AXA Investment Managers is an active, global, multi-asset investor focused on enabling more people to harness the power of investing to meet their financial goals. As the investment partner of AXA Group, the A-rated protection and wealth management provider, AXA Investment Managers draws on a longstanding heritage of creating solutions to manage real-life risks and challenges. At the same time, AXA Investment Managers' investment professionals are committed to finding efficient and sustainable sources of return across world markets, from equities to fixed income, and real assets to other alternative asset classes.

AXA Investment Managers

Cross-Border Impact Ventures invests in health technology companies that address the needs of women, children, and adolescents. It has partnered with Grand Challenges Canada to develop a  platform that breaks the paradigm of who benefits from leading technologies.  The firm was founded in 2019 and is based in Toronto, Canada.

Cross-Border Impact Ventures

KOFA Healthcare Investments is a healthcare investment firm investing in med tech companies primarily, but not exclusively, in orthopedic, cardiovascular and women's health opportunities.

KOFA Healthcare

Avestria Ventures is an investment firm that focuses on women's health and female-led life science and healthcare companies. They define women's health as illnesses that affect women exclusively (such as menopause), differently (such as cardiovascular disease), or disproportionately (such as Alzheimer's).

Avestria Ventures

Axena Health

Axena Health is a women-led company dedicated to improving the lives of women with pelvic floor disorders by leveraging the power of digital technology. The company's devices specialize in women’s pelvic health and help them endure the medical and social effects of incontinence. Its product, Leva Pelvic Health System, is a prescription digital therapeutic (PDT) that offers at-home treatment for urinary incontinence (UI) and chronic fecal incontinence (FI) in women.

Axena Health is a women-led medical device company offering treatment solutions for women with pelvic floor disorders. Its flagship product, the Leva Pelvic Health System, offers a non-invasive, and medication-free treatment for urinary incontinence (UI) and chronic fecal incontinence (FI) in women. The Leva System is a prescription digital therapeutic that guides women through pelvic floor muscle training (PFMT) at home using a small FDA-cleared vaginal motion sensor connected to a smartphone app. An 8-week clinical study led to fewer leaking episodes and symptom improvement.&nbsp;

Membership-based, non-insurance healthcare companies helping maintain a steady state of well being.

Preventive Healthcare

Axena Health, UpScriptHealth partner on telehealth service for women

Axena Health is a women-led chronic care management startup offering treatment solutions for women with pelvic floor disorders. The company’s flagship product, the Leva Pelvic Health System, is a prescription digital therapeutic (PDT) that offers at-home treatment for urinary incontinence (UI) and chronic fecal incontinence (FI).The Leva Pelvic Health System uses wireless connected motion sensor technology. It claims to be the only pelvic floor muscle training device that combines a small vaginal motion sensor with a smartphone app focused on strengthening pelvic floor muscles. The FDA cleared, non-invasive system allows users to monitor progress of pelvic floor muscle training, providing them with coaching as they progress. Additionally, the app tracks progress over time and shares this information with both the user and their healthcare provider.Founded in January 2023, the company operates a B2B2C business model by partnering with healthcare providers. Axena obtained the system from Renovia, which created and sold the Leva system before its closure in 2022. An eight-week clinical study led to fewer leaking episodes and symptom improvement.Funding and financials<a href="https://sp-edge.com/updates/16513">In February 2023 </a>, the company raised USD 25 million in a Series A funding round led by AXA IM Alts through its Global Healthcare Private Equity Strategy. The funds were used to support the expansion of and patient access to the Leva Pelvic Health System.

Axena Health is a women-led medical device company offering treatment solutions for women with pelvic floor disorders. Its flagship product, the Leva Pelvic Health System, offers a non-invasive, and medication-free treatment for urinary incontinence (UI) and chronic fecal incontinence (FI) in women. The Leva System is a prescription digital therapeutic that guides women through pelvic floor muscle training (PFMT) at home using a small FDA-cleared vaginal motion sensor connected to a smartphone app. An 8-week clinical study led to fewer leaking episodes and symptom improvement.&nbsp;Further, the system allows users to monitor progress of PFMT, providing them with coaching as they progress. Additionally, the app tracks progress over time and shares this information with both the user and their healthcare provider.&nbsp;Axena obtained the system from Renovia, which created and sold the Leva system before its closure in 2022.&nbsp;Key customers and partnershipsThe company operates a B2B2C business model offering solutions via insurance providers, namely Cigna healthcare (March 2023), Highmark Blue Cross Blue Shield (April 2024), and Blue Cross Blue Shield of North Dakota (April 2024).Further in <a href="https://sp-edge.com/updates/32110">July 2024</a>, Axena Health partnered with UpScriptHealth to offer telehealth services for incontinence treatment.

