Agilent Ventures

Leveraging personal data for custom-fit diagnosis and treatment

Precision Medicine

Mission Bio is a biotechnology company that specializes in developing and commercializing single-cell multi-omics solutions for precision medicine. The company's flagship product, the Tapestri Platform, is a single-cell genomics and proteogenomic characterization tool that allows researchers and clinicians to have a deeper knowledge of disease profiles by identifying disease subtypes, predicting disease progression, and understanding treatment response, and thereby accelerating discovery, development, and delivery of precision medicine. The platform also facilitates product characterization in cell therapeutics.Furthermore, the company claims that the platform's latest version launched in May 2023 captures 4x the number of cells compared to the previous chemistry. In addition, Tapestri is the only commercialized multi-omics platform capable of analyzing DNA and protein simultaneously from the same sample at single-cell resolution. It is being used by customers at research centers, pharmaceutical, and diagnostics companies to develop treatments, and, eventually, as cures for cancer.Key Customers and PartnershipsThe company has several key partnerships with pharma and biopharma companies including Amgen, Merck, Abbvie, and CRISPR Therapeutics.The company partnered with clinical diagnostic company <a href="https://sp-edge.com/updates/17651">Fulgent Genetics </a>(April 2023) to expand the accessibility of single-cell multiomics for drug development and clinical research, single-cell bioinformatics company Abiosciences (in December 2022) to co-develop bioinformatics packages for translational and clinical research applications in hematological cancers, laboratory automation solution company S2 Genomics (April 2022) to offer a single streamlined workflow for solid tumor applications from sample prep through analysis, and single-cell omics technology company SequMed (December 2021) to expand its product and services offerings into China.

Tagomics transform disease diagnosis through comprehensive multitopic profiling.

NanoCellect Biomedical develops and delivers microfluidic-based solutions that are affordable, compact, and easy to use. Its expanding portfolio of instruments and consumables enables biomedical scientists to analyze and sort cells required for drug discovery, single cell-omics, cloning, antibody discovery, and basic research.

Mission Bio delivers targeted solutions for high-impact applications with the Tapestri Platform. The Tapestri Platform is the industry’s first and only single-cell multi-omics platform, enabling genotype and phenotype from the same cell and precise detection of heterogeneity in disease progression and treatment response. Application areas include oncology blood cancers, solid tumors, and genome editing validation.

ForteBio is a venture-capital funded life science company developing analytical systems to provide rapid, real-time results for protein quantification or characterization of protein-protein interaction. These systems enable real-time analysis of biomolecular interactions in micro-volume sample sizes, providing information on affinity, kinetics, and concentration.

TelASIC Communications, Inc. develops remote radio head products for WCDMA/HSDPA and WiMAX/LTE infrastructure applications. The company's products enable the transmission of high output power to deliver high data rates and coverage for mobile TV/video/audio/data-centric 3G data services. TelASIC Communications, Inc. was founded in 2001 and is based in El Segundo, California.

Pintail Technologies, Inc. develops real-time adaptive test technology for semiconductor manufacturing companies. The company offers SwifTest, an on-line adaptive test modules that run directly on the automated test equipment (ATE), and capture and analyze data in real-time; and TestScape, an optional database system, which accepts data in real-time from SwifTest and supports various data management applications. Its solutions include TestScape-Charzilla that performs device characterization; TestScape-Aware, which provides a common dashboard for test results across multiple brands of testers and multiple test floors or subcons for issue identification and resolution; and TestScape-OPS that is used for on-line management of test floor and supports real-time overall equipment effectiveness (OEE) and life cycle management functions. The company's solutions also comprise TestVision, which is used to analyze test data and apply sophisticated statistical process control techniques to their test processes; SwifTest-TTO that performs real-time statistical sampling to achieve significant reductions in test time; and SwifTest-MAX, which offers the user a variety of user programmable triggers and alerts that are used to perform complex monitoring and binning analysis on-the-fly. It also provides professional services, such as test engineering, software customization, and training services. The company serves integrated device manufacturers, fabless, test and assembly, and automated test equipment manufacturing companies. It sells its products in the United States, Japan, Singapore, Malaysia, the Philippines, Taiwan, China, Korea, and Europe. Pintail Technologies has strategic alliances with Teradyne Inc. and Salland Engineering.

Infinera Corporation provides optical networking systems based on photonic integration technology in the United States. Its digital transport node (DTN) system utilizes the photonic integrated circuit (PIC) technology to enable digital processing and management of data It can generate wavelength division multiplexing wavelengths and add, drop, switch, manage, protect, and restore network traffic digitally. The company's PICs transmit and receive 100 Gigabits per second of optical capacity and incorporate the functionality of approximately 60 discrete optical components into a pair of indium phosphide chips. The DTN System is used to enable optical to electrical to optical conversions at every network access point to provide communications service providers with the ability to digitally process the information being transported across their optical networks. It also offers a range of support offerings, including 24/7/365 hardware and software technical support, installation and deployment services, spares management, first-line maintenance services, on-site technical services, professional services, product technical training, and extended product warranties. The company offers its products to operators of optical networks, including telecom carriers, cable operators, and Internet or content service providers.  Infinera Corporation, formerly known as Zepton Networks, was founded in 2000 and is headquartered in Sunnyvale, California.

Aria Biosystems is a venture-capital funded life science company developing analytical systems to provide rapid, real-time results for protein quantification or characterization of protein-protein interaction. These systems enable real-time analysis of biomolecular interactions in micro-volume sample sizes, providing information on affinity, kinetics and concentration.  Aria utilizes proprietary bio-layer interferometry (BLI) that enables self-calibration and measurement of molecular interactions using simple-to-use and inexpensive instrumentation. The entire analysis can be completed within minutes and does not require labeling of either probe or target. Aria's analytical capabilities provide greater value in applications where existing methods such as HPLC, ELISA and surface plasmon resonance (SPR) have limitations in throughput, performance and cost.

MEMX is an online platform dedicated to providing educational material on MEMS technology, an emerging technology, which uses the tools and techniques that were developed for the integrated circuit industry. It is based in Palo Alto, California.

Put simply, Agilent Ventures invests in private early-stage high-technology companies. The organization focuses on investments in life sciences (instruments, genomics, and proteomics), wireless (WLAN components and test, embedded measurement, and mobile appliance RF components), and wireline/optical communications (high-speed integrated circuits, packaging and manufacturing technology, and optical components). The firm has active investments in Acer Technology Ventures Asia Pacific, AXSUN Technologies, Infinera, OEwaves, SiRiFIC Wireless, TelASIC Communications, and Tropian. Agilent Ventures is a unit of Agilent Technologies.

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