<div>
  <p>
  </p>
  <ul>
    <li>
      <p>
        The National Cancer Center (NCC) Japan, Precision Medicine Asia (PREMIA), and Paradigm Health have partnered to launch LC-SCRUM-CD, a nationwide clinical trial network for cancer research in Japan.
      </p>
    </li>
    <li>
      <p>
        The collaboration will leverage LC-SCRUM-Asia's network of 150+ hospitals for cancer genomic screening. PREMIA will manage the data platform, and Paradigm will provide its end-to-end clinical trial platform. The partnership aims to increase global pharmaceutical-sponsored trials in Japan while reducing the operational burden on healthcare providers.
      </p>
    </li>
    <li>
      <p>
        The initiative builds upon NCC Hospital East's clinical trial capabilities, which currently run over 500 studies annually. It will enable more efficient patient selection for clinical trials through the integration of genetic analysis results and clinical data.
      </p>
    </li>
    <li>
      <p>
        <b>Analyst QuickTake: </b>
        This is the second partnership Paradigm has established in Japan. Earlier this year, Paradigm 
        <a href="https://sp-edge.com/updates/32922">
          partnered with Fujitsu
        </a>
        , a global technology company, to improve clinical trials and address drug loss in Japan. The company appears to be continuing its global expansion strategy, focusing on Japan. 
      </p>
    </li>
  </ul>
  <p>
  </p>
</div>


<div>
  <p>
    <a href="https://www.paradigm.inc/news/ncc">
      Press release
    </a>
  </p>
  <p>
    <a href="https://hitconsultant.net/2024/11/06/japans-national-cancer-center-selects-paradigm-for-nationwide-clinical-trial-network/">
      HIT Consultant
    </a>
  </p>
</div>


Clinical Trial Technology

ANALYST_QUICK_TAKE

PROMINENT_CATEGORY

<div>
 
 <p>The National Cancer Center (NCC) Japan, Precision Medicine Asia (PREMIA), and Paradigm Health are teaming up to initiate LC-SCRUM-CD, a broad-scaled clinical trial network for cancer research in Japan. This partnership will utilize LC-SCRUM-Asia's existing network of over 150 hospitals, specifically for cancer genomic testing.</p>
 <p>PREMIA will handle the data platform management, whilst Paradigm brings to the table their comprehensive clinical trial platform. The alliance aims to increase the frequency of international pharmaceutical-sponsored trials in Japan, simultaneously alleviating the operational stress on healthcare providers.</p>
 <p>This initiative is a build upon NCC Hospital East's clinical trial capabilities, with already existing annual studies exceeding 500. The collaboration will facilitate a more efficient patient recruitment for clinical trials by amalgamating the results from genetic analysis with clinical data.</p>
 
</div> <p><b>Analyst QuickTake:<br>
 </b> This is the second partnership Paradigm has established in Japan. Earlier this year, Paradigm <a href="https:<br>
//sp-edge.com/updates/32922"> partnered with Fujitsu </a> , a global technology company, to improve clinical trials and address drug loss in Japan. The company appears to be continuing its global expansion strategy, focusing on Japan.</p>

NCC Japan partners with PREMIA and Paradigm to establish nationwide cancer clinical trial network

Empowering Tomorrow's Innovations with Generative AI Infrastructure

Generative AI Infrastructure

INCUMBENTS_PRESENT

<div>
 <p>At the re:Invent 2024 conference held by Amazon, Apple announced their use of Amazon's custom AI chips called Inferentia and Graviton. These chips are used for Apple's cloud services such as Siri, Apple Maps, and Apple Music. This implementation resulted in a 40% efficiency boost in the company's search services.</p>
 <p>In addition, Apple is set to assess the performance of Amazon's new Trainium2 chip which will be used for pretraining of Apple's AI models, including Apple Intelligence. This new partnership is forecasted to bring about an efficiency improvement of up to 50%.</p>
</div> <p><b>Analyst QuickTake:<br>
 </b> The disclosure of this partnership is unusual for Apple, which typically keeps such details under wraps compared to its Big Tech peers. Additionally, the move underscores AWS’ strengths in the competitive cloud AI market, positioning it against rivals like Microsoft Azure and Google Cloud. AWS’ growing credibility is further bolstered by its <a href="https:<br>
//sp-edge.com/updates/36441"> investment </a> with Anthropic for GenAI model training using its chips.</p>

