The Pritzker Organization is a private investment firm that funds, acquires, and builds companies.TPO is focused on partnering with exceptional leaders to create value across a wide range of industries. TPO looks for opportunities where it can create value for the family's interests and those of its partners and colleagues over a significant time horizon. For more than 60 years, TPO has overseen and guided the development of dozens of portfolio companies across a wide variety of industries, including manufacturing, logistics, life sciences, hospitality, healthcare, and services.

The Pritzker Organization

Segulah Medical Acceleration is a Scandinavia-based investment company focusing on innovative medical technology companies in Europe.

Segulah Medical Acceleration

Pioneer Healthcare Partners, LP (“PHP”) is the private equity arm of Pioneer Group Holdings, LLC (“Pioneer”) the investment office for the Parkinson Family. Pioneer was founded in 2018, by Robert L. Parkinson Jr., the former Chairman and CEO of Baxter International. PHP has a specific focus on investing in industries such as Healthcare, Education, Real Estate and Agriculture.

Pioneer Healthcare Partners

Angelus Partners is a venture capital firm that provides growth to innovation.

Angelus Partners

Signifier Medical Technologies

Snoozeal was founded in 2015 in United Kingdom. Co-founder Prof. Dr Anshul Sama, working in a multidisciplinary sleep team, was deeply empathic with many of his patients that were struggling with conventional treatment options that had failed to change in the last two decades. Not dissimilar to practice in many parts of conventional medicine, the emphasis was on treatment of the end result (i.e. splinting the airway open) rather than treating the root cause- collapse of airway due to excessive loss of muscle tone. Over the years Prof Sama came across many devices, all of which had to be worn during sleep, were invariably uncomfortable, only effective when in use and further disrupted the already poor sleep quality.

Signifier Medical Technologies is a UK-based medical device manufacturer focused on developing non-invasive solutions for sleep-disordered breathing conditions like obstructive sleep apnea (OSA) and primary snoring. The company’s flagship device, eXciteOSA, is a daytime device that uses neuromuscular electrical stimulation (NMES) to "exercise" the upper airway muscles, improving their endurance and preventing airway collapse during sleep, which the company claims is the first and only clinically proven medical device to do so.

Membership-based, non-insurance healthcare companies helping maintain a steady state of well being.

Preventive Healthcare

<div>UK-based Signifier Medical Technologies is the developer of the eXciteOSA device for daytime treatment of sleep disordered breathing and snoring. Unlike most companies that offer nighttime sleep solutions, the company distinguishes itself by developing daytime sleep solutions. The company claims that its treatment strengthens weak tongue muscles known to be the root cause of sleep apnea and snoring.</div>

A new industry proving that digital connectivity and mental health can co-exist.

Digital Wellness

Signifier Medical Technologies Announces Milestone Order of 10000 eXciteOSA Devices by Leading Home Medical ...

Signifier Medical Technologies is a UK-based medical device manufacturer focused on developing non-invasive solutions for sleep-disordered breathing conditions like obstructive sleep apnea (OSA) and primary snoring. The company’s flagship device, eXciteOSA, is a daytime device that uses neuromuscular electrical stimulation (NMES) to "exercise" the upper airway muscles, improving their endurance and preventing airway collapse during sleep, which the company claims is the first and only clinically proven medical device to do so.eXciteOSA aims to improve muscle function and can be used by patients while awake, unlike traditional sleep apnea devices. The company has also developed an app that connects with the device to enable the remote monitoring of a patient’s progress. The prescription device is made to be worn daily, for 20-minute sessions over a 6-week period and twice-weekly thereafter.In April 2024, South Carolina's Medicaid program began covering eXciteOSA, expanding access to this innovative therapy.Key customers and partnershipsFollowing FDA authorization through the de novo pathway in February 2021, eXciteOSA launched commercially in the US and has since treated over 10,000 patients as of March 2023. Furthermore, in May 2023, the company announced a partnership with Sunrise, a health tech firm offering AI-powered home sleep testing, aiming to improve patient care through efficient diagnostics and treatments for OSA.Funding and financialsThe company completed a Series D funding round in July 2021, which brought its total funding to USD 58 million. The funds were directed towards the commercialization of its eXciteOSA system.

