At the time, the company stated that 43% of TRIPP’s active monthly users used TRIPP at least 2-3 times a week.In January 2023, TRIPP partnered with mindfulness training app Equa Health to develop the platform's first clinically-backed experiences for mindfulness training.Competitors: None under a similar stage.

Interplay Learning (Interplay) provides on-demand, interactive, and hands-on simulation learning courses for skilled trades, including HVAC, plumbing, electrical, solar, and facilities maintenance, through VR, mobile, and desktop applications. The learning courses also include simulated walkthrough videos where experts lead users through procedure guides methodically, with knowledge testing features and additional learning material such as wiring diagrams, equations, sample system configs, and charts at the end of each lesson. The platform also enables managers to track user progress.The company operates a subscription-based model with monthly packages for individuals (USD 54) and teams (USD 229), alongside a custom plan for larger organizations.In <a href="https://sp-edge.com/updates/33810">September 2024</a>, the company acquired Industrial Training International (ITI), enabling the company to provide immersive simulation training solutions for crane and rigging operations across various job sites.Key customers and partnershipsNotable customers include Tesla and Rheem Manufacturing. Interplay’s customer usage rose by 445% YoY in 2020. As of February 2021, the platform had over 2,000 customers and 110,000 users across the US.

Interplay Learning

Switzerland-based WayRay develops holographic AR technology and hardware for the automobile sector. Its technology is used in head-up displays (HUDs) that project images into a driver’s field of vision to assist with navigation. Although its initial focus was on developing HUDs that can be purchased and installed in any vehicle, it has since pivoted to producing embedded HUD systems (i.e., hardware built into vehicles). WayRay’s HUDs are considered to provide a wider field of vision and combine data (location and mapping information) with vision data to generate images by projecting a laser beam through a Picture Generating Unit (PGU) onto a Holographic Optical Element (HOE).&nbsp;In <a href="https://sp-edge.com/updates/18537">May 2023</a>, WayRay announced integration of its AR displays into Tesla Model 3's in Switzerland, with plans to follow shortly afterwards in the US. Previously, in September 2021 the company launched its deep reality system that replaces the traditional car dashboard. In addition, WayRay launched “The Holograktor” dubbed the first “metaverse on wheels”, which can be driven conventionally or using a remote control via a 5G and satellite connection (November 2021).&nbsp;The company’s founder and CEO, Vitaly Ponomarev, identified that its systems are more advanced, backed by more patents, and potentially 20x smaller than comparable devices in the market. WayRay’s HQ in Switzerland also acts as a product design and development hub, while its R&amp;D center and prototyping factory are based in Russia.&nbsp;Key customers and partnershipsThe company is backed by strategic investors such as luxury automaker Porsche, which highlighted the management’s expertise in space engineering, hardware, and software development as key reasons for its investment, Hyundai Motor Co., and Alibaba. It is also notable that these investors, particularly Hyundai, are looking at ways to potentially use WayRay’s technology to offer more services in the future. For instance, Hyundai believed that the technology could be used for smart cities and smart buildings, which are its new areas of interest.WayRay partnered with Karma Automotive, a producer of luxury electric vehicles, in December 2021 to support the implementation of its HUDs into their test fleet. Moreover, it partnered with a leader in designing and manufacturing specialty glass, AGP eGlass, in September 2021 to further proliferate its technology.&nbsp; Funding and financialsIt was reported in April 2021 that the company is considering a public listing at a USD 2 billion valuation via a SPAC, although no further updates on this have been announced as at January 2024.&nbsp;

WayRay

AmazeVR initially focused on developing VR technologies but pivoted to VR concerts in late 2019. The concerts are backed by proprietary 9K cameras and software that automate complex VR concert visual effects that run on more than 100 headsets simultaneously. Users join and hang out with other users as avatars while experiencing VR concerts. It intends to bring VR concerts by major artists to theaters and eventually, homes.AmazeVR rolled out its first commercial VR concert, which will feature 3x Grammy winner Megan Thee Stallion, in 2022. The artist is expected to tour select AMC Theaters across the US. It is also in the final stages of closing deals with its second and third artists. AmazeVR also revealed plans to release weekly content by 2024 in theaters and for at-home viewers.In <a href="https://sp-edge.com/updates/20145">July 2023</a>, AmazeVR launched its official AmazeVR Concerts app, featuring an exclusive VR concert from Swedish pop star, Zara Larsson. The app is available on major VR app stores, and the exclusive Zara Larsson VR concert can be accessed for a year at a launch price of USD 6.99. AmazeVR also produces and monetizes VR content on a subscription basis.As of August 2023, the company was in the process of producing and releasing mixed reality concerts by overlaying virtual elements onto live, real-world video.Funding and financialsThe company’s most recent funding was in <a href="https://sp-edge.com/updates/13338">September 2022</a>, when it raised USD 17 million in a Series B funding round led by Mirae Asset Capital. The fresh funds were allocated to expand partnerships with artists, artist management companies, labels, publishers, and agencies.

