SETsquared is a collaborative partnership that supports enterprise activities, spin-outs, licensing, and incubation in tech startups. This partnership between the universities of Bath, Bristol, Exeter, Southampton, and Surrey also works with the industry through research collaboration and consultancy.  SETsquared was founded in 2001 and is based in the United Kingdom.

SETsquared

Bristol Private Equity Club is an investment firm that invests in its members with businesses in the schemes SEIS and EIS venture capital.

Bristol Private Equity Club

Green Angel Syndicate is a provider of investors and projects internationally. The company specializes in this novel strategy for combating climate change. They look for, evaluate, and pick the inventions that will have an impact, and then they invest in them to help them grow.

Green Angel Ventures

SCVC is a leading UK emerging manager, focused on early-stage deep tech start-ups spinning out of the UK's world-leading academic institutions. Building the VC firm they wished they had as founders, the SCVC team’s mission is to create global impact for the health of people and the planet, via partnering with exceptional technical founders leveraging deep tech. SCVC is comprised of distinguished exited innovators, scientists & engineers who have backed multiple deep tech spin-outs. SCVC is the official venture arm of Science Creates (SC); leveraging this renowned UK ecosystem that has already incubated over 100 startups.  We invest in advanced technologies from biotech to quantum tech, partnering with companies aligned with our mission of improving the health of people and the planet. We’re a team of deep tech nerds and serial entrepreneurs that backs like-minded founders wanting to change the world.  We are the official VC arm of Science Creates. Being part of Science Creates plugs you into an ecosystem of specialist Incubators, Investment, Partners and Programmes, all designed and curated for deep tech start-ups. We are building the VC firm we wished we had as founders.

SCVC

OnePlanetCapital is more than an investment house, it’s part of a movement. Radical venture capital focused on unlocking the positive impact of early stage companies as they grow. Our team is spearheading the green industrial revolution and disrupting the status quo to create a positive global impact.

One Planet Capital

Blackfinch Ventures invests across sectors in fledgling companies with strong ideas and solid management teams. It provides initial and follow-on funding to start-ups, those looking to grow to the next level, and scale-ups. It then works closely with investee companies over many years, providing assistance and guidance to help businesses succeed.

Blackfinch Ventures

Maven Capital Partners is an independent alternative asset manager, with over £415m of assets under management. Maven was formed in 2009 after a buyout of the Aberdeen Asset Management private equity business, and operates from a nationwide network of regional offices.  They provide flexible equity and loan finance packages to UK SMEs, on behalf of a range of client funds, as well as funding for well-researched property development projects. They also offer attractive investment opportunities for investors including tax-efficient investment into VCTs, and direct co-investment in private equity and property transactions. Maven is one of the UK’s most active private equity managers in the lower mid-market, investing for a range of client funds including six Venture Capital Trusts (VCTs) and a number of regionally focused funds delivering equity and debt finance. They offer a range of flexible funding solutions for entrepreneurial SMEs at any stage of the business growth cycle, with the ability to commit as little as £100,000 of development capital or as much as £15 million to support an MBO.

Maven Capital Partners

QantX

Evenlode Foundation

The intersection of science, technology and ambition is where you’ll find Kadmos Capital, with our track record of successful tech investments and instinct for identifying the most exciting entrepreneurs. Our optimism isn’t shaken by the daunting challenges we face in an unstable world, it is strengthened. The biggest problems demand the most ambitious and ingenious solutions. With the pace of change now faster than ever, it’s vital to back the high-impact technologies that will deliver those solutions. At Kadmos Capital, that is where we are invested.

Kadmos Capital

Green Angel Ventures is the reference early-stage investor for UK climate innovation.

Kelpi

Kelpi is a sustainable biotech start-up bio-refining seaweed to make bioplastic packaging that is marine-safe and home-compostable.

Kelpi, based in England, is a biotech company that creates biopolymers from seaweed to create bioplastics for compostable food packaging. As a result, the company claims that each piece of packaging reduces fossil fuel demand and carbon dioxide emissions. According to the company, its bioplastic technology is marine-safe, carbon-neutral, and resistant to water, oxygen, grease, and acid.

Earth-friendly biotech solutions for the textile, packaging and construction industries.

Bio-based Materials

Kelpi Secures £4.3M in Oversubscribed Round to Replace Plastic with Seaweed Coating in Food & Cosmetics ...