Cardiomo Care is developing noninvasive wearable devices to alert users and caretakers when there are abnormalities in the heartbeat. The company’s AI engine, trained on existing and growing data sets, can predict potential heart issues up to two hours before they occur, enabling early detection and intervention for arrhythmias and other cardiovascular diseases (CVDs).The company's product, CardiomoPatch, is a waterproof, wearable patch capable of long-term wear with a 10-day battery life. The patch monitors a patient's cardiac data, including ECG outputs, breathing, and skin temperature, and transmits the data via a mobile app for analysis by Cardiomo's AI engine.&nbsp;As of May 2024, the company is yet to commercialize its product and has over 1,600 pre-orders.

Cardiomo Care

Omada is a prevention-focused digital therapeutics startup that helps members achieve health goals through lifestyle changes. It offers four evidence-based, virtual prevention programs for managing hypertension, musculoskeletal (MSK) issues, prediabetes, and diabetes.Omada offers real-time data tracking through connected devices (such as wireless scales, blood pressure, and glucose monitors) and access to personalized coaching sessions via a mobile app as part of its prevention program. It also provides an online community of peers with similar health conditions to discuss challenges and provide support. In May 2021, Omada became the first fully-virtual healthcare provider to earn the National Committee for Quality Assurance’s Population Health Program Accreditation for its type 2 diabetes and type 2 diabetes + hypertension programs.Unlike its peers, Omada operates a performance-based business model where it charges clients an enrollment fee based on the number of users and a performance fee based on how much weight their employees lose. In May 2020, the company acquired virtual physical therapy startup Physera.Key customers and partnershipsAs of May 2024, Omada had more than 1 million members from more than 1,900 enterprise clients across all 50 US states. Its B2B employer and health plan client base include key clients such as American Eagle, Kaiser Permanente, Costco Wholesale, 3M, and Marvin. Additionally, the company has partnered with health systems and hospitals such as Intermountain Healthcare to provide its preventive programs as a covered benefit.In <a href="https://sp-edge.com/updates/15587">January 2023</a>, the company partnered with health service company Castell (a subsidiary of Intermountain Healthcare) to provide its diabetes programs to members from Intermountain Healthcare’s primary care providers in its Utah Medical Group. Further in <a href="https://sp-edge.com/updates/25245">January 2024</a>, the company partnered with Amazon to expand access to its cardiometabolic program.

Omada Health

VillageMD provides primary care services for patients. It also provides tools, technology, and staffing support needed for physicians to deliver high-quality services. VillageMD’s service delivery methods include traditional freestanding clinics, Village Medical at Walgreens co-located clinics, as well as at-home and around-the-clock virtual visits. It also leverages a team-based approach to care where physicians lead nurse practitioners, pharmacists, mental health specialists, and dietitians to offer a holistic care program. The technology of VillageMD includes docOS, an operating system that enables better patient care by connecting various clinical source systems with ongoing patient-generated data coupled with an AI engine to continuously analyze messages to enable patient self-care.The company made several acquisitions to expand its footprint: 1) <a href="https://sp-edge.com/updates/14347">Summit Health</a> for USD 8.9 billion in November 2022, 2) Healthy Interactions, an interactive patient education platform, in February 2022, and 3) <a href="https://sp-edge.com/updates/16968">Starling Physicians</a>, a primary care and specialty care provider, in March 2023.Key customers and partnershipsIn June 2020, VillageMD and Walgreens Boots Alliance announced a collaborative effort to open at least 600 Village Medical centers at Walgreens across more than 30 US markets by 2025. Walgreens invested USD 5.2 billion in VillageMD (from the previously announced USD 1.0 billion), raising its ownership stake to 63% (from 30%).However, as of May 2024, Walgreens had plans to close 160 VillageMD clinics as part of a cost-cutting plan.