Cardiomo Care is developing noninvasive wearable devices to alert users and caretakers when there are abnormalities in the heartbeat. The company’s AI engine, trained on existing and growing data sets, can predict potential heart issues up to two hours before they occur, enabling early detection and intervention for arrhythmias and other cardiovascular diseases (CVDs).The company's product, CardiomoPatch, is a waterproof, wearable patch capable of long-term wear with a 10-day battery life. The patch monitors a patient's cardiac data, including ECG outputs, breathing, and skin temperature, and transmits the data via a mobile app for analysis by Cardiomo's AI engine.&nbsp;As of May 2024, the company is yet to commercialize its product and has over 1,600 pre-orders.

Cardiomo Care

Omada is a prevention-focused digital therapeutics startup that helps members achieve health goals through lifestyle changes. It offers four evidence-based, virtual prevention programs for managing hypertension, musculoskeletal (MSK) issues, prediabetes, and diabetes.Omada offers real-time data tracking through connected devices (such as wireless scales, blood pressure, and glucose monitors) and access to personalized coaching sessions via a mobile app as part of its prevention program. It also provides an online community of peers with similar health conditions to discuss challenges and provide support. In May 2021, Omada became the first fully-virtual healthcare provider to earn the National Committee for Quality Assurance’s Population Health Program Accreditation for its type 2 diabetes and type 2 diabetes + hypertension programs.Unlike its peers, Omada operates a performance-based business model where it charges clients an enrollment fee based on the number of users and a performance fee based on how much weight their employees lose. In May 2020, the company acquired virtual physical therapy startup Physera.Key customers and partnershipsAs of May 2024, Omada had more than 1 million members from more than 1,900 enterprise clients across all 50 US states. Its B2B employer and health plan client base include key clients such as American Eagle, Kaiser Permanente, Costco Wholesale, 3M, and Marvin. Additionally, the company has partnered with health systems and hospitals such as Intermountain Healthcare to provide its preventive programs as a covered benefit.In <a href="https://sp-edge.com/updates/15587">January 2023</a>, the company partnered with health service company Castell (a subsidiary of Intermountain Healthcare) to provide its diabetes programs to members from Intermountain Healthcare’s primary care providers in its Utah Medical Group. Further in <a href="https://sp-edge.com/updates/25245">January 2024</a>, the company partnered with Amazon to expand access to its cardiometabolic program.

Omada Health

VillageMD provides primary care services for patients. It also provides tools, technology, and staffing support needed for physicians to deliver high-quality services. VillageMD’s service delivery methods include traditional freestanding clinics, Village Medical at Walgreens co-located clinics, as well as at-home and around-the-clock virtual visits. It also leverages a team-based approach to care where physicians lead nurse practitioners, pharmacists, mental health specialists, and dietitians to offer a holistic care program. The technology of VillageMD includes docOS, an operating system that enables better patient care by connecting various clinical source systems with ongoing patient-generated data coupled with an AI engine to continuously analyze messages to enable patient self-care.The company made several acquisitions to expand its footprint: 1) <a href="https://sp-edge.com/updates/14347">Summit Health</a> for USD 8.9 billion in November 2022, 2) Healthy Interactions, an interactive patient education platform, in February 2022, and 3) <a href="https://sp-edge.com/updates/16968">Starling Physicians</a>, a primary care and specialty care provider, in March 2023.Key customers and partnershipsIn June 2020, VillageMD and Walgreens Boots Alliance announced a collaborative effort to open at least 600 Village Medical centers at Walgreens across more than 30 US markets by 2025. Walgreens invested USD 5.2 billion in VillageMD (from the previously announced USD 1.0 billion), raising its ownership stake to 63% (from 30%).However, as of May 2024, Walgreens had plans to close 160 VillageMD clinics as part of a cost-cutting plan.