AmazeVR

Dispelix, based in Finland, designs and manufactures single-layer, full-color waveguide displays, a thin (about 1mm) transparent element that takes in a projected image and relays it to the eye, using a nanophotonics-based approach catering to AR applications (e.g., smart glasses). It uses laser beam scanning technology to render laser-sharp images with a gamut of color palettes, which are displayed using beam-combiner technology. Its patented and proprietary approach includes diffractive surface relief gratings, which are elements used for high-power laser applications, fabricated on high refractive index glass wafers that enhance field-of-view and image quality.The company had a total of more than 40 granted or pending patent families as of November 2021. Its product line, Dispelix DPX, includes Dispelix DPX - Ohut, Dispelix DPX - Selva, and Dispelix DPX - Sade with a varying degree of field of view, form factor, and weight. According to Co-Founder and CTO Juuso Olkkonen, its displays are the lightest and thinnest in the market.Key customers and partnerships 1) Collins Aerospace: to integrate Dispelix's advanced AR displays into Collins Aerospace's products (November 2024)2) Foxconn and Pegatron: to create reference designs for AR glasses based on its Selvä waveguide display (October 2023)&nbsp;3) VividQ: created a “waveguide combiner” which accurately displays variable-depth 3D content in a user’s environment (January 2023)4) ColorChip and Maradin: To further Light Beam Scanning (LBS) solutions for AR glasses (October 2022)5) Jade Bird Displays: To develop multiple reference designs for AR devices (June 2022)6) AAC Technologies: To improve waveguide displays for the AR and MR industry (March 2022)7) OQmented: for the development and commercialization of MEMS-based LBS technology (November 2021)8) Coretronic: To develop a range of AR optical module solutions (December 2020)9) Hoya Corporation: To improve quality of waveguide displays (November 2020)Funding and financialsIn its most recent funding round (November 2021), Dispelix raised USD 33 million in a Series B funding round co-led by Atlantic Bridge, CCB Trust, and Flashpoint with participation from Lifeline Ventures, VTT Ventures, and 3M Ventures. The funds were allocated to product development. It revealed that several OEM customers were slated to integrate its technology into their consumer offerings by 2023.&nbsp;

