First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies, including Uber, Square, and Warby Parker. Through custom-built software, incredible in-person experiences, and a host of other unique services, First Round helps tiny companies get big while constantly reimagining the role of venture capital. It offers a growing number of services and products to help founders build companies from scratch. First Round has adopted the Diversity Term Sheet Rider.

First Round Capital

Threshold is an early-stage venture capital firm that focuses on a high-conviction investment strategy. The firm partners with entrepreneurs to build innovative consumer, enterprise, and healthcare technology companies.

Threshold

SV Angel is a service organization, investing in founders who share these values. They support entrepreneurs in building lasting companies by assisting at key inflection points and leveraging networks to help them propel their businesses forward.

SV Angel

Quaker Partners is a healthcare investment firm focused on companies based on the U.S. East Coast.

Quaker Partners

Refactor is a seed-stage VC firm investing in bio, climate, and hard tech startups run by Zal Bilimoria. Zal was a partner at a16z and PM for a decade at Google, Netflix, and LinkedIn. He led the seed rounds of Solugen, Astranis, and many other hard tech startups. He is the only decision maker at the firm, writing $1-2M checks in pre-seed and seed rounds.

Refactor

Venture capital fund focused on early healthcare opportunities in the US.

Meridian Street Capital

Bragiel Brothers is an early-stage venture capital fund that invests in seed and Series A rounds.   Dan Bragiel launched the firm in San Francisco, California in 2016.

Bragiel Brothers

Transformation Capital is the successor management company to Leerink Transformation Partners LLC (“LTP”).11  LTP was founded in 2016 by Todd Cozzens and Jared Kesselheim, MD together with SVB Leerink Capital LLC (formerly Leerink Capital Partners LLC) (“Leerink Capital”), an affiliate of SVB Leerink LLC (“Leerink”), a leading healthcare investment bank.  Leerink Capital provided seed capital to Fund I (approximately 3% of capital commitments) and operational support. In January 2019, SVB Financial Group (“SVB”), the holding company of Silicon Valley Bank, a U.S.-based high-tech commercial bank, acquired the Leerink businesses including Leerink Capital.  Todd Cozzens, Jared Kesselheim, MD, and SVB expect to agree to a mutually beneficial ongoing relationship in which Transformation Capital (as an independent management company owned by Todd Cozzens, Jared Kesselheim, MD, and Michael Dixon and not affiliated with SVB or Leerink Capital) shall manage Fund II and whereby Transformation Capital shall manage Fund I’s investment portfolio pursuant to a sub-advisory agreement with SVB (or an affiliate).  Transformation Capital has the same operational leader, Kevin Brown, formerly CFO of Leerink Capital, and Transformation Capital expects to continue to derive benefits from its ongoing relationship with Leerink and SVB.

Transformation Capital

Vital

Keep patients more informed and engaged in the emergency room, hospital, and beyond. Vital’s AI-powered patient experience solutions give patients control, clarity, and predictability when they need it most.

Vital is a healthcare technology company that develops artificial intelligence (AI)-driven software solutions aimed at improving the patient experience within and beyond the hospital setting. Their core offerings include ERAdvisor and CareAdvisor, intuitive and user-friendly platforms designed to streamline communication and engagement between healthcare providers and patients during emergency department (ED) visits and inpatient stays.

VitalCare

Vital Care Industries – Quality Surgical Supplies

Matchstiq

Vital Surpasses 1,000,000 Users with AI-Powered Care Experience Technology

Vital Health LLC

Simplifying healthcare administration with intuitive tech tools

Hospital Management

Vital Says Targeting Incremental Improvement To Underlying Financial Performance In FY25

Vital is a healthcare technology company that develops artificial intelligence (AI)-driven software solutions aimed at improving the patient experience within and beyond the hospital setting. Their core offerings include ERAdvisor and CareAdvisor, intuitive and user-friendly platforms designed to streamline communication and engagement between healthcare providers and patients during emergency department (ED) visits and inpatient stays.
Vital's technology leverages cutting-edge AI and natural language processing (NLP) capabilities to transform complex healthcare data into simple, consumer-friendly digital experiences. This approach allows patients to better understand their care journey, set expectations, complete tasks, request services, receive status updates, share progress with loved ones, and provide feedback, all through a seamless and accessible interface accessible via their mobile devices.
One of Vital's key differentiators is its exceptional user adoption rate. As of July 2023, over 57% of patients who arrive at a Vital customer's emergency department utilize the ERAdvisor solution, a rate five times higher than competing solutions. This statistic underscores the company's commitment to delivering intuitive and user-centric experiences that resonate with patients.
As of July 2023, Vital's solutions were being utilized by over 100 hospitals across 28 different health systems spanning 19 states in the US, a testament to the company's rapid growth and market penetration. In the same year, Vital reached a significant milestone by surpassing one million users of its innovative technology solutions.

Modernizing Medicine is a healthcare technology company that specializes in developing cloud-based electronic health record (EHR) systems and solutions tailored for specific medical specialties. Their flagship products, EMA and gGastro EHR, are designed to streamline clinical workflows and documentation processes, saving time for healthcare providers. These intuitive platforms incorporate built-in medical knowledge and can adapt to individual practice preferences.
Beyond EHRs, Modernizing Medicine offers an integrated suite of products and services, including practice management, revenue cycle management, endoscopy report writing, analytics, and advisory services. Their solutions aim to address the challenges of value-based care, such as population health management, quality measure reporting, and optimizing reimbursements.
Modernizing Medicine's innovative EHR architecture emphasizes speed, convenience, and adaptability, enabling doctors to complete exams efficiently. The systems can generate notes, suggest codes, and automate billing processes, reducing administrative burdens.
In November 2022, Modernizing Medicine agreed to pay USD 45 million to resolve allegations of accepting and paying illegal kickbacks, as well as causing users to report inaccurate information for federal incentive payments. The settlement addressed three marketing programs alleged to have violated the False Claims Act and the Anti-Kickback Statute.

Modernizing Medicine

Kyruus Health is a leading provider of care access solutions that connect patients with the right healthcare providers. The company's platform integrates comprehensive provider data, enabling informed decisions and seamless access to care across various touchpoints. Kyruus Health's offerings include provider search and scheduling tools, cost transparency solutions, and data management capabilities.
Kyruus Health's technology facilitates provider matching, appointment scheduling, and digital patient intake processes. The platform enhances the overall patient experience by streamlining access to care and ensuring transparency regarding provider expertise, availability, and costs. Additionally, Kyruus Health's solutions empower healthcare organizations, such as hospitals, medical groups, and health plans, to optimize provider utilization and comply with industry mandates.
Through strategic acquisitions and partnerships, Kyruus Health has expanded its network to encompass over 425,000 providers across more than 1,000 hospitals and 500 medical groups. As of 2023, the company served over 90 million health plan members from 100 different health plan brands, solidifying its position as a leading care access platform.
Key customers and partnerships
In July 2024, Kyruus Health announced a strategic partnership with XO Health, an innovative healthcare services organization designed for self-insured employers. This collaboration aimed to enhance XO Health's digital member experience by integrating Kyruus Health's provider search and cost transparency tools, ultimately creating a seamless healthcare journey for members, providers, and payers.
Furthermore, in May 2024, Kyruus Health expanded its national provider network by integrating virtual behavioral health providers, demonstrating its commitment to improving access to mental health services. This expansion added over 30,000 virtual behavioral health providers to the Kyruus Network, enabling health plans, hospitals, and medical groups to seamlessly integrate these providers into their online directories and address access gaps.
Kyruus Health also partnered with WellHive and V3 Gate to support the Veterans Health Administration (VHA), aiming to improve care for all Veterans by accelerating access to care through centralized appointment management across VHA sites.

Kyruus

AKASA is a healthcare technology company that leverages advanced generative AI and machine learning models to address administrative inefficiencies and financial challenges in the revenue cycle management (RCM) process. Their AI solutions are specifically trained on vast amounts of clinical and financial data to comprehend the nuances of the healthcare industry.
AKASA's platform is powered by large language models and generative AI capabilities akin to ChatGPT, but optimized and tailored for the healthcare domain. Their AI understands clinical context, grasps the intricate details of health systems, and is designed to integrate directly into staff workflows, enabling automation of routine tasks and improving operational efficiencies.
The company takes an "expert-in-the-loop" approach called Unified Automation, which combines machine learning with human expertise. This allows their technology to adapt to the dynamic nature of revenue cycle operations while benefiting from the judgement of AKASA's in-house team of RCM veterans with an average of over 15 years of industry experience.
AKASA's solutions aim to reduce the substantial administrative waste associated with billing and insurance communication failures, estimated at over USD 500 billion annually in the USD 4 trillion healthcare industry. By automating comprehensive and complex tasks, AKASA enables healthcare providers to reallocate staff toward patient-facing activities and enhance care delivery.

AKASA

XSOLIS is an AI technology company that offers a platform and solutions to create a more efficient healthcare system by facilitating improved communication and alignment between healthcare providers and payers. The company's flagship product, CORTEX, is an AI-driven platform that utilizes real-time predictive analytics to continuously assign an objective medical necessity score and assess the anticipated level of care for every patient. This technology aims to eliminate waste by leveraging data science, automation, transparency, and objective insights to ensure appropriate care settings.
XSOLIS's solutions streamline patient status communications, enabling providers and payers to align on medical necessity, length of stay timelines, and appropriate care levels. The platform's AI capabilities enable the creation of live clinical profiles for each patient, recognizing patterns to generate predictive analytics for determining the most suitable care setting. CORTEX reduces the administrative burden of case reviews through its proprietary Care Level Score (CLS), allowing teams to prioritize discharge planning tasks and driving optimal workflows.
By August 2022, XSOLIS achieved a three-year revenue growth of 388%, ranking No. 1795 on the 2022 Inc. 5000 list of America's fastest-growing private companies. The company reported 111% growth in its payer network and a 44% increase in hospital partnerships in the same year.

XSOLIS

Suki AI is a healthcare technology company that develops an AI-powered voice assistant, Suki Assistant, designed to help clinicians complete administrative tasks efficiently. The Suki Assistant utilizes natural language processing and generative AI to transcribe conversations between clinicians and patients into clinical notes, populating electronic health records (EHRs) with relevant data. By automating documentation, the company aims to reduce the time clinicians spend on paperwork, claiming to shrink it by as much as 72% in family medicine settings.
Suki Assistant offers multiple modes, including ambient note generation, dictation, and voice commands. The ambient mode leverages generative AI to listen to clinician-patient interactions and auto-generate clinical notes in real-time without human intervention. Clinicians can accept, reject, or edit the AI-generated content to ensure accuracy. In addition to documentation, Suki Assistant can retrieve patient information, such as medication lists and allergies, from EHRs and provide diagnosis code recommendations.
Suki Assistant is deeply integrated with major EHR systems, including Epic, Cerner, athenahealth, Elation, and Meditech, enabling bidirectional synchronization of notes and codes. The company expanded its capabilities to support inpatient care settings in October 2023, making it the first AI-powered voice solution tailored for clinicians in hospitals. Suki Assistant operates across various platforms, including iOS, Android, web, Windows, Mac, and as a Chrome extension.
In October 2023, Suki announced the acquisition of an undisclosed company to enhance its personalization features, allowing the assistant to adapt to individual user preferences and existing workflows.

Suki

Platforms used by hospitals to manage the various aspects of patient care to improve overall efficiency, such as automating routine tasks, improving communication and coordination among healthcare providers, and enhancing patient outcomes within the hospital setting

Platforms that enable patients to actively participate in their healthcare journey by educating and engaging them, along with improving communication with healthcare providers

Platforms that help healthcare organizations analyze patient data and other performance metrics to improve decision-making and optimize resource allocation

Platforms that are designed to help hospitals and health systems manage their financial operations from patient billing and insurance claims to revenue tracking and analysis

AI-powered software solutions that are designed to help healthcare organizations streamline and automate the process of documenting patient encounters

Companies that use GenAI as a core part of their product offering for hospital management

Offers software platforms that streamline and improve hospital operations

AI/ML algorithms optimize workflows, enable predictive modeling, and analyze patient data in healthcare

Hospital Management companies use GenAI to manage and automate administrative tasks, offering a range of tech solutions designed to meet the needs of different departments and functions.

IoT medical solutions turn traditional hospitals into smart hospitals, allowing them to streamline workflows

Vital

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