VillageMD

Cityblock Health is a value-based healthcare provider focused on delivering comprehensive care to underserved communities, primarily Medicaid and lower-income Medicare beneficiaries. The company combines primary care, behavioral health, and social services to address the complex physical, mental, and social needs of its members.Cityblock's model involves partnering with local community-based organizations and deploying multidisciplinary care teams that include doctors, nurses, behavioral health specialists, and community health workers. These teams provide personalized care through 24/7 access to multi-modal care delivery, including in-home visits, telehealth, and community health hubs.The services of Cityblock are available to members at no additional cost if they are covered by an eligible health plan.Key Customers and PartnershipsAs of May 2024, the company’s services were available in seven states across the US and served over 100,000 members.In May 2024, it partnered with <a href="https://sp-edge.com/updates/29647">Sunshine Health</a> to expand to Florida, and, in <a href="https://sp-edge.com/updates/13270">September 2022</a>, it partnered with MDwise to expand into Indiana. Prior to that, the company had partnered with insurance providers such as ConnectiCare (Connecticut), Tufts Health Plan (Massachusetts), Emblem Health (New York), Healthy Blue (North Carolina), Molina Healthcare (Ohio) and CareFirst (Washington DC).Funding and FinancialsCityblock is a spin-off of Sidewalk Labs, an Alphabet company that incubates and invests in tech companies and products to improve urban infrastructure. It completed a USD 400 million Series D funding round led by Softbank in <a href="https://sp-edge.com/updates/5326">September 2021</a>, valuing the company at USD 5.7 billion. The funds were used to expand its services.

Cityblock Health

Everside Health (formerly Paladina Health) offers preventative care for chronic conditions and primary, mental and occupational healthcare treatments for acute conditions. Patients benefit from around-the-clock access to care, same-day or next-day appointments for in-person, and virtual care visits with zero copays.Everside aims to generate around 17% healthcare cost savings in three years and 31% in five years for its corporate members by leveraging a data-driven approach to care coordination.The company leverages data from past medical records, predictive analytics, and AI in the delivery of preventative care services.Founded in 2010 under the name Paladina Health, the company was rebranded in November 2020 as Everside Health following a merger between three primary care groups (Paladina, Activate Healthcare, and Healthstat). Furthermore, in February 2024, Everside Health merged with primary care provider Marathon Health to form a combined entity that would operate as Marathon Health, and, as of May 2024, the integration was ongoing.Key customers and partnershipPost-merger with Marathon Health, the combined entity would serve 2.5 million patients through over 680 clinics across 41 states.Funding and financialsThe company received its most recent investment in July 2022, amounting to USD 164 million in growth equity funding. The round was led by New Enterprise Associates (NEA). The funds were allocated toward growing its market presence and exploring opportunities for M&amp;A as well as to enhance and improve its product features. Additionally, the firm planned to expand its coverage of specialty care services aimed at individuals, employers, and union organizations.

Everside Health

Platforms offer a subscription-based or B2B-sponsored, evidence-based program for managing a specific long-term health condition.

DPCs offer value-based primary and preventive care services addressing whole-person (social, mental, physical) needs for a fixed monthly or annual fee paid by either the patient, insurance provider, or employer.

Companies offer B2B and D2C evidence-based treatments delivered via software programs to prevent and manage a variety of chronic conditions.

Tools that collect and analyze real-time patient data that supports healthcare providers with clinical decisions,  improves patient outcomes, and reduces medical errors.

Companies offer independent physician practices and hospitals with the tools (patient engagement, care coordination, administrative services) to help manage and improve clinical health outcomes of a defined group of individuals or large populations.

Platforms are used to track and gather patient health-related information via either a connected device or at-home test kits to detect the early onset of disease and identify any abnormalities in readings—but do not include a treatment plan.

To gather large amounts of real-time data for chronic care management, DTx, and patient monitoring

XR used by some startups for chronic pain management

Offers digital means of providing direct primary care, passive remote monitoring, chronic care management, etc.

AI/ML is used in predictive analytics, diagnostics tools, and population management

Offers tailored preventive interventions and treatments to the specific needs and characteristics of each individual

ANALYST_QUICK_TAKE

PROMINENT_CATEGORY

<div>
 Axena Health, a company targeting women's pelvic health, teamed up with telemedicine platform UpScriptHealth. The partnership is set to provide telehealth services to women seeking help for urinary incontinence.
 Thanks to this collaboration, women can get access to Axena's FDA-approved Leva System through online consultations with UpScriptHealth providers. The process involves completing a questionnaire, having a virtual consultation, and receiving a prescription for the Leva System if deemed suitable. The goal of this collaboration is to increase access to first-line incontinence treatment, especially with the rising shortage of OB-GYNs in the US. The treatment strategy involves pelvic floor muscle training to handle urinary incontinence from home, eliminating the need for medications or surgery.
 
</div> Analyst QuickTake: 
 The partnership helps expand Axena Health's offerings, particularly in telehealth. The company has been focused on expanding its offerings and has also raised funding for this purpose in <a href="https: 
//sp-edge.com/updates/30127"> June 2024 </a> .

Axena Health

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