Dispelix

DigiLens is a developer of holographic waveguides, which is a clear, thin piece of glass or plastic, used for AR devices. In January 2023, the company launched ARGO, an XR smartglass designed for enterprise and industrial use, the first AR device to utilize Qualcomm’s SnapDragon XR2 platform. Other specifications included 6-degrees of freedom (6-DoF) tracking, a 30-degree field-of-view, spatial audio, a 48MP RGB camera, voice and gaze recognition, access to real-time data visualizations, and a 2,500-nits HD display.&nbsp;The company’s first product, the DigiLens Crystal was introduced in 2019, was a thin-film laser-etched photopolymer embedded with microscopic holograms of mirror-like optics. By projecting a micro display to one end of the lens and another set of optics working to guide the light wave toward the eye, this proved to be an ideal piece of hardware for AR devices, which are preferred with as little hardware as possible.&nbsp;It claims that its patented optical platform and photopolymer technology coupled with a holographic copy manufacturing process enable it to produce cheaper and more scalable solutions. In <a href="https://sp-edge.com/updates/17598">April 2023</a>, the company announced the launch of SRG+, a surface relief gratings product that improves upon its waveguide technology.The company generates revenue by licensing its technology across a range of industries including the automobile, enterprise, consumer, avionics, and military sectors. DigiLens also offers a white-label solution for automotive companies whereby it creates holographic waveguides for windshields that could offer in-cabin experiences for drivers.&nbsp;&nbsp; Key customers and partnershipsKey partnerships include that with1) Phantom Technologies: - Phantom Technology: To integrate Phantom's CASSI Spatial AI assistant into the DigiLens ARGO glasses, providing features such as spatial search, a contextual assistant, and task management using voice commands (October 2023)2) Wisear: To integrate its neural interface-powered earphones with the ARGO smart glasses (May 2023)3) Mojo Vision: To utilize Mojo Vision's micro-LED technology to build improved AR glasses (May 2023)4) Taqtile: To integrate the company's ARGO smart glasses with Taqtile's AR work platform, Manifest (May 2023)5) OMNIVISION: To develop new XR product offerings (January 2023)Other partnerships include that with OMNIVISION (January 2023), a leading global developer of semiconductor solutions to develop new XR product offerings. OMNIVISION’s liquid crystal on silicon (LCOS) panels allowed DigiLens to build LCOS/LED projectors optimized for its holographic waveguides. OMNIVISION's core camera technology provides DigiLens' devices with features such as visual odometry and six degrees of freedom.&nbsp;DigiLens also works with Taiwanese licensed waveguide manufacturer Young Optics, Chinese original design manufacturer and electronics supplier Malata, Korean display manufacturer Sekonix, international technology company Continental, Chinese optical elements manufacturer Crystal Optech, and Mitsubishi Chemical.&nbsp;Funding and financialsIn April 2022, DigiLens announced the second close of its Series D funding round (intiial close in November 2021) in which it raised USD 50 million at a valuation of USD 530 million. The funds were allocated for the development of DesignV1, its second-generation product.

DigiLens

Companies developing XR headsets and relevant sub-components (displays, sensors, and processors). Also includes complementary XR hardware (tracking devices, haptic vests, and gloves)

Companies offering engines that enable the development of AR/VR content, also includes companies offering capabilities to capture and create 3D images for immersive environments

Companies offering AR/VR solutions or toolkits for specific industry applications, including VR game developers

Companies offering location-based AR/VR experiences

AR/VR platforms offer remote assistance to field experts and headset manufacturers facilitate virtual work

Some solutions in the "content" segment are offered under a B2B SaaS model

Headsets and content segments provide the building blocks for the metaverse

AR, VR, and MR are the primary enabling technologies for the XR industry

California-based Tripp is a meditation and mindfulness app that provides wellness solutions in the form of guided meditations and personally curated mindfulness exercises, to improve focus, concentration and enhance mental wellness.The app uses VR &amp; AR to deliver psychedelic visual and audio experiences, similar to what people experience during a psychedelic trip, without the use of psychedelic drugs. Tripp caters directly to consumers and also through employer benefit plans. It is also researching non-chemical, digital methods to tackle mental health issues including several clinical trials to understand the effectiveness of the Tripp platform as a therapeutic device to treat anxiety, depression, and substance use disorders.With the acquisition of PsyAssist, a digital startup that provides support to conduct psychedelic-assisted therapies, the company entered the psychedelic space in August 2021. It will jointly launch a new product called the “TRIPP PsyAssist” to provide step-by-step guidelines for psychotherapists and patients before, during, and after therapies.Tripp’s session only takes a few minutes to complete and has been reported by users to elevate mood by 25% on average. The company offers its app on external platforms such as Oculus and Playstation and is exploring more integrations with similar platforms to expand the user base. It also has plans to roll out Tripp in AR glasses and mobile devices soon.In June 2022, the company acquired Eden , a VR-based world-building video game created by developer BeardedEye, in order to create community-driven experiences in the mindful metaverse.In July 2024, Tripp launched Kōkua XR in beta, an AI meditation guide for personalized wellness experiences. The app was available for Quest headsets, with monthly subscriptions costing USD 9.99 and the annual subscription priced at USD 39.99 as of August 2024.Kōkua XR provides individualized meditative reflections based on real-time user feedback. Users can speak and have the app leverage a large language model (LLM) to receive meditation guidance. Other key features included mood tracking based on heart rate and breathing patterns. Key customers and partnershipsIn January 2023, the company partnered with fellow mindfulness provider, <a href="https://sp-edge.com/updates/15997">Equa Health</a>, to develop clinically validated mindfulness training modules, known as “experiences.” The extended reality training modules will cover the core areas of concentration power, equanimity (or calmness), and sensory clarity.

