Threshold is an early-stage venture capital firm that focuses on a high-conviction investment strategy. The firm partners with entrepreneurs to build innovative consumer, enterprise, and healthcare technology companies.

Threshold

Felicis Ventures is a venture capital firm based in Menlo Park, California. The firm invests in seed through Series C stage companies across multiple sectors and industries reinventing core markets, as well as those creating frontier technologies. Felicis currently manages over $2B in capital across 8 funds. The firm is an early backer of more than 40 companies valued at $1B+. More than 90 of its portfolio companies have been acquired or gone public since the firm was founded by Aydin Senkut in 2006.

Felicis

Torch Capital is a New York-based early-stage venture fund investing in consumer technology companies and the infrastructure layers that power them. Torch invests in visionary founders using technology to revolutionize how consumers and businesses operate.

Torch Capital

City Light is a venture capital firm that invests early in impactful companies. They partner with experienced teams building category-defining solutions in the areas of education, safety and care, and the environment - where more revenue equals better lives at scale, every time. As one of the earliest and most successful impacts investing firms, City Light has a track record of identifying and scaling impact in ways that build better companies.  The firm was founded in 2004 and is based in New York, New York. Some of its key portfolio investments are 2U (Nasdaq: TWOU), ShotSpotter (Nasdaq: SSTI), Trilogy Education, and Ready Responders.

City Light Capital

Human Ventures is a fund and partner in New York City. They possess their own perspective on evaluating companies due to their experience in building businesses themselves. Consequently, Human Ventures focuses on supporting founders who are establishing category-defining companies in the pre-seed and seed stages. In terms of their investment focus, they concentrate on the Human Needs Economy, which encompasses areas such as health and wellness, the future of work and finance, the attention economy, and human connection through experiences.

Human Ventures

Salvo Health

Salvo Health is an app-based specialty care provider focusing on chronic gut conditions. Salvo Health improves access to advanced, specialty healthcare for anyone living with chronic conditions. Salvo Health employs a brand-named form of therapy called Whole Self Science, which takes into account general health and contributing factors outside of the gut, in order to pinpoint the underlying causes and offer individualized and ongoing treatment strategies.

Virtual gastrointestinal (GI) care startup Salvo Health helps patients manage chronic gut illnesses such as irritable bowel syndrome (IBS), celiac disease, gastroesophageal reflux disease (GERD), dyspepsia, and small intestinal bacterial overgrowth (SIBO). The app-based approach provides users with personalized nutrition plans, brain-gut exercises, sleep and stress management, diagnostic testing, and medication.

Membership-based, non-insurance healthcare companies helping maintain a steady state of well being.

Preventive Healthcare

Salvo Health Partners with Pinnacle GI Partners to Revolutionize Wraparound Patient Care

Virtual gastrointestinal (GI) care startup Salvo Health helps patients manage chronic gut illnesses such as irritable bowel syndrome (IBS), celiac disease, gastroesophageal reflux disease (GERD), dyspepsia, and small intestinal bacterial overgrowth (SIBO). The app-based approach provides users with personalized nutrition plans, brain-gut exercises, sleep and stress management, diagnostic testing, and medication.The company operates a B2C model, charging a membership fee USD 127 per month. Users can sign up after an online assessment and they are matched to a care team consisting of a physician, a health coach, and a care navigator. Users are given a customized care plan for 90 days, after which an effective long-term treatment plan is provided. As of August 2022, the company operates in 13 states across the US.Funding and financialsFounded in 2021, the company launched out of stealth in August 2022. In <a href="https://sp-edge.com/updates/27112">February 2024</a>, the company raised USD 5 million in a seed prime funding round. The round was co-led by City Light Capital and Human Ventures. The new funds were allocated towards expanding the enterprise-wide implementation of Salvo's GI care.

Cardiomo Care is developing noninvasive wearable devices to alert users and caretakers when there are abnormalities in the heartbeat. The company’s AI engine, trained on existing and growing data sets, can predict potential heart issues up to two hours before they occur, enabling early detection and intervention for arrhythmias and other cardiovascular diseases (CVDs).The company's product, CardiomoPatch, is a waterproof, wearable patch capable of long-term wear with a 10-day battery life. The patch monitors a patient's cardiac data, including ECG outputs, breathing, and skin temperature, and transmits the data via a mobile app for analysis by Cardiomo's AI engine.&nbsp;As of May 2024, the company is yet to commercialize its product and has over 1,600 pre-orders.