VillageMD

Cityblock Health is a value-based healthcare provider focused on delivering comprehensive care to underserved communities, primarily Medicaid and lower-income Medicare beneficiaries. The company combines primary care, behavioral health, and social services to address the complex physical, mental, and social needs of its members.Cityblock's model involves partnering with local community-based organizations and deploying multidisciplinary care teams that include doctors, nurses, behavioral health specialists, and community health workers. These teams provide personalized care through 24/7 access to multi-modal care delivery, including in-home visits, telehealth, and community health hubs.The services of Cityblock are available to members at no additional cost if they are covered by an eligible health plan.Key Customers and PartnershipsAs of May 2024, the company’s services were available in seven states across the US and served over 100,000 members.In May 2024, it partnered with <a href="https://sp-edge.com/updates/29647">Sunshine Health</a> to expand to Florida, and, in <a href="https://sp-edge.com/updates/13270">September 2022</a>, it partnered with MDwise to expand into Indiana. Prior to that, the company had partnered with insurance providers such as ConnectiCare (Connecticut), Tufts Health Plan (Massachusetts), Emblem Health (New York), Healthy Blue (North Carolina), Molina Healthcare (Ohio) and CareFirst (Washington DC).Funding and FinancialsCityblock is a spin-off of Sidewalk Labs, an Alphabet company that incubates and invests in tech companies and products to improve urban infrastructure. It completed a USD 400 million Series D funding round led by Softbank in <a href="https://sp-edge.com/updates/5326">September 2021</a>, valuing the company at USD 5.7 billion. The funds were used to expand its services.

Cityblock Health

Everside Health (formerly Paladina Health) offers preventative care for chronic conditions and primary, mental and occupational healthcare treatments for acute conditions. Patients benefit from around-the-clock access to care, same-day or next-day appointments for in-person, and virtual care visits with zero copays.Everside aims to generate around 17% healthcare cost savings in three years and 31% in five years for its corporate members by leveraging a data-driven approach to care coordination.The company leverages data from past medical records, predictive analytics, and AI in the delivery of preventative care services.Founded in 2010 under the name Paladina Health, the company was rebranded in November 2020 as Everside Health following a merger between three primary care groups (Paladina, Activate Healthcare, and Healthstat). Furthermore, in February 2024, Everside Health merged with primary care provider Marathon Health to form a combined entity that would operate as Marathon Health, and, as of May 2024, the integration was ongoing.Key customers and partnershipPost-merger with Marathon Health, the combined entity would serve 2.5 million patients through over 680 clinics across 41 states.Funding and financialsThe company received its most recent investment in July 2022, amounting to USD 164 million in growth equity funding. The round was led by New Enterprise Associates (NEA). The funds were allocated toward growing its market presence and exploring opportunities for M&amp;A as well as to enhance and improve its product features. Additionally, the firm planned to expand its coverage of specialty care services aimed at individuals, employers, and union organizations.

Everside Health

Platforms offer a subscription-based or B2B-sponsored, evidence-based program for managing a specific long-term health condition.

DPCs offer value-based primary and preventive care services addressing whole-person (social, mental, physical) needs for a fixed monthly or annual fee paid by either the patient, insurance provider, or employer.

Companies offer B2B and D2C evidence-based treatments delivered via software programs to prevent and manage a variety of chronic conditions.

Tools that collect and analyze real-time patient data that supports healthcare providers with clinical decisions,  improves patient outcomes, and reduces medical errors.

Companies offer independent physician practices and hospitals with the tools (patient engagement, care coordination, administrative services) to help manage and improve clinical health outcomes of a defined group of individuals or large populations.

Platforms are used to track and gather patient health-related information via either a connected device or at-home test kits to detect the early onset of disease and identify any abnormalities in readings—but do not include a treatment plan.

To gather large amounts of real-time data for chronic care management, DTx, and patient monitoring

XR used by some startups for chronic pain management

Offers digital means of providing direct primary care, passive remote monitoring, chronic care management, etc.

AI/ML is used in predictive analytics, diagnostics tools, and population management

Offers tailored preventive interventions and treatments to the specific needs and characteristics of each individual

<div>
 
 UK-based Signifier Medical Technologies is the developer of the eXciteOSA device for daytime treatment of sleep disordered breathing and snoring. Unlike most companies that offer nighttime sleep solutions, the company distinguishes itself by developing daytime sleep solutions. The company claims that its treatment strengthens weak tongue muscles known to be the root cause of sleep apnea and snoring.
 
 
 The eXciteOSA device received approval from the US Food and Drug Administration (FDA) in February 2021. The device is expected to be used for 20 minutes per day for a period of six weeks and then twice per week thereafter. It has been clinically proven to reduce obstructive sleep apnea and snoring and improve sleep. The company claims 82% of bed partners reported a reduction in their partners&rsquo; snoring and 98% of the patients reported a reduction in snoring time.&nbsp;
 
 
 Key customers and partnerships
 
 
 In May 2023, the company 
 partnered with Sunrise, a provider of AI-based at-home diagnostic solutions for obstructive sleep apnea, to combine Signifier&rsquo;s &ldquo;eXciteOSA&rdquo; solution with Sunrise&rsquo;s patient management portal.&nbsp;Through this partnership, healthcare providers will be able to better diagnose patients, gather patient data, and provide patients with necessary tools for treatment. 
 
 
 
 
 
 Funding and financials
 
 
 
 In July 2021, the company raised USD 35 million in a Series D funding round for commercialization efforts and further developments and improvements.&nbsp;&nbsp;
 
</div>

Headspace is a digital wellness company that delivers meditation programs through a smartphone app. The company was founded by Andy Puddicombe, a former Buddhist monk, and Richard Pierson, a marketing and brand development professional. In addition to meditation, Headspace offers stress management programs, mindfulness activities, and sleep therapy solutions. Headspace also operates a business-to-business (B2B) focused “Headspace for Work” program with around 1,600 corporate customers as of January 2021, which has seen around 3x growth during 2020. Further, the company operates “Headspace for Health,” a program that develops US Food and Drug Administration (FDA) approved meditation tools to treat chronic diseases.As of January 2023, the company has over 100 million users across 190 countries, with its brands “Headspace for Work” and “Ginger” being used by over 4,000 enterprises including Starbucks, Adobe, Delta Air Lines, Mattel, and Paramount. The company also partners with a health plans, such as Cigna, to provide its services.In January 2022, the company <a href="https://sp-edge.com/updates/7781">acquired Sayana </a>, an AI-powered mental health provider which helps employees manage stress and anxiety, improve sleep and increase productivity. The acquisition was carried out to expand Headspace's services to provide personalized self-care to its users.In June 2022, the company launched a <a href="https://sp-edge.com/updates/11145">new training program for senior leaders </a>and managers to support mental well-being in the workplace.In September 2022, the company <a href="https://sp-edge.com/updates/12918">acquired fellow mindfulness platform Shine </a>for an undisclosed amount. The acquisition enhanced Headspace Health’s offerings by supporting inclusiveness and diversity while also growing Headspace’s member base. Select content from Shine was earmarked to be added to Headspace Health’s content library.In November 2022, the company launched a new platform that combines its product offerings with mental health platform Ginger’s <a href="https://sp-edge.com/updates/5119">an entity it merged with in August 2021 </a>. The platform combines Headspace Health’s meditation and mindfulness services with Ginger’s on-demand coaching, therapy, and psychiatry services, to offer enterprise clients an integrated solution for supporting their employees.In January 2023, the company <a href="https://sp-edge.com/updates/16052">expanded its geographical reach </a>to offer coaching, therapy, and employee assistance-related services to UK headquartered enterprise clients. The company stated it plans on continuing this international expansion into other countries throughout 2023 but did not mentioned specifics.In April 2024, Headspace <a href="https://sp-edge.com/updates/28767">introduced a new mental health coaching service </a>that offered one-on-one support in tackling a wide range of life challenges. The service was available to its direct-to-consumer subscribers at a rate of USD 99.99 per month. The company claimed the experts had been trained to help individuals set realistic goals, initiate new habits, and motivate change while providing them full responsibility for their achievement.In July 2024, the company <a href="https://sp-edge.com/updates/31551">announced that Tom Pickett will be its new CEO</a> and member of the company's board of directors, effective August 12, 2024.Key customers and partnershipsIn June 2023, the company <a href="https://sp-edge.com/updates/19771">extended its partnership with with employee benefit management platform provider Virgin Pulse </a>to integrate its platform with Virgin Pulse’s platform. This integration enables employees enrolled in Virgin Pulse’s health benefit offerings to access the full suite of Headspace’s offerings as a part of Virgin Pulse’s Homebase for Health platform.In March 2024, Headspace <a href="https://sp-edge.com/updates/27330">partnered with Meta </a>to launch "Headspace XR," available for an upfront fee of USD 30. Headspace XR provides guided mindfulness and meditation exercises led by the same instructors familiar to regular Headspace users. The exercises cover activities such as breathing techniques, body scans, and mood tracking. Additionally, it incorporates a social element, including interactive metaverse-style gaming in vivid environments.In June 2024, Headspace <a href="https://sp-edge.com/updates/30378">partnered with Uwill</a>, a mental health platform for colleges and students, to integrate Headspace's wellness services into Uwill's existing portal. The collaborative effort will allow Uwill's Urise program to incorporate Headspace's services, primarily meditation, yoga, and mindfulness offerings.Most recently, in August 2024, Headspace <a href="https://sp-edge.com/updates/21452">partnered with Castell</a>, a value-based care (VBC) subsidiary of Intermountain Healthcare, to offer mental health services to members of select insurance plans in Utah. The partnership aimed to improve health outcomes by providing personalized mental healthcare to members. Through the partnership, Castell began refering eligible members to Headspace for behavioral health coaching and therapy, giving them access to a team of coaches and licensed therapists through an outcomes-based payment model.