Headspace is a digital wellness company that delivers meditation programs through a smartphone app. The company was founded by Andy Puddicombe, a former Buddhist monk, and Richard Pierson, a marketing and brand development professional. In addition to meditation, Headspace offers stress management programs, mindfulness activities, and sleep therapy solutions. Headspace also operates a business-to-business (B2B) focused “Headspace for Work” program with around 1,600 corporate customers as of January 2021, which has seen around 3x growth during 2020. Further, the company operates “Headspace for Health,” a program that develops US Food and Drug Administration (FDA) approved meditation tools to treat chronic diseases.In November 2022, the company launched a new platform that combines its product offerings with mental health platform Ginger’s <a href="https://sp-edge.com/updates/5119">an entity it merged with in August 2021 </a>. The platform combines Headspace Health’s meditation and mindfulness services with Ginger’s on-demand coaching, therapy, and psychiatry services, to offer enterprise clients an integrated solution for supporting their employees.In September 2022, the company <a href="https://sp-edge.com/updates/12918">acquired fellow mindfulness platform Shine </a>for an undisclosed amount. The acquisition enhanced Headspace Health’s offerings and also helped grow Headspace’s member base. Select content from Shine was earmarked to be added to Headspace Health’s content library.In January 2023, the company <a href="https://sp-edge.com/updates/16052">expanded its geographical reach </a>to offer coaching, therapy, and employee assistance-related services to UK headquartered enterprise clients.&nbsp;Key customers and partnershipsAs of September 2024, the company has over 100 million users across 190 countries, with its brands “Headspace for Work” and “Ginger” being used by over 4,000 enterprises including Starbucks, Adobe, Delta Air Lines, Mattel, and Paramount. The company also partners with health plans, such as Cigna, to provide its services.In <a href="https://sp-edge.com/updates/36071">November 2024</a>, Headspace partnered with Hyatt, to help hotel guests improve their sleep quality while traveling. The collaboration featured a five-episode "Science Behind Sleep" video series filmed at Park Hyatt Aviara Resort, offering research-based tips for managing sleep struggles.In <a href="https://sp-edge.com/updates/30378">June 2024</a>, Headspace partnered with Uwill, a mental health platform for colleges and students, to integrate Headspace's wellness services into Uwill's existing portal. The collaborative effort allowed Uwill's Urise program to incorporate Headspace's services, primarily meditation, yoga, and mindfulness offerings.In <a href="https://sp-edge.com/updates/27330">March 2024</a>, Headspace partnered with Meta to launch "Headspace XR," available for an upfront fee of USD 30. Headspace XR provided guided mindfulness and meditation exercises led by the same instructors familiar to regular Headspace users. The exercises covered activities such as breathing techniques, body scans, and mood tracking. Additionally, it incorporated a social element, including interactive metaverse-style gaming in vivid environments.In <a href="https://sp-edge.com/updates/19771">June 2023</a>, the company extended its partnership with with employee benefit management platform provider Virgin Pulse to integrate its platform with Virgin Pulse’s platform. The integration enabled employees enrolled in Virgin Pulse’s health benefit offerings to access the full suite of Headspace’s offerings as a part of Virgin Pulse’s Homebase for Health platform.