Cardiomo Care

Omada is a prevention-focused digital therapeutics startup that helps members achieve health goals through lifestyle changes. It offers four evidence-based, virtual prevention programs for managing hypertension, musculoskeletal (MSK) issues, prediabetes, and diabetes.Omada offers real-time data tracking through connected devices (such as wireless scales, blood pressure, and glucose monitors) and access to personalized coaching sessions via a mobile app as part of its prevention program. It also provides an online community of peers with similar health conditions to discuss challenges and provide support. In May 2021, Omada became the first fully-virtual healthcare provider to earn the National Committee for Quality Assurance’s Population Health Program Accreditation for its type 2 diabetes and type 2 diabetes + hypertension programs.Unlike its peers, Omada operates a performance-based business model where it charges clients an enrollment fee based on the number of users and a performance fee based on how much weight their employees lose. In May 2020, the company acquired virtual physical therapy startup Physera.Key customers and partnershipsAs of May 2024, Omada had more than 1 million members from more than 1,900 enterprise clients across all 50 US states. Its B2B employer and health plan client base include key clients such as American Eagle, Kaiser Permanente, Costco Wholesale, 3M, and Marvin. Additionally, the company has partnered with health systems and hospitals such as Intermountain Healthcare to provide its preventive programs as a covered benefit.In <a href="https://sp-edge.com/updates/15587">January 2023</a>, the company partnered with health service company Castell (a subsidiary of Intermountain Healthcare) to provide its diabetes programs to members from Intermountain Healthcare’s primary care providers in its Utah Medical Group. Further in <a href="https://sp-edge.com/updates/25245">January 2024</a>, the company partnered with Amazon to expand access to its cardiometabolic program.

Omada Health

VillageMD provides primary care services for patients. It also provides tools, technology, and staffing support needed for physicians to deliver high-quality services. VillageMD’s service delivery methods include traditional freestanding clinics, Village Medical at Walgreens co-located clinics, as well as at-home and around-the-clock virtual visits. It also leverages a team-based approach to care where physicians lead nurse practitioners, pharmacists, mental health specialists, and dietitians to offer a holistic care program. The technology of VillageMD includes docOS, an operating system that enables better patient care by connecting various clinical source systems with ongoing patient-generated data coupled with an AI engine to continuously analyze messages to enable patient self-care.The company made several acquisitions to expand its footprint: 1) <a href="https://sp-edge.com/updates/14347">Summit Health</a> for USD 8.9 billion in November 2022, 2) Healthy Interactions, an interactive patient education platform, in February 2022, and 3) <a href="https://sp-edge.com/updates/16968">Starling Physicians</a>, a primary care and specialty care provider, in March 2023.Key customers and partnershipsIn June 2020, VillageMD and Walgreens Boots Alliance announced a collaborative effort to open at least 600 Village Medical centers at Walgreens across more than 30 US markets by 2025. Walgreens invested USD 5.2 billion in VillageMD (from the previously announced USD 1.0 billion), raising its ownership stake to 63% (from 30%).However, as of May 2024, Walgreens had plans to close 160 VillageMD clinics as part of a cost-cutting plan.

VillageMD

Cityblock Health is a value-based healthcare provider focused on delivering comprehensive care to underserved communities, primarily Medicaid and lower-income Medicare beneficiaries. The company combines primary care, behavioral health, and social services to address the complex physical, mental, and social needs of its members.Cityblock's model involves partnering with local community-based organizations and deploying multidisciplinary care teams that include doctors, nurses, behavioral health specialists, and community health workers. These teams provide personalized care through 24/7 access to multi-modal care delivery, including in-home visits, telehealth, and community health hubs.The services of Cityblock are available to members at no additional cost if they are covered by an eligible health plan.Key Customers and PartnershipsAs of May 2024, the company’s services were available in seven states across the US and served over 100,000 members.In May 2024, it partnered with <a href="https://sp-edge.com/updates/29647">Sunshine Health</a> to expand to Florida, and, in <a href="https://sp-edge.com/updates/13270">September 2022</a>, it partnered with MDwise to expand into Indiana. Prior to that, the company had partnered with insurance providers such as ConnectiCare (Connecticut), Tufts Health Plan (Massachusetts), Emblem Health (New York), Healthy Blue (North Carolina), Molina Healthcare (Ohio) and CareFirst (Washington DC).Funding and FinancialsCityblock is a spin-off of Sidewalk Labs, an Alphabet company that incubates and invests in tech companies and products to improve urban infrastructure. It completed a USD 400 million Series D funding round led by Softbank in <a href="https://sp-edge.com/updates/5326">September 2021</a>, valuing the company at USD 5.7 billion. The funds were used to expand its services.

Cityblock Health

Everside Health (formerly Paladina Health) offers preventative care for chronic conditions and primary, mental and occupational healthcare treatments for acute conditions. Patients benefit from around-the-clock access to care, same-day or next-day appointments for in-person, and virtual care visits with zero copays.Everside aims to generate around 17% healthcare cost savings in three years and 31% in five years for its corporate members by leveraging a data-driven approach to care coordination.The company leverages data from past medical records, predictive analytics, and AI in the delivery of preventative care services.Founded in 2010 under the name Paladina Health, the company was rebranded in November 2020 as Everside Health following a merger between three primary care groups (Paladina, Activate Healthcare, and Healthstat). Furthermore, in February 2024, Everside Health merged with primary care provider Marathon Health to form a combined entity that would operate as Marathon Health, and, as of May 2024, the integration was ongoing.Key customers and partnershipPost-merger with Marathon Health, the combined entity would serve 2.5 million patients through over 680 clinics across 41 states.Funding and financialsThe company received its most recent investment in July 2022, amounting to USD 164 million in growth equity funding. The round was led by New Enterprise Associates (NEA). The funds were allocated toward growing its market presence and exploring opportunities for M&amp;A as well as to enhance and improve its product features. Additionally, the firm planned to expand its coverage of specialty care services aimed at individuals, employers, and union organizations.

Everside Health

Platforms offer a subscription-based or B2B-sponsored, evidence-based program for managing a specific long-term health condition.

DPCs offer value-based primary and preventive care services addressing whole-person (social, mental, physical) needs for a fixed monthly or annual fee paid by either the patient, insurance provider, or employer.

Companies offer B2B and D2C evidence-based treatments delivered via software programs to prevent and manage a variety of chronic conditions.

Tools that collect and analyze real-time patient data that supports healthcare providers with clinical decisions,  improves patient outcomes, and reduces medical errors.

Companies offer independent physician practices and hospitals with the tools (patient engagement, care coordination, administrative services) to help manage and improve clinical health outcomes of a defined group of individuals or large populations.

Platforms are used to track and gather patient health-related information via either a connected device or at-home test kits to detect the early onset of disease and identify any abnormalities in readings—but do not include a treatment plan.

To gather large amounts of real-time data for chronic care management, DTx, and patient monitoring

XR used by some startups for chronic pain management

Offers digital means of providing direct primary care, passive remote monitoring, chronic care management, etc.

AI/ML is used in predictive analytics, diagnostics tools, and population management

Offers tailored preventive interventions and treatments to the specific needs and characteristics of each individual

ANALYST_QUICK_TAKE

<div>
 New York's virtual gastrointestinal care startup, Salvo Health, has raised $5 million in a seed prime funding round. Co-leaders of the round included City Light Capital and Human Ventures. Other participants included Threshold Ventures, Torch Capital, Felicis Ventures, and Anmol Madan. As part of the deal, Rachel Parlier from City Light and Emily Melton from Threshold are set to join the company's board of directors alongside Salvo's founder and CEO, Jeffrey Glueck.
 Salvo Health intends to use the new funding to broaden its implementation of GI care across a number of healthcare providers. This will include gastroenterology private practices, health systems and accountable care organizations.&nbsp;
</div> Analyst QuickTake: 
 In the past year, startups focused on chronic disease management, particularly those specializing in GI conditions, have been attracting funding from investors. For example, <a href="https: 
//sp-edge.com/updates/22063"> Vivante Health </a> raised USD 31 million in a Series B funding round in September 2023, and <a href="https: 
//sp-edge.com/updates/17653"> Oshi Health </a> raised USD 30 million in a Series B funding in April 2023.

Salvo Health

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