Kelpi, based in England, is a biotech company that creates biopolymers from seaweed to create bioplastics for compostable food packaging. As a result, the company claims that each piece of packaging reduces fossil fuel demand and carbon dioxide emissions. According to the company, its bioplastic technology is marine-safe, carbon-neutral, and resistant to water, oxygen, grease, and acid. Kelpi is currently leading a collaborative R&amp;D project to create a specialist compostable bioplastic film with a strong oxygen barrier that outperforms fossil fuel plastics even in boiling water at high pressure. In <a href="https://sp-edge.com/updates/30057">May 2024</a>, the company announced plans for a commercial launch of its packaging by mid-2025. Key customers and partnerships In March 2021, the company collaborated with the University of Bath to leverage research facilities and expertise to accelerate the testing of its biopolymer composite materials. In addition, the company works closely with Innovate UK, the HM Government, EU European Regional Development Fund, and the West of England Combined Authority. Funding and financialsIn <a href="https://sp-edge.com/updates/16153">February 2023</a>, the company raised more than GBP 3 million (~USD 3.7 million), led by Science Creates Ventures and Green Angel Syndicate, to conduct manufacturing pilots for its proprietary coatings for paper and cards. The round includes a GBP 665,000 grant funding from Innovate UK’s Combined Investor Partnership. In <a href="https://sp-edge.com/updates/30057">May 2024</a>, the company raised GBP 4.3 million (~USD 5.5 million) to scale up operations.

<div>
 
 Bolt Threads manufactures vegan &ldquo;spider&rdquo; silk and mycelium-based materials. Bolt Threads develops isolated silk proteins from proteins inspired by spider silk through a yeast fermentation process. The company&rsquo;s Microsilk products are sold under its clothing brand, Best Made Co. The company has also developed another biomaterial using mushroom-based mycelium, an alternative leather product branded as Mylo, which was expected to be produced on a larger scale.&nbsp;
 
 
 In September 2021, Bolt Threads announced its plans to produce Mylo on a commercial scale by the end of 2022 and expected to collaborate with mushroom farmers to heighten its mycelium crops. Though the company reported 
 <a href="https://sp-edge.com/updates/19867">
 halting production of Mylo
 </a>
 in June 2023 due to inflationary pressure and lack of funding, in October 2023, the company announced entering a 
 <a href="https://sp-edge.com/updates/22431">
 SPAC deal
 </a>
 to go public on the Nasdaq.&nbsp;
 
 
 For its Microsilk product, Bolt had a production capacity of 32,000 sq ft per annum as of 2018. Since Microsilk remains significantly more expensive than traditional silk, the founders were seeking ways to scale up.&nbsp;
 
 
 Key customers and partnerships
 
 
 For its Microsilk product, Bolt Threads launched its first collaboration in 2017 with fashion designer Stella McCartney and introduced its second prototype in the form of a biodegradable tennis dress.
 &nbsp;
 
 
 The leather alternative Mylo has been used in collaborations with Stella McCartney, Seattle-based leather bag manufacturer Chester Wallace, and Canadian athletic apparel retailer Lululemon. In October 2020, the Mylo Consortium was also formed including Adidas, Stella McCartney, Kering, and Lululemon, who collectively have made a seven-figure investment into Bolt Threads to produce Mylo. In return for their investments, these brands would have access to a large supply of the product.&nbsp;
 
 
 Stella McCartney has been experimenting with Mylo to create clothing prototypes with plans to use the material in upcoming collections. Adidas used Mylo to produce high-performance footwear for the first time in April 2021 by making a vegan version of its &ldquo;Stan Smith&rdquo; sneaker design that dates back to 1965 and had plans to expand the use of Mylo material in its other products including handbags, wallets, shoes, jackets. In February 2022, 
 <a href="https://sp-edge.com/updates/8404">
 Lululemon
 </a>
 launched a Mylo-based yoga bag collection, which included a multipurpose yoga bag and a storage bag for workout gear. Mylo was also used by Danish luxury brand Ganni for the launch of its limited edition Mylo-based wallet range and one-of-a-kind saddle-bags in June 2022. Ganni&rsquo;s partnership with Bolt Threads included plans to release more Mylo-based products in Q1 2023. With growing demand for its Mylo product, 
 <a href="https://sp-edge.com/updates/8884">
 in February 2022, 
 </a>
 the company partnered with Mycelium Materials Europe (MME) for the commercial production of Mylo but had not been able to materialize its plans.
 
 
 Funding and financials
 
 
 The company&rsquo;s last funding round was a USD 123 million Series D in January 2018 led by Baillie Gifford. The funds were used to commercialize the company&rsquo;s Microsilk&nbsp;products.
 