Apple discloses use of AWS GenAI chips at re:Invent 2024 conference

<div>
 <p>Amazon Web Services (AWS) has introduced an innovative tool called Automated Reasoning checks as part of its Bedrock model hosting service. This tool has been purposed to mitigate AI hallucinations and uses a validation system that checks model responses against information supplied by customers.</p>
 <p>These Automated Reasoning checks function by comparing AI responses with ground truth data from customers. These checks produce rules which can be honed and applied to various models. While generating responses, they carry out cross-verification and at the same time display correct responses in conjunction with possible falsehoods for contrast.</p>
 <p>AWS declares that it is the first among major cloud providers to offer a safeguard effect against AI hallucinations. Moreover, it empowers clients to establish as well as personalize safety, privacy and truthfulness within an all-in-one solution. PricewaterhouseCoopers (PwC) is already incorporating this tool in producing AI assistants for its clientele. However, AWS hasn't shared any data that demonstrate the tool's reliability.</p> 
</div> <p>Analyst <b>QuickTake:<br>
 </b> The update builds on AWS' existing hallucination detection capabilities, initially having Guardrails for Amazon Bedrock in <a href="https:<br>
//sp-edge.com/updates/24413"> November 2023 </a> . In <a href="https:<br>
//sp-edge.com/updates/31381"> July 2024 </a> , the company announced contextual grounding checks (to detect hallucinations in model responses based on a reference source and user query) and ApplyGuardrail API, which allows customers to evaluate input prompts and model responses against configured safeguards for any foundation model.</p>

AWS launches Automated Reasoning checks to combat AI hallucinations

Buy Now, Pay Later

<div>
<p>Buy now, pay later (BNPL) infrastructure solutions developer, Roonyx, has introduced new features including a virtual card management system, superior know-your-customer (KYC) integration, and an improved interface to facilitate secure online and offline transactions.</p>
<p>With the new virtual card feature, users can instantly create cards with time-based restrictions, manage payment methods, and have the option to block or restart cards. Partnering with providers revolutionizes Roonyx's KYC capabilities with identity verification, document validation, and address confirmation. The platform's new interface exhibits transaction details with enhanced lucidity, simplifying purchase management.</p>
<p>Roonyx asserts that these advancements give businesses boosted fraud protection, virtual card options for customer engagement, and resources for sales data analysis. The company's future plans point to the introduction of customizable limits, broadening of KYC for global markets, and development of superior analytical tools.</p>
</div> <p><b>Analyst QuickTake:<br>
 </b> Today’s updates follow the launch of Roonyx's <a href="https:<br>
//sp-edge.com/updates/34395"> BNPL platform </a> two months ago. The enhanced platform offers businesses a comprehensive, ready-made solution for implementing BNPL capabilities. The initial launch introduced a ready-made and comprehensive infrastructure solution to meet the diverse needs of businesses, streamlining the adoption of BNPL services.</p>

Roonyx releases enhanced BNPL platform to facilitate secure transactions

<div>
 <p>The 2024 re:Invent conference saw AWS launch the next version of Amazon SageMaker, which is an ML platform that combines data analytics, AI capabilities, and model development. Currently, SageMaker Unified Studio is in the preview phase.</p>
 <p>Comprising three main components: SageMaker Unified Studio, SageMaker Catalog, and SageMaker Lakehouse, the platform includes functions from Amazon Bedrock, EMR, Redshift, AWS Glue and existing SageMaker Studio. It also includes an Amazon Q Developer assistant for professional code and SQL generation tasks.</p>
 <p>According to AWS, the unified platform will enhance enterprise efficiency substantially. Predicted outcomes include a 50% reduction in time to access analytics and AI capabilities for NatWest Group and a 40% reduction in data processing time for Roche. Further integrations with SaaS applications like Zendesk and SAP negate the need for intricate data pipelines.</p>
 
</div>

AWS announces next generation of SageMaker platform at re:Invent 2024

Quantum information processing is slowly becoming a reality, ushering in a new technological era.

Quantum Computing

<div>
 <p>The Irish quantum computing company Equal1 has introduced a multi-tile quantum controller chip that belongs to its UnityQ Quantum-System-on-Chip platform. The chip functions at 300 millikelvin temperatures and uses Arm's Cortex core microprocessors, a British semiconductor company.</p>
 <p>The quantum controller chip is equipped with AI-supported qubit adaptive error correction, adjusted for each tile under the control of Arm's Cortex processor. This chip showcased high performance metrics on a six-qubit array, reaching 99.4% single-qubit fidelity with a gate speed of 84 nanoseconds, and a two-qubit fidelity of 98.4% with a gate speed of 72 nanoseconds.</p>
 <p>Equal1 asserts that their new controller chip will help to scale up to millions of orchestrated qubits on a single chip. Additionally, it will enable real-time error correction and provide the flexibility to use both present and future error correction algorithms. The technology can be manufactured utilizing existing silicon infrastructure and conventional foundries, according to Equal1.</p>
 
</div>

Equal1 launches quantum controller chip for cryogenic computing

AI, robotics, and IoT to streamline the flow of goods and information

Logistics Tech

<div>
 <p>Extoec has formed a partnership with BlueStar, a provider of digital identification and mobility solutions, to introduce warehouse automation solutions in BlueStar's distribution centers throughout Europe and the US.</p>
 <p>The focus of the partnership is the implementation of Exotec's Skypod system, featuring 20 Skypod robots, racking with 23,000 bins, three picking stations, and one bin interface. This system has decreased warehouse traffic by 60% and improved order-picking efficiency at BlueStar's EMEA Distribution Centre in Eindhoven.</p>
</div> <p><b>Analyst QuickTake:<br>
</b> Today’s partnership adds BlueStar to Exotec’s growing list of customers, which also includes <a href="https:<br>
//sp-edge.com/updates/35243"> Auchan Retail Luxembourg </a> , <a href="https:<br>
//sp-edge.com/updates/26080"> Lane Automotive </a> , <a href="https:<br>
//www.prnewswire.com/news-releases/first-supply-partners-with-exotec-to-boost-its-operational-capabilities-and-support-business-growth-302150787.html"> First Supply </a> , and <a href="https:<br>
//media.renaultgroup.com/renault-group-positions-itself-at-the-forefront-of-innovation-in-automotive-logistics-with-exotec/"> Renault Group </a> .</p>