Headspace

Calm is a digital wellness company which offers guided meditations to make people happy as well as mindfulness and sleep programs through a smartphone app. Its audio content is designed to strengthen mental fitness and address mental health challenges such as stress, anxiety, insomnia, and depression. The company started out as a website in 2011 where users were trained to stare at a screen and listen to waves on a beach for two minutes without touching their mouse. In February 2013, more content was added and the company launched a mobile app.&nbsp;In October 2022, the company launched a new clinical mental health offering called “Calm Health,” marking its expansion into the mental health space. The new solution provides condition-specific programs designed to bridge mental and physical care and includes tools for communication with providers and medication tracking. This solution was created for the company by Ripple Health, which was acquired by Calm in February 2022.As of 2024, Calm reported over 100 million downloads and more than 1.5 million five-star reviews. The app is available on iOS, Android, and desktop platforms. Calm operates on a freemium model with paid subscriptions unlocking full access to features. In 2023, an annual subscription cost USD 69.99, with monthly and lifetime options also available for USD 5.83 and USD 399.99, respectively. Key customers and partnershipsCalm offers content in English, Spanish, French, and German and operates Calm Business, a business-to-business (B2B) covering over 10 million employees across 3,500+ organizations as of September 2024.Calm gained significant traction in 2020 during the Covid-19 lockdowns. It became the most downloaded digital wellness app during April 2020 with 3.9 million downloads worldwide, including 1.6 million downloads in the US. Kaiser Permanente, a large managed care service provider, provided Calm free for its 12.4 million members in May 2019. Calm also partnered with CNN on the 2020 US presidential election day to play the sound of rain hitting leaves on air, a marketing effort that went viral on social media. As of September 2024, the app had 150 million+ downloads.As of December 2022, the company has partnered with over 20 brands to collaborate and provide its services through sales partnerships. These brands include Xbox, Amazon, YouTube, Adidas, Fitbit, and American Express.&nbsp;In October 2022, Calm partnered with <a href="https://news.adidas.com/partnerships/adidas-and-calm-unite-to-progress-sports-performance-through-mental-wellbeing/s/48baf8f2-f856-4313-91cf-71bf7238faea">Adidas</a> to progress sport performances through mental well-being. Another partnership is with <a href="https://www.cnbc.com/2020/10/20/lyra-partners-with-calm-to-bring-meditation-to-mental-health-service.html">Lyra Health</a> to combat stress and burnout and support resilience-building in the workplace.

Calm

<div>
 
 Simple Habit is a guided meditation service provider, which offers bite sized, five-minute long meditation sessions through an app targeting people with busy schedules. The company also offers mindfulness, sleep, and wellness programs. As of November 2020, Simple Habit offered over 2,000 sessions designed to help users sleep, reduce anxiety, and get over relationship issues. The content is organized by occasion, such as commuting, going to sleep or preparing for a meeting. 
 
 
 In June 2022 the company launched its Sleep Habit app, a virtual sleep clinic that helps users improve the quality of their sleep. The app uses clinically validated approaches to improve sleep quality and treat issues such as insomnia via methods such as cognitive behavioral therapy. 
 
 
 As of September 2022, Simple Habit claims to have a 7 million users between both of its apps. 
 
 
 
 
 In November 2018, Simple Habit raised USD 10 million in a Series A round led by Foundation Capital, bringing the company’s total funding to USD 12.6 million. The company used the funds to expand its library of guided meditation sessions and to add audio content led by therapists and executive coaches. As of late 2018, the app was reported to sign up as many as 30,000 new users per week. As of November 2020, Simple Habit reported having helped helped over five million people reduce burnout through its app’s services.
 
</div>

Simple Habit

Insight Timer is a company which offers guided meditation, yoga, and sleep programs through a smartphone app. It also offers free interactive live sessions with teachers, performers, and therapists through the app and web. The company’s business-to-business (B2B) offering, “Circles for teams”, targets enterprise customers to help bring employees together to practice group meditations, chat with each other, and recommend content. In October 2020, Insight Timer began offering free, daily live yoga classes from instructors based on a pay-what-you-can model.Insight Timer's core offering is its extensive free content library, which includes over 140,000 guided meditations, talks, and music tracks from thousands of teachers and experts worldwide. The app features a customizable meditation timer, allowing users to set session lengths and choose from various ambient sounds and ending bells.The majority of the content is available for free, and users can sign up for a premium version priced at USD 9.99 per month or USD 59.99 per year, as of August 2024. Premium users get access to content such as Insight courses and the ability to download content. This subscription unlocks additional features such as offline listening, the ability to fast-forward and rewind meditations, and access to over 1,000 in-depth courses on various topics. The app also offers live events, including yoga classes and meditation sessions, as well as a community space where users can connect with like-minded individuals and join discussion groups.Insight Timer collaborates with meditation teachers, psychologists, neuroscientists, and experts from institutions such as Stanford, Harvard, and the University of Oxford to provide content for its platform and with musicians to offer ambient and relaxation music. Insight Timer has positioned itself as a platform that supports its content creators with a revenue-sharing model that distributes 50% of course income to teachers. As of 2022, the app reported having approximately 12,000 teachers and yoga instructors contributing content to its platform. As of November 2020, the app had a 16% 30-day retention rate, more than double the average retention rate of 7.7% for top 100 apps in Apple’s App Store.&nbsp; Key customers and partnershipsThe app had over 29 million users as of September 2024. In April 2021, Insight Timer partnered with <a href="https://www.vondereurope.com/magazine/brand-partnerships-insight-timer">Vonder</a> to provide curated content, including different wellness classes and weekly group meditations. The company had also partnered with <a href="https://www.prnewswire.com/news-releases/gisele-bundchen-partners-with-insight-timer-to-encourage-millions-to-meditate-for-free-301126987.html">Gisele Bündchen</a> in September 2020 to encourage people to meditate for free.