 
 
</div>

Bolt Threads

MycoWorks is a manufacturer of alternative leather using mushroom-based fungi. Its proprietary brand, Reishi, is manufactured using a patented process called “Fine Mycelium”, which uses fungi’s capacity to bind to itself and carbon-based materials in producing durable three-dimensional material. The benefits of Reishi, according to MycoWorks, include its tensile strength (the force needed to pull material to its breaking point) at 10 Megapascals (MPa), compared to the average cowhide tensile strength of 8.5 MPa. Reishi is also customizable (in terms of sizing and specifications) allowing growing direct-to-design products that eliminate waste from cutting and trimming.Mycoworks operates three Reishi plants as of January 2022. The third plant in California has an annual production capacity of 80,000 sq ft of material per year, increased the company’s production tenfold, and reportedly reached a milestone of producing 10,000 trays of Fine Mycelium after a year of operation. The company is also building a new USD 107 million worth manufacturing facility in Union, South Carolina, with operations expected to commence in 2023. The new facility reportedly is expected to produce several million sq ft of Fine Mycelium per year. In August 2023, the company announced opening a <a href="https://sp-edge.com/updates/20757">136,000 square foot plant </a>&nbsp;which will produce Reishi that has been embraced by luxury brands like Hermès and Ligne Roset for various applications and was expected to begin operation on September 20, 2023.Reishi remains in the prototype development and testing phase. The company announced that the material is currently being tested in clothing, shoe, wallet, and handbag design. Key customers and partnershipsThe company indicated in November 2020 that the first luxury fashion and footwear products containing Reishi will be launched in partnership with leading fashion and footwear brands in the coming months. MycoWorks also partnered with Hermès, the French luxury goods manufacturer, in March 2021 to use a material named “Sylvania”(a Fine Mycelium-based material developed by the two companies over three years) in a sustainable version of Hermès’s “Victoria” travel bag, by the end of 2021. In <a href="https://sp-edge.com/updates/24584">November 2023</a>, the company partnered with YUME YUME for interactive Reishi-based installation at Stedelijk Museum. Funding and financials<a href="https://sp-edge.com/updates/7804">In January 2022</a>, MycoWorks raised USD 125 million in a Series C funding round led by Prime Movers Lab. The funding was expected to accelerate commercial production of Reishi and support in R&amp;D, technology development, and hiring new employees.

MycoWorks

Checkerspot is a manufacturer of microalgae-based performance materials which are used to produce consumer products, including skis and surfboards. The company modifies microalgae’s genes to derive new molecular building blocks and then bioengineers production of consumer products. Microbes are optimized to biomanufacture unique, natural structural oils that were previously not accessible on a viable, commercial scale. The company’s primary focus is on high-performance polyurethanes and coatings made from bio-based oil via fabrication.The company’s commercialized products include Algal Core (a light-weight urethane-based composite) and Algal Wall (cast urethane), both products are offered under the WNDR Alpine brand while algal oil is sold under the miDori bioWick. In February 2021, WNDR Alpine, Checkerspot’s outdoor brand, received the B Corp Certification, private certification granted to for-profit companies by the B Lab, a global non-profit organization formed to support the movement of using businesses as a force for good. Key customers and partnershipsThe company has partnered with Beyond Surface Technologies (BST) to commercialize miDori BioWick, an algal oil used in BST’s wicking textile finish. As of August 2020, the company’s co-development partners also included W.L. Gore and DIC Corporation.Funding and financialsIn its latest funding round in <a href="https://sp-edge.com/updates/16362">February 2023, </a>Checkerspot raised USD 55 million in Series C funding led by ArrowMark Partners to accelerate the development and commercialization of biobased alternatives for everyday products and expand into markets, such as industrial applications, personal care, and food and nutrition.

Checkerspot

Mi Terro converts milk waste into sustainable yarn, using a self-developed technology known as Pro-Act that extracts casein protein molecules from milk. The protein is purified and undergoes a dynamic flow shear spinning process, converting the casein to sustainable fiber. The resulting yarn is claimed to be three times softer than cotton and has applications in textiles, food packaging, bedding, personal care, and medical sectors. Mi Terro has also developed a limited-release ocean-waste duffle bag. Key customers and partnershipsThe company has partnered with Nike, Danone, Toyoshima, DFA, Mitsubishi, Lair East Labs, Dole, Budweiser, and Harada. In <a href="https://sp-edge.com/updates/23179">October 2023</a>, the company partnered with Lipton to develop dissolvable tea pods. Funding and financialsThe company completed two rounds of funding in 2020, raising USD 100,000 in January 2020 and USD 50,000 in March 2020. In January 2021, the company also won the Meda Million Dollar Challenge and received a USD 300,000 prize. In March 2022, the company raised USD 1.5 million in a Seed round led by Astanor to scale up production.

