Khosla Ventures invests in companies that are bold, early, and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs. Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech, digital health, medtech and diagnostics, therapeutics, and frontier technology.

Khosla Ventures

StartX is a 501(c)(3) Stanford-affiliated nonprofit in Silicon Valley that runs one of the world’s top startup accelerator programs. Its mission is to advance the development of the best entrepreneurs through experiential education and peer learning. Since launching in 2010, it has supported more than 450 companies and 1000 entrepreneurs, from early to pre-IPO stage, working across a wide spectrum of industries.    StartX and StartX Med, dedicated to medical and biotechnology innovation, provide founders with access to a powerful network of entrepreneurs, investors, mentors, and industry partners, along with office space and a variety of other resources. Based in Palo Alto, the accelerator also operates StartX-QB3 Labs and the Stanford-StartX Fund. We are funded by Stanford University, Stanford Health Care, Microsoft, Steelcase, Hyundai, Oriza Ventures, Nissan, Panasonic, Lightspeed Venture Partners, Analog Devices, Silicon Valley Bank, Greylock Partners, Sequoia Capital, and many others. For more information, visit startx.com The company is associated investment vehicle, the Stanford-StartX Fund is a partnership between StartX, Stanford University and Stanford Health Care.  It can invest only in StartX companies who raise qualified rounds of venture capital using objective criteria; it is founder opt-in.

StartX (Stanford-StartX Fund)

Northpond Ventures is a science-driven venture capital ﬁrm headquartered in Bethesda, Maryland. Our mission is to build a better tomorrow.  Our investments are focused on life sciences, technology, and aﬃliated industries.

Northpond Ventures

Think.Health invests as a boutique risk-taker in healthcare ventures. We continuously seek innovations and disruptive business models in digital healthcare, medical technologies and health service providers,

Think.Health

Grey Sky Venture Partners is a new early-stage investment firm that invests in the areas of healthcare sectors.

Grey Sky Venture Partners

D1 Capital Partners is an investment firm that deploys capital in both public and private markets. It invests on behalf of investors globally, including endowments and foundations, family offices, sovereign wealth funds, outsourced CIOs, hospitals, and pensions. D1 has a fundamental and research-intensive investment strategy with a focus on medium to long-term returns. Its research centers on the consumer, business services, financial services, healthcare, industrials, real estate and technology, media, and telecom sectors.

D1 Capital Partners

OSF Ventures invests financially and operationally in opportunities that will improve patient outcomes, enhance patient experience and reduce the cost of health care. They believe in not only investing financially, but also strategically through comprehensive collaboration.  OSF Ventures employs the principles of humble curiosity and considered risk to create conditions conducive to exploring new thinking, challenging conventions and championing better, more compassionate care for all.  OSF Ventures is a member of the OSF HealthCare family, located in Illinois and Michigan. OSF HealthCare was founded to continue the healing Ministry of Jesus Christ. ''Embracing God’s great gift of life, we are one OSF Ministry transforming health care to improve the lives of those we serve.''

OSF Ventures

Leblon Capital

Vesalius Biocapital Partners invests in companies active in human health through venture capital funds raised since 2007. They have contributed to developing 20 companies since inception. With more than € 150 million under management in two funds. Vesalius Biocapital Partners plays the role of lead investor in the large majority of its financing rounds.   Their companies are based in Europe allowing easy interaction with management. They invest in all stages of development and do not shy away from relatively early-stage projects with a sound proprietary technology and corresponding IP, unique team skills and a clear competitive edge based on solid data.

Vesalius Biocapital Partners

OSF HealthCare is an integrated health care network serving the patients and families of central and northern Illinois and northern Michigan.  OSF HealthCare, owned and operated by The Sisters of the Third Order of St. Francis, Peoria, Illinois, includes OSF Healthcare System consisting of eight acute care facilities and two colleges of nursing. It also has a primary care physician network consisting of over 600 primary care, specialist physicians, and advanced practice providers.   OSF HealthCare owns OSF Saint Francis, Inc., comprised of health care-related businesses, and OSF Healthcare Foundation, the philanthropic arm of OSF Healthcare System and OSF Home Care Services.  OSF HealthCare is a multi-state corporation, operating facilities in Illinois and Michigan, providing state-of-the-art, compassionate care to more than 2.5 million people in the communities they serve.

OSF Healthcare System

Iberis is an investment manager that operates a value-oriented investment management.

Iberis Capital

Raw Ventures is an investment firm that mainly focuses on making pre-seed through to mid-stage investments in companies.

Raw Ventures

Inflammatix

Inflammatix develops novel molecular diagnostics for acute infections and sepsis that work by 'reading' the immune system.  It is a molecular diagnostics company developing rapid tests that read the immune system to resolve major clinical and public health challenges. They are initially focused on developing tests for acute bacterial and viral infections, and sepsis based on patent-pending biomarkers exclusively licensed from Stanford University.

Inflammatix is developing novel diagnostics that rapidly interpret the body's immune response to aid in diagnosing patients with suspected acute infections and sepsis. Its lead product, the TriVerity Acute Infection and Sepsis Test System, comprises the Myrna Instrument and the TriVerity Test.