Insight Timer

<div>
 
 Big Sky Health is the developer of the Oak Meditation breathing app. Oak Meditation offers guided and unguided meditations, sleep meditations, meditation timers, yogic exercises for breathing, animated instructions, and music tracks. The company is headed by Mike Maser, an entrepreneur who was diagnosed with stage IV cancer. Most of the companies services are offered free of charge with in-app purchases ranging from USD 5.99 to USD 38.99.
 
 
 
 
 In addition to Oak meditation, Big Sky also offers a fasting app called Zero and an alcohol moderation app called Less. In May 2020, Big Sky raised USD 8 million in Series A funding in a round led by Greycroft with participation from existing investors True Ventures and Trinity Ventures, bringing the company’s total funding to USD 12.2 million. Big Sky Health expects to use the funds to expand its staff and boost customer acquisition.
 
</div>

Big Sky Health

Apps that provide relaxation, stress reduction and non-therapeutic mental health support via meditation-related techniques.

These apps aim to increase users’ body and brain functions including memory and attention to detail with microlearning, gamification, and journaling techniques.

Helps users analyze and address sleep disorders with wearable tech, music and sound therapy, and storytelling.

Apps that provide virtual training programs, track workouts, and provide guides for nutrition.

Companies that use GenAI as a core part of their product offering for Digital Wellness

Some digital wellness providers provider VR/AR experiences for meditations

Some companies offer personalized care/meditation plans, workout regimens, or treatments for sleep disorders

Offers app-based platforms that improve health and wellness

Wellness providers use GenAI to enhance their solutions

<div>
 
 California-based Tripp is a digital psychedelic startup that provides wellness solutions in the form of guided meditations and personally curated mindfulness exercises, to improve focus, concentration and enhance mental wellness.&nbsp;
 
 
 The company offers a meditation and mindfulness app that uses VR &amp; AR to deliver psychedelic visual and audio experiences, similar to what people experience during a psychedelic trip, without the use of psychedelic drugs. In August 2021, the company entered the psychedelic clinics business through the acquisition of PsyAssist, a digital startup that provides support for at-home prescribed psychedelic-assisted therapies, to launch a new product called the &ldquo;TRIPP PsyAssist&rdquo; which will provide step-by-step guidelines to psychotherapists and patients for before, during, and after psychedelic-assisted therapies. The company&rsquo;s focus is on ketamine-based therapies, however, it plans to support psilocybin and 3,4-Methylenedioxymethamphetamine (MDMA) clinical trials in future.&nbsp;
 
 
 Tripp caters directly to consumers and also through employer benefit plans. It is also researching other non-chemical, digital methods to tackle mental health issues and is participating in several clinical trials to understand the effectiveness of the Tripp platform as a therapeutic device to treat anxiety, depression, and substance use disorders.&nbsp;
 
 
 Key Customers and Partnerships
 
 
 In January 2023, the company partnered with fellow mindfulness provider, 
 <a href="https://sp-edge.com/updates/15998">
 Equa Health
 </a>
 , to develop clinically validated mindfulness training modules covering concentration power, equanimity (or calmness), and sensory clarity, known as &ldquo;experiences.&rdquo; The companies plan to offer introductory series on TRIPP&rsquo;s platform, from which feedback will be gathered to expand the series further.&nbsp;
 
 
 Funding and Financials
 
 
 Founded in 2017, Tripp has delivered more than 2 million TRIPP sessions to date. In June 2021, the company raised USD 11 million in a Series A funding round and intends to use the proceeds for upscaling business operations via advancing research and development (R&amp;D), growing the team, and expanding its user base. The last funding round brings the company&rsquo;s total funds raised up to USD 15 million.
 
</div>

<div>
 
 Canadian biotech firm Core One Labs maintains three primary business operations: 1) developing novel delivery systems for psychedelic medicines, 2) psilocybin manufacturing, and 3) medical clinics to provide psychedelic-assisted psychotherapy. The company has developed proprietary technology with infused strips that dissolve immediately when placed in the patient&rsquo;s mouth to deliver molecules with a higher level of bioavailability. The company plans to advance this technology to incorporate psychedelic molecules, particularly psilocybin.&nbsp;
 
 
 Core One Labs also claims it has discovered a patentable method of producing high-quality psilocybin, which it may license to pharmaceutical companies. Additionally, the company has two psychedelic clinics in Vancouver that currently support clinical trials and maintain a database of more than 275,000 patients. The company acquired Vocan Biotechnologies and Akome Biotech in May 2021 for undisclosed amounts. Akome is developing a patent-pending psychedelic drug formulation for the treatment of Alzheimer&rsquo;s Disease.&nbsp;
 
 
 Core One Labs is listed on the Canadian Securities Exchange (CSE) and OTC markets.
 
 
</div>

Core One Labs

<div>
 
 Vancouver-based Lobe Sciences (formerly GreenStar Biosciences) is a biotechnology company developing psychedelic medicines (microdose applications) and medical devices for efficient drug delivery. The company&rsquo;s main focus is the treatment of mild traumatic brain injury and post-traumatic stress disorder (PTSD). It is also conducting early studies on psilocybin combined with N-acetylcysteine (NAC), and MDMA combined with NAC as a treatment. Lobe is also developing a patent pending nasal mist transducer device for the delivery of medicines directly to the brain&rsquo;s olfactory bulb.&nbsp;
 
 
 In June 2020, Lobe acquired Eleusian Biosciences, a company focused on the development of psychedelic medicine which expanded its intellectual property portfolio with three US patent applications for psychedelic therapeutics. Lobe is also collaborating with the University of Miami&rsquo;s Miller School of Medicine to conduct preclinical studies. After its restructuring and name change, the company started trading on the Canadian Securities Exchange (CSE) in November 2020.
 
 
 
</div>

Lobe Sciences

<div>
 
 Cybin is a psychedelic biotechnology company developing treatments for psychiatric and neurological conditions. Through its Serenity Life Science division, Cybin conducted Phase II of clinical trials on using psilocybin to treat major depressive disorder. Additionally, the company's Nature's Journey division focuses on creating non-psychedelic medicinal and nutraceutical mental health products.
 
 
 Cybin is actively building a patent portfolio, including chemically-synthesized compounds, delivery mechanisms, protocols, and new drug formulations. It has also filed an International Patent Application through the Patent Cooperation Treaty, potentially covering 153 countries.&nbsp;
 
 
 In July 2023, the company announced 
 <a href="https://sp-edge.com/updates/20076">
 EMBARKCT, 
 </a>
 a streamlined version of its EMBARK training program for pivotal studies of lead candidates, CYB003 for major depressive disorder and CYB004 for generalized anxiety disorder, respectively. In 
 <a href="https://sp-edge.com/updates/27577">
 March 2024
 </a>
 , the company received a breakthrough designation from the FDA for CYB003, and expects to initiate Phase III clinical trials for the program by mid-2024.
 
 
 Cybin implements an M&amp;A strategy to grow in the psychedelic industry. It did a reverse takeover of Charmin in June 2020, raising CAD 45 million (USD 35.5 million) for clinical studies. It acquired Adelia Therapeutics in December 2020, adding novel treatments and patent applications. Also in 
 <a href="https://sp-edge.com/updates/21335">
 August 2023 
 </a>
 it acquired 
 <a href="https://sp-edge.com/companies/470858">
 Small Pharma 
 </a>
 in an all-share transaction to strengthen its psychedelic portfolio.&nbsp;
 
 
 Founded in 2019, Cybin is listed on the NEO exchange under the ticker symbol &ldquo;CYBN&rdquo; and was uplisted to the NYSE American Stock Exchange in July 2021 under the same symbol. For FY2023, the company reported a decrease in net loss by 29.7% YoY to CAD 47.5 million (USD 35 million).&nbsp;
 Further in 
 <a href="https://sp-edge.com/updates/33849">
 September 2024
 </a>
 , it completed a 38-to-1 share consolidation of its common stock which reduced the number of outstanding common shares to ~20 million. 
 