Mi Terro

Modern Meadow develops collagen-based materials from plant proteins, using a range of biofabrication processes including the creation of bio alloys, solution dyeing, protein design, and fermentation. The focus of the company is on the luxury branded market with its fully biodegradable proprietary brand, “ZOA”. Modern Meadow also reports that it is developing “Bioleather1 (BL1)”, an alternative to chrome tanned bovine leather made using its proprietary BioAlloy process. According to research published by the company in <a href="https://sp-edge.com/updates/8431">February 2022 </a>, BL1 reduces greenhouse gas emissions by 80% and 20% compared to traditional and synthetic leather respectively. It also reduces water consumption from groundwater sources, land use, and the subsequent degradation of water bodies during the process by 95% compared to conventional leather production.In April 2020, Modern Meadow announced plans to commence commercial production later that year and was actively looking for manufacturing partners. As of the same date, Modern Meadow employed between 70-90 staff at its 72,000 sq ft factory in New Jersey.Key customers and partnershipsModern Meadow announced a partnership with Evonik in March 2018, to develop and scale-up the commercial production of fermentation-based products.In April 2021, the company reported that it would announce collaborations with fashion brands and industry partners during the following six to nine months. In <a href="https://sp-edge.com/updates/15657">January 2023 </a>, Modern Meadow partnered with Taiwan-based sustainable fabric company, Singtex to develop biomaterials for various applications, beginning with a sustainable, waterproof, membrane-based material for the outdoor apparel market. In <a href="https://sp-edge.com/updates/16786">February 2023 </a>, the company partnered with US luxury brand, Tory Burch, to launch Tory Burch’s first plant-based leather alternative tote, the Ella Bio, powered by Modern Meadow technology, Bio-Alloy.In June 2023, it also formed a strategic partnership with <a href="https://sp-edge.com/updates/19178">Navis TubeTex </a>, a provider of textile machinery, to develop a sustainable textile manufacturing process. During the same month, it also formed a strategic partnership with <a href="https://sp-edge.com/updates/19868">BASF </a>to create an animal-free material called Bio-VERA that replicates the look, feel, and aging properties of traditional leather, suede, or chamois.In <a href="https://sp-edge.com/updates/30500">June 2024</a>, the company partnered with Earthletica to unveil the Bronte Jacket which used Bio-Alloy Shield technology.Funding and financialsIn April 2021, the company raised USD 130 million in a Series C funding round led by Key Partners Capital to (i) develop the company's biofabrication technology, used in creating an alternative to fossil-fuel-based textile coatings; and (ii) scale-up and commercialize its collagen-based leather material.

Modern Meadow

Developers of materials with applications across apparel, automobile, home goods, etc.

Developers of non-leather material alternatives such as wool, silk, and viscose—mostly for apparel

Developers of alternatives to plastic and other materials used in packaging

Developers of alternative materials for industrial applications such as sporting goods, electronic components, and automotive parts

Reuses waste to create bio-based materials

Sustainable alternatives to materials like animal leather, silk, plastic

ANALYST_QUICK_TAKE

<div>
 Biotech startup Kelpi, based in the UK, has managed to secure GBP 4.3 million (equivalent to ~USD 5.5 million) in a funding round. Lead investor was Blackfinch Ventures, accompanied by the likes of Green Angel Ventures, Kadmos Capital, QantX, Evenlode Foundation, South West Investment Fund, Bristol Private Equity Club (BPEC), and One Planet Capital. There were also contributions from additional angel investors.
 By securing these funds, Kelpi intends to expand its work team and overall operations. The funds will also aid in conducting large-scale pilot projects and obtaining necessary regulatory approvals. The firm has indicated an intention to launch its unique product, seaweed-based packaging, for commercial purposes by mid-2025.
</div> Analyst QuickTake: 
 Kelpi raised ~USD 3.6 million to scale up the development of its bioplastic in <a href="https: 
//sp-edge.com/updates/16153"> February 2023 </a> . The company has also entered strategic partnerships with L’Oréal, Diageo, and Waitrose, revealing the potential of the company’s solution.

Kelpi

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