Headspace

<div>
 
 Calm is a digital wellness company which offers guided meditations to make people happy as well as mindfulness and sleep programs through a smartphone app. Its audio content is designed to strengthen mental fitness and address mental health challenges such as stress, anxiety, insomnia, and depression. The company started out as a website in 2011 where users were trained to stare at a screen and listen to waves on a beach for two minutes without touching their mouse. In February 2013, more content was added and the company launched a mobile app. Calm was named by Apple as the 2017 iPhone App of the Year and received Editors' Choice certification by Google in 2018. Calm offers content in English, Spanish, French, and German and operates Calm Business, a business-to-business (B2B) covering over 10 million employees as of March 2022. 
 
 
 
 
 Calm gained significant traction in 2020 during the Covid-19 lockdowns. It became the most downloaded digital wellness app during April 2020 with 3.9 million downloads worldwide, including 1.6 million downloads in the US. Kaiser Permanente, a large managed care service provider, provided Calm free for its 12.4 million members in May 2019. Calm also partnered with CNN on the 2020 US presidential election day to play the sound of rain hitting leaves on air, a marketing effort that went viral on social media.
 
 
 As of December 2020, Calm has reported over 100 million app downloads (compared with over 40 million in early 2019 and over 80 million as of May 2020) and was valued at USD 2 billion. 
 
 
 In October 2022, the company 
 <a href="https://sp-edge.com/updates/13853">
 launched a new clinical mental health offering
 </a>
 called &ldquo;Calm Health,&rdquo; marking its expansion into the mental health space. The new solution provides condition-specific programs designed to bridge mental and physical care and includes tools for communication with providers and medication tracking. This solution was created for the company by Ripple Health, which was 
 <a href="https://sp-edge.com/updates/8246">
 acquired by Calm
 </a>
 in February 2022. 
 
 
 Key customers and partnerships
 
 
 As of December 2022, the company has partnered with over 20 brands to collaborate and provide its services through sales partnerships. These brands include Xbox, Amazon, YouTube, Adidas, Fitbit, and American Express. 
 
 
 Funding and financials
 
 
 In December 2020, Calm raised USD 75 million in a series C funding round led by Lightspeed Venture Partners doubling it&rsquo;s valuation to USD 2.0 billion. Calm planned to use the funding to expand operations globally and broaden its B2B offerings.
 
</div>

Calm

<div>
 
 Simple Habit is a guided meditation service provider, which offers bite sized, five-minute long meditation sessions through an app targeting people with busy schedules. The company also offers mindfulness, sleep, and wellness programs. As of November 2020, Simple Habit offered over 2,000 sessions designed to help users sleep, reduce anxiety, and get over relationship issues. The content is organized by occasion, such as commuting, going to sleep or preparing for a meeting. 
 
 
 In June 2022 the company launched its Sleep Habit app, a virtual sleep clinic that helps users improve the quality of their sleep. The app uses clinically validated approaches to improve sleep quality and treat issues such as insomnia via methods such as cognitive behavioral therapy. 
 
 
 As of September 2022, Simple Habit claims to have a 7 million users between both of its apps. 
 
 
 
 
 In November 2018, Simple Habit raised USD 10 million in a Series A round led by Foundation Capital, bringing the company’s total funding to USD 12.6 million. The company used the funds to expand its library of guided meditation sessions and to add audio content led by therapists and executive coaches. As of late 2018, the app was reported to sign up as many as 30,000 new users per week. As of November 2020, Simple Habit reported having helped helped over five million people reduce burnout through its app’s services.
 
</div>

Simple Habit

<div>
 
 Insight Timer is a company which offers guided meditation, yoga, and sleep programs through a smartphone app. It also offers free interactive live sessions with teachers, performers, and therapists through the app and web. The company’s business-to-business (B2B) offering, “Circles for teams”, targets enterprise customers to help bring employees together to practice group meditations, chat with each other, and recommend content. In October 2020, Insight Timer began offering free, daily live yoga classes from instructors based on a pay-what-you-can model.
 
 
 
 
 As of October 2020, Insight Timer featured around 8,000 meditation teachers providing over 70,000 free tracks on guided meditations in 50 languages as well as 5,000 music tracks. The company has also claimed that it ranks first in the US among meditation apps in terms of the time spent by users with Insight Timer boasting 63% of the time spent on meditation apps as of 2018.
 
 
 
 
 The majority of the content is available for free, and users can sign up for a premium version at a price of USD 9.99 per month or USD 59.99 per year. Premium users get access to content such as Insight courses and the ability to download content.
 
 
 
 
 In January 2020, the company raised USD 27.4 million. As of November 2020, the monthly operating cost of the company is reported to be around USD 1 million and Insight Timer has failed to break even as of the end of 2020. The founder attributes the significant growth of the company to its free content and has advocated against moving too much of its content behind the premium subscription paywall. As of November 2020, the app had a 16% 30-day retention rate, more than double the average retention rate of 7.7% for top 100 apps in Apple’s App Store. As of November 2021, the company has 19 million users. 
 
</div>

Insight Timer

<div>
 
 Big Sky Health is the developer of the Oak Meditation breathing app. Oak Meditation offers guided and unguided meditations, sleep meditations, meditation timers, yogic exercises for breathing, animated instructions, and music tracks. The company is headed by Mike Maser, an entrepreneur who was diagnosed with stage IV cancer. Most of the companies services are offered free of charge with in-app purchases ranging from USD 5.99 to USD 38.99.
 
 
 
 
 In addition to Oak meditation, Big Sky also offers a fasting app called Zero and an alcohol moderation app called Less. In May 2020, Big Sky raised USD 8 million in Series A funding in a round led by Greycroft with participation from existing investors True Ventures and Trinity Ventures, bringing the company’s total funding to USD 12.2 million. Big Sky Health expects to use the funds to expand its staff and boost customer acquisition.
 
</div>

Big Sky Health

Apps that provide relaxation, stress reduction and non-therapeutic mental health support via meditation-related techniques.

These apps aim to increase users’ body and brain functions including memory and attention to detail with microlearning, gamification, and journaling techniques.

Helps users analyze and address sleep disorders with wearable tech, music and sound therapy, and storytelling.

Apps that provide virtual training programs, track workouts, and provide guides for nutrition.

Some digital wellness providers provider VR/AR experiences for meditations

Some companies offer personalized care/meditation plans, workout regimens, or treatments for sleep disorders

Offers app-based platforms that improve health and wellness

Signifier Medical Technologies

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