Pushing the envelope in MedTech with emerging technologies

Next-gen Medical Devices

Inflammatix Initiates TriVerity™ for Improved Management of Emergency Department Patients with Suspected Infections (TIMED) Trial

Inflammatix is developing novel diagnostics that rapidly interpret the body's immune response to aid in diagnosing patients with suspected acute infections and sepsis. Its lead product, the TriVerity Acute Infection and Sepsis Test System, comprises the Myrna Instrument and the TriVerity Test.The TriVerity Test incorporates a panel of 29 messenger RNAs (mRNAs) to "read" the immune response, providing three independent readouts: The likelihood of a bacterial infection, viral infection, and risk of severe illness requiring ICU-level care within seven days. It is designed for emergency departments to facilitate the diagnosis and prognosis of patients with suspected acute infections, an area where physicians often struggle. The Myrna Instrument enables sample-to-answer quantitation of up to 64 mRNAs from whole blood in about 30 minutes.&nbsp;In November 2023, the FDA granted breakthrough device designation to the TriVerity Test System, reflecting its potential to improve the standard of care and placing it on an accelerated pathway to clearance. This designation also makes TriVerity eligible for Medicare reimbursement benefits to expedite hospital implementation.Key customers and partnershipsAs of August 2024, Inflammatix’s technology was being developed for the healthcare sector, primarily focusing on emergency medical services.In September 2023, Inflammatix partnered with Acutelines to develop a smart tool aimed at the early detection of sepsis and providing clinical decision support.

Convergent Dental, Inc. is a privately owned dental equipment and technology company. Its flagship product, Solea, is the only CO2 laser cleared by the FDA for all-tissue indications, delivering an anesthesia-free, blood-free, and suture-free experience for dentists and patients. Solea represents a breakthrough in dental laser technology, offering a distinct experience compared to traditional instruments or earlier laser treatments.
Solea is a novel 9.3-micron CO2 laser that nears the peak absorption of hydroxyapatite (enamel), enabling it to vaporize enamel with speed and precision. This unique wavelength, coupled with computer-controlled motors (galvos) that manipulate the beam thousands of times per second, allows dentists to perform procedures ranging from hard tissue to soft tissue with total control and efficiency.
A key feature of Solea is its variable-speed foot pedal, which lets dentists seamlessly transition from hard to soft tissue by adjusting the pressure applied. This intuitive design streamlines the learning curve for dentists accustomed to using a drill. Solea's three ergonomic handpieces – Contra-Angle, Straight, and Ultraguide – further enhance its versatility across various procedures.
Solea not only improves patient experiences but also offers practice benefits such as increased productivity, new patient flow, and efficiency gains. In October 2022, Convergent Dental received FDA clearance for Solea to aid in reducing mineral loss in dental enamel, protecting teeth against acid attack and caries development. This breakthrough application was commercially launched in November 2023 under the name Solea Protect.

Convergent Dental

Ossio is an orthopedic fixation technology company that has developed OSSIOfiber Intelligent Bone Regeneration Technology, a breakthrough implant material designed to securely fixate and fully integrate into the body's native anatomy without leaving any permanent hardware behind. This technology addresses the limitations of conventional metal and resorbable implants, combining unparalleled mechanical strength with natural bone healing.
Made from a proprietary mineral fiber matrix held together by a naturally degradable polymer, OSSIOfiber implants provide surgeons with a more biologically friendly way to restore patient stability and mobility. These implants are engineered to provide the strength required for functional fixation while allowing full integration into the native bone without adverse biological response.
Ossio's product portfolio includes compression screws, trimmable fixation nails, hammertoe fixation systems, suture anchors, and compression staples, all made with OSSIOfiber technology. These implants have received multiple FDA clearances since 2019, and the company has initiated commercialization of its products in the US. As of March 2022, over 6,000 implantations of OSSIOfiber products had been performed, demonstrating adoption of this innovative technology.
OSSIOfiber Intelligent Bone Regeneration Technology can address various surgical applications through the manufacturing of implant designs like nails, screws, staples, anchors, and plates. Ossio plans to pursue multiple applications in distal extremities, trauma, sports, reconstruction, pediatrics, and spine segments.
In February 2023, Ossio launched the world's first and only non-permanent compression staple made with OSSIOfiber technology, designed for predictable bone in-growth, regeneration, and replacement.

Ossio

Casana is a healthcare technology company that has developed the Heart Seat, an innovative toilet seat that enables effortless, integrated, and consistent in-home health monitoring. The Heart Seat is a replacement for a standard toilet seat and is designed to measure key clinical parameters such as heart rate, blood oxygen saturation (SpO2), and blood pressure.
In May 2023, Casana received FDA clearance for the Heart Seat to measure heart rate and SpO2 in adults aged 22 years and older, weighing between 90 to 350 pounds. The company plans to file for additional indications, including systolic and diastolic blood pressure, with the goal of launching the product in the market by the end of 2023.
The Heart Seat is equipped with sensors that passively capture health data whenever the seat is used, eliminating the need for user compliance or behavior changes. The data is automatically uploaded to the Casana Cloud, where it can be viewed by healthcare providers, enabling them to monitor patients' health trends and respond to changes in near real-time.
Casana's technology allows for the effortless collection of consistent and reliable data, assisting medical teams in monitoring chronic conditions beyond the hospital or physician's office. The company aims to unlock a new category in healthcare technologies that enables seamless, integrated, and continuous in-home health monitoring.
In January 2022, Casana was acquired by an undisclosed entity, further accelerating the commercialization of the Heart Seat.

Casana

Neurent Medical is a company pioneering innovative non-surgical interventions to treat chronic inflammatory sinonasal diseases, particularly chronic rhinitis. The company's flagship product is the NEUROMARK System, a device that received US Food and Drug Administration (FDA) 510(k) clearance in October 2021.
The NEUROMARK System is designed to gently apply controlled low-power radio frequency (RF) energy to target regions of the nasal cavity, disrupting the parasympathetic nerve signals that can trigger an inflammatory response. This alleviates chronic rhinitis symptoms such as persistent congestion, rhinorrhea (runny nose), swelling of the mucosal membrane, sneezing, and nasal itching. The system's unique flexible leaflet design and proprietary smart algorithms enable precise neurolysis (disruption) of the posterior nasal nerves (PNN) and accessory pathways, accommodating a range of patient anatomies while maintaining mucosal and vascular integrity.
Neurent Medical announced the limited market release of the NEUROMARK System in the US in February 2023, following the establishment of a new Category I Current Procedural Terminology (CPT) code by the American Medical Association (AMA) for PNN procedures, effective January 2024. The American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) also endorsed the PNN procedure in 2023.

Neurent Medical

Genetesis is a medical imaging company specializing in biomagnetic cardiac imaging solutions. It has developed CardioFlux, a flagship magnetocardiography (MCG) system that non-invasively identifies myocardial ischemia, a condition where blood flow to the heart muscle is reduced. The technology measures the magnetic fields generated by the heart's electrical activity to detect ischemia within minutes, without using pharmaceuticals or radiation. CardioFlux MCG is designed to provide advanced imaging while prioritizing patient comfort.
The company's solutions target the diagnosis of coronary microvascular disease (CMD), a condition that has been challenging to identify due to a lack of effective functional diagnostics. By offering an accurate and rapid test for CMD, Genetesis aims to address an unmet clinical need and enable timely management of the condition.
In April 2023, the US Food and Drug Administration (FDA) granted CardioFlux MCG Breakthrough Device designation for the non-invasive diagnosis of myocardial ischemia in patients suspected of having CMD.
Genetesis was founded in 2013 and is headquartered in Mason, Ohio. The company has received over USD 40 million in funding to date, including a USD 17.5 million Series C round in October 2022. In April 2020, TDK Ventures, the corporate venture capital arm of TDK Corporation, invested in Genetesis, providing access to TDK's expertise in areas like biomagnetic sensors and magnetic noise suppression.

Genetesis

Companies that develop diagnostic devices used in a hospital setting to identify a disease, condition, or injury, such as imaging systems and endoscopes

Companies that develop implantable medical devices designed to be surgically placed inside the human body, either temporarily or permanently, including devices such as pacemakers, artificial joints, stents, and cochlear implants

Companies that develop non-surgical devices that are used in a procedure or intervention to cure or relieve a patient from an illness or disease such as laser treatments, dental equipment, and wound care management

Companies that develop monitoring devices that are used in a hospital setting to measure patient vital signs and ensure patient well-being post-treatment, such as cardiac and respiratory monitoring systems

Providers of software that enhances the functionality of medical device hardware (diagnosis, treatment, and monitoring)

Companies that develop surgical devices involving invasive interventions (cutting into a patient's body tissues) to treat, cure, or relieve a patient of an illness or disease

Companies that develop devices to administer pharmaceutical substances into a patient's body, ensuring controlled release or targeted delivery, specifically for use in clinical settings to treat or manage medical conditions effectively

Providers of software that helps manage risks, ensure quality, and streamline audit processes during medical device development

IoT connects devices to EHR systems for precise patient diagnosis and treatment support

Devices are linked to software platforms that use digital technologies such as AI/ML and VR

Startups leverage AI/ML and deep learning to support patient diagnosis and early detection

<div>
 
 Inflammatix, a company specializing in molecular diagnostics, has successfully raised USD 57 million in their Series E funding round. The round was led by Khosla Ventures and Think.Health, with contributions from D1 Capital Partners, Iberis Capital, OSF Healthcare, RAW Ventures among others. 
 The funds will go into facilitating regulatory filing and the early stages of the commercialization process for the company's top product, the TriVerity Acute Infection and Sepsis Test. As Inflammatix eagerly awaits FDA clearance, anticipated to be granted later this year, this test is instrumental in measuring gene expression levels in blood associated with immune reactions. The results of the test are typically delivered in around 30 minutes.
 
</div>

Inflammatix

About EDGE

Contact Us

Resources

Area of Focus

Technology Research Made Effortless