Exotec partners with BlueStar to deploy Skypod warehouse automation system

Additive manufacturing makes objects by systematically adding material via a CAD program

Additive Manufacturing

<div>
 <p>Metals additive manufacturing provider Amaero International has formed a three-year supply agreement with Perryman Company, a titanium parts provider. The agreement stipulates that Perryman will function as the primary source of titanium alloy bar feedstock for Amaero's production of premium spherical powder. The agreement includes specific pricing for the year 2025, which will experience annual increases and fluctuating surcharges based on the market rates of Ti64. The set pricing relates to yearly minimum order requirements of 45 metric tons in 2025, and 100 metric tons for both 2026 and 2027.</p>
</div> <p><b>Analyst QuickTake:<br>
 </b> Amaero has been actively ramping up its production capacity in the US over the past few months <b>. </b> This news comes only two months after the company <a href="https:<br>
//sp-edge.com/updates/33656"> raised USD 16.9 million </a> in an institutional placement, which it earmarked for purchasing capital equipment, including a second atomizer, and improving its Tennessee headquarters.</p>

Amaero enters long-term supply agreement with Perryman

<div>
 <p>3D printing company, Raise3D, has introduced six new resins for its DF2 Resin digital light processing (DLP) printer, bringing its total product range to 15 resins. These new products have been designed for high-performance engineering prototyping and low-volume production.</p>
 <p>The new offerings are Raise3D Draft Grey V1 for high-speed prototyping, Forward AM Ultracur3D EL 4000 with Shore 90A hardness for hard products, Forward AM Ultracur3D EL 60 for elastic projects, and three Henkel LOCTITE products: 3D 3843 for impact strength, 3D PRO410 for high resolution, and 3D PRO417 for high strength applications.</p>
</div>

Raise3D launches six new resins for DF2 DLP solution

<div>
 <p>Anzu Partners LLC, a technology investment firm, has agreed to acquire voxeljet AG, a provider of large-format 3D printers and on-demand 3D printed parts, for EUR 20 million (~USD 21 million).</p>
 <p>Following the acquisition, Anzu's managing partner Whitney Haring-Smith will become chair of the board of directors, while current CEO Rudolf Franz will continue to lead the business.</p>
 <p>The transaction, expected to close in March or April 2025, includes a "go-shop" period until January 12, 2025, allowing voxeljet to consider alternative acquisition proposals.</p>
</div>

Anzu Partners acquires voxeljet for EUR 20 million

Managing employee health-related benefits

Health Benefits Platforms

<div>
 
 <p>Soda Health, a benefits management provider, has raised USD 50 million in a Series B funding round. This was led by General Catalyst, along with contributions from Bruce Broussard, Lightspeed Venture Partners, Define Ventures, Qiming Venture Partners US, and SVB Capital, increasing the company's total raised funds to USD 81 million.</p>
 <p>The funding will be utilized to scale operations, introduce new data products, and develop capacities to new compliance management systems. This includes CMS-compliant benefit categories and gap closure strategies. The ambition is to establish risk-based structures with Medicare Advantage and Medicaid plans and widen CMS-compliant benefit offerings.</p>
 <p>As of December 2024, Soda Health's Smart Benefits platform operates in over 50,000 retail locations in the US, including prominent chains such as Kroger, Albertsons, CVS, and Hy-Vee. In the same year, over 33 million seniors relied on Medicare Advantage, accounting for USD 131 billion in supplemental benefits and reward dollars.</p>
 
</div>

All Updates

NCC Japan partners with PREMIA and Paradigm to establish nationwide cancer clinical trial network

Apple discloses use of AWS GenAI chips at re:Invent 2024 conference

AWS launches Automated Reasoning checks to combat AI hallucinations

Roonyx releases enhanced BNPL platform to facilitate secure transactions

AWS announces next generation of SageMaker platform at re:Invent 2024

Equal1 launches quantum controller chip for cryogenic computing

Exotec partners with BlueStar to deploy Skypod warehouse automation system

Amaero enters long-term supply agreement with Perryman

Raise3D launches six new resins for DF2 DLP solution

Anzu Partners acquires voxeljet for EUR 20 million

Soda Health raises USD 50 million in oversubscribed Series B funding to scale operations

Clinical Trial Technology

NCC Japan partners with PREMIA and Paradigm to establish nationwide cancer clinical trial network

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