 
 Key customers and partnerships&nbsp;
 
 
 In July 2020, Cybin expanded its operations and research activities in the European region via research partnerships and transferred its intellectual property assets to its fully-owned Irish subsidiary (formed in May 2021). In July 2023, the company partnered with 
 <a href="https://sp-edge.com/updates/20455">
 Worldwide Clinical Trials
 </a>
 to develop new psychedelic-based treatment options for mental health conditions, including major depressive disorder. Further, in September 2023, the company partnered with 
 <a href="https://sp-edge.com/updates/22180">
 Fluence
 </a>
 to support Cybin's EMBARK facilitator training program.
 
</div>

Cybin

<div>
 
 Canadian cannabinoid-based therapeutics company BioNxt Solutions
 (formerly Xphyto Therapeutics) announced in November 2020 that it has expanded its drug development program to incorporate a number of psychedelic compounds. This includes substances such as psilocybin, mescaline, LSD, MDMA, and DMT. Xphyto&rsquo;s initial focus is on developing standardized drug formulations with efficient delivery mechanisms for therapeutic use.
 
</div>

BioNxt Solutions

<div>
 
 New York-based Gilgamesh Pharmaceuticals is a biotechnology company developing psychedelic-inspired medicines for neuropsychiatric conditions such as depression, anxiety, addiction, and cognitive deficits. The company has three research programs in its pipeline: 1) Serotonergic Micro-Dose&ndash;a non psychedelic therapeutic treatment for attention deficit hyperactivity disorder (ADHD) and mood/anxiety disorders, 2) Arylcyclohexylamine&ndash;an improved molecule of ketamine for treatment-resistant depression and opiate use disorder, and 3) Novel Ibogaine Analogue&ndash;for the treatment of substance use disorders.&nbsp;
 
 
 Gilgamesh is one of the few psychedelic companies launched by the startup accelerator Y Combinator, and as such enjoys the accelerator&rsquo;s world-famous business expertise and network.
 
 
 Key customers and partnerships
 
 
 In 
 <a href="https://sp-edge.com/updates/29382">
 May 2024
 </a>
 , the company partnered with AbbVie to leverage AbbVie's psychiatric expertise and Gilgamesh's research platform to create novel &quot;neuroplastogens.&quot; 
 
 
 Funding and Financials
 
 
 In 
 <a href="https://sp-edge.com/updates/27575">
 March 2024
 </a>
 , the company received a grant of&nbsp; USD 14 million from the National Institute on Drug Abuse to develop the GM-3009 compound. Prior to this, it raised USD 39 million in a 
 <a href="https://sp-edge.com/updates/15359">
 Series B 
 </a>
 funding round led by Prime Movers Lab in December 2022. 
 
</div>

Gilgamesh Pharmaceuticals

Companies conducting research on psychedelic compounds and developing novel therapeutics.

Companies operating digital platforms to deliver psychedelic therapies including psychedelic integration, virtual experiences, and mental coaching and tracking. AI drug discovery companies specializing in psychedelic therapeutics are also included.

Companies operating clinics and treatment centers to deliver psychedelic therapies.

Companies supplying psychedelic compounds through cultivation, chemical synthesis and biosynthesis for medical research and drug development.

Companies building a patent portfolio of novel analogs and derivatives of first-generation psychedelics and new drug delivery mechanisms. 

ANALYST_QUICK_TAKE

PROMINENT_CATEGORY

<div>
 The digital wellness firm Tripp has introduced a beta version of Kōkua XR, an AI-powered meditation guide for tailored wellness experiences. The application is accessible for Quest headsets and comes with a monthly subscription fee of USD 9.99.
 Kōkua XR offers personalized meditation sessions influenced by real-time user input. Users are able to verbalize and let the application use a large language model (LLM) for guidance during meditation. Additional features include mood monitoring using heart rate and breathing pattern data.
</div> Analyst QuickTake: 
 The news follows Headspace’s entry into the XR sector via the launch of its VR meditation app in <a href="https: 
//sp-edge.com/updates/27329"> March 2024 </a> . Kōkua XR differentiates itself via its subscription pricing (Headspace XR is available for a flat fee of USD 20). While Tripp’s Kōkua XR is potentially more expensive than Headspace XR in the long run, this premium is likely due to the incorporation of its suite of AI features.

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