Elanco

At Athian, we are technology experts with farming in our genes.  We enable environmental sustainability for animal agriculture because we believe in being good stewards of the economic and environmental health of farms and the communities surrounding them.  We use software to aggregate, certify, and fund greenhouse gas reduction plans throughout the entire livestock value-chain.    Athian’s key mission is to help the beef and dairy value chains capture and claim carbon credits earned through sustainability efforts by aggregating, verifying, and certifying greenhouse gas (GHG) reductions, and monetizing those reductions for the producer through the sale of carbon insetting credits.  Athian’s platform is an industry-based analytics tool that provides quality greenhouse gas credits that fund livestock producers’ sustainability measures. Athian is a High Alpha Innovation company based in Indianapolis, Indiana, and is funded by industry leaders Elanco Aniimal Health, DSM-Firmenich, Newtrient LLC., Tyson Ventures, and California Dairies (CDI).  Learn how to join us in this effort at www.athian.ag

Stonehaven Incubate looks at disruptive technologies in human health and identifies the unique opportunities for animals.

Resilient Biotics utilizes big data analytics to design microbiome-based therapeutics and advanced screening methods for prevention and treatment of deadly infectious diseases, with an initial focus on combating respiratory diseases in livestock animals. Resilient’s goal is to provide more effective treatment strategies while reducing the livestock industry’s current dependency on antibiotics.

Boragen develops synthetic chemistry platforms designed to produce next-generation fungicides. The platform supports sustainable farming methods by creating a compound that decreases the probability of fungicide resistance and reduces the amount of chemical applied while maintaining performance and efficacy. The company utilizes boron’s unique properties to design and develop novel solutions targeting needs in crop protection, animal health, and human health. Founded in 2015, Boragen is based in Durham, North Carolina.

Elanco is a global animal health company that benefits people as well as animals through their vision: food and companionship enriching life.

<div> Elanco Animal Health Incorporated (NYSE: ELAN) is a global leader in animal health dedicated to innovating and delivering products and services to prevent and treat disease in farm animals and pets. Founded in 1954 as part of Eli Lilly and Company, Elanco became an independent public company in 2018. The company develops, manufactures and markets health products for pets and farm animals, including vaccines, parasiticides, antibiotics, dermatology treatments, pain medications, and feed additives. Elanco operates in over 90 countries and had revenue of USD 4.42 billion in 2023. Elanco's business is divided into two main segments: Pet Health and Farm Animal. The Pet Health segment offers products for companion animals like dogs and cats, including parasiticides such as the Advantage family of products and Seresto flea and tick collars. The Farm Animal segment provides products for livestock and poultry, including vaccines, antibiotics, and feed additