Ember LifeSciences

Ember’s proprietary cold chain technology is revolutionizing the transportation of life-saving medicines around the world within the healthcare industry. With a mission to save lives, improve patient outcomes, and reduce waste, the Ember Cube is the world's first self-refrigerated cloud-based shipping box.

Ember is a technology company that has developed innovative solutions for cold chain logistics in the healthcare industry. The company's flagship product is the Ember Cube, a self-refrigerated, cloud-based shipping container designed to transport temperature-sensitive pharmaceuticals. Launched in partnership with Cardinal Health in 2022, the Ember Cube aims to reduce shipping waste by replacing single-use materials like Styrofoam and ice packs. Each Cube is equipped with cellular radio, GPS, and sensors to provide real-time location, temperature, and humidity tracking. The company's technology helps ensure the safe and efficient transport of vaccines, biologics, and cell and gene therapies.

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Making cold chains faster, smarter, and cooler.

Cold Chain Innovation

Ember

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Ember is a technology company that has developed innovative solutions for cold chain logistics in the healthcare industry. The company's flagship product is the Ember Cube, a self-refrigerated, cloud-based shipping container designed to transport temperature-sensitive pharmaceuticals. Launched in partnership with Cardinal Health in 2022, the Ember Cube aims to reduce shipping waste by replacing single-use materials like Styrofoam and ice packs. Each Cube is equipped with cellular radio, GPS, and sensors to provide real-time location, temperature, and humidity tracking. The company's technology helps ensure the safe and efficient transport of vaccines, biologics, and cell and gene therapies.
In August 2022, Ember announced the spinout of its healthcare vertical into a new company called Ember LifeSciences. This division is focused on expanding Ember's temperature control technologies specifically for pharmaceutical cold chain applications. Ember LifeSciences is developing additional shipping prototypes, including an ultra-low temperature shipper and a cryogenic shipper for cell and gene therapy products. The company secured an initial investment from Cardinal Health to support the development of these new cold chain solutions.
Key customers and partnerships
Ember has established a key partnership with Cardinal Health, a major healthcare distributor, to bring the Ember Cube to market. This collaboration aims to revolutionize pharmaceutical cold chain shipping and reduce waste in the industry.

Transparent Path is a logistics technology company that provides real-time, end-to-end shipment visibility solutions to reduce costs, risks, and environmental impact in supply chains. The company's platform utilizes advanced technologies including 5G, IoT, AI, and cloud computing to monitor shipments continuously. Transparent Path's system tracks various parameters such as location, temperature, humidity, tilt, shock, acceleration, light exposure, and door openings. This comprehensive monitoring helps ensure product quality and freshness, particularly for perishable goods in industries like food and beverage, pharmaceuticals, biomedical products, sensitive chemicals, and high-value assets.
The company's platform is designed to facilitate collaboration and seamless handoffs throughout the supply chain, tracking changes in custody without requiring additional infrastructure. Transparent Path offers a unique, patent-pending freshness prediction metric called FreshScore, which uses proprietary machine-learning algorithms. The system aims to prevent lost loads, provide evidence for meeting service-level agreements, and help businesses reclaim costs lost to supply chain inefficiencies. Transparent Path's flexible pricing model allows customers to use and reuse trackers as needed, paying only for the trackers they require on a monthly basis.
Key customers and partnerships
Transparent Path has worked with Feeding America, a nationwide network of food banks. Rod Wieber noted that the company's technology has been added to loads shipped across the nation to food banks in the Feeding America network over the past year. The ability to track load location and monitor temperature has provided assurance that food arrives in optimal condition for quick distribution to those in need. Wieber stated that Transparent Path's sensors have exceeded expectations in terms of performance and reliability.

Transparent Path

Modality Solutions, founded in 2011, is a leading biopharmaceutical cold chain engineering firm specializing in the validation, optimization, and regulatory approval of temperature-sensitive therapies. The company focuses on integrating cold chain operations, developing transport validation strategies, and supporting global regulatory applications for biopharmaceutical products. Modality Solutions' core offering is its unique Advantage Transport Simulation Laboratory in Bloomington, Indiana, which operates under an ISO 9001:2015 certified quality system. This lab is the only one of its kind that concurrently tests across five hazards that can impact drugs during transport: temperature, vibration, shock, pressure, and humidity.
The company's services include engineering consulting, systems integration, and simulation laboratory testing from drug discovery through distribution. Modality Solutions employs a team of chemical, biomedical, and mechanical engineers with expertise in cold chain management, package engineering, and regulatory compliance. Their approach combines best practices in process validation, systems qualification, and risk assessment to ensure product quality and patient safety. In 2021, Modality Solutions reported a 64% growth rate and was ranked No. 179 on the Inc. 5000 Regionals: Texas list. The company has also been recognized on Inc. Magazine's national list of fastest-growing private companies for three consecutive years, with a reported revenue growth of 120% between 2015 and 2018.
Key customers and partnerships
Modality Solutions serves a diverse range of clients in the biopharmaceutical industry, including emerging biopharmaceuticals, pharmaceutical manufacturers, cell and gene therapy developers, and companies working on drug-device combination products. Some of their notable clients include Teva, Immunomedics, Atara Bio, CSL Plasma, Abbott Vascular, and Regeneron. The company also works with public health organizations, assisting in the deployment of vaccines and therapeutics. Additionally, Modality Solutions collaborates with regulatory consultants and biopharmaceutical investors to provide cold chain validation services and strengthen due diligence processes for portfolio businesses.

Modality Solutions

Moffett Automation specializes in automated pallet storage solutions, with their flagship product being the Moffett Taxi System. The company's technology focuses on maximizing storage capacity in warehouses, allowing businesses to store more pallets per square meter than other automated storage solutions available globally. Moffett Automation's system is designed to utilize warehouse space efficiently, from floor to roof, enabling companies to scale their storage capabilities. The company combines innovative technology with seven decades of experience in the field to develop their solutions. Their automated storage system aims to streamline various aspects of warehousing operations, potentially leading to increased profits and operational efficiency for their clients.

Moffett Automated Solutions

NewCold is a global leader in advanced food logistics, specializing in automated cold storage and distribution solutions. The company operates state-of-the-art automated warehouses across Europe, Australia, and North America, with a total capacity of over 1.3 million pallet positions as of 2024. NewCold's facilities utilize proprietary software and technology to ensure food safety and quality while being approximately 50% more energy-efficient than traditional cold stores. The company's automated systems enable high-volume storage and retrieval, with some facilities capable of handling over 11,000 pallet movements per day.
NewCold's warehouses feature vertical layouts optimized for pallet storage, with some facilities standing over 14 stories tall. The company's technology includes automated pallet handling systems, unmanned stacker cranes, conveyors, and automated truck unloading systems. NewCold's proprietary warehouse management software and control systems are developed in-house, allowing for seamless integration with customers' ERP systems. The company also offers transportation services, utilizing a fleet of over 200 trucks and 500 trailers as part of its end-to-end supply chain solutions.
In recent years, NewCold has significantly expanded its presence in North America. In October 2023, the company opened a USD 300 million facility in Lebanon, Indiana, which is set to be one of the largest and most advanced cold storage facilities in the world. NewCold also operates facilities in Tacoma, Washington, and Burley, Idaho. The company has announced plans to add 25 more facilities in North America by 2030 to meet growing demand.

NewCold

CryoLogistics offers SnowSHIP technology for shipping perishable goods with precise temperature control from source to destination. The company's solution incorporates embedded IoT connectivity to ensure the safety, security, and traceability of goods throughout the supply chain. SnowSHIP utilizes one of nature's most abundant natural refrigerants, which helps lower a company's carbon footprint and positions users as climate-friendly service providers. This technology aims to provide an innovative approach to temperature-controlled logistics, addressing the needs of businesses dealing with perishable items.

CryoLogistics

Companies providing cold chain storage solutions, such as refrigerated facilities and warehouses for the secure storage of temperature-sensitive goods

Companies offering technologies to track and maintain precise temperature conditions throughout the entire supply chain, such as IoT sensors and temperature monitoring devices

Companies that design and produce packaging solutions to safeguard the integrity of temperature-sensitive products during transport

Companies that facilitate the safe and controlled movement of temperature-sensitive goods from one location to another, employing specialized equipment and logistics

Companies that provide technology-driven solutions to optimize and manage parts or all of the cold chain process

Virtual cold chain models are developed to assess the efficiency and efficacy of cold chain alternatives.

Temperature monitoring solutions include IoT sensors for monitoring products during transportation and storage.

Cold chain innovations provide real-time monitoring into the condition of products during transit.

AI/ML aid cold chain optimization by utilizing modeling capabilities in selecting the best cold chain alternatives.

Blockchain-based cold chain solutions enables supply chain transparency,  food safety, and cold chain compliance.

Certain packaging solutions contribute towards a circular economy by creating insulated packaging using repurposed materials.

Cold chain innovations improve the performance of cold chains and thus reduce waste, thus contributing to sustainability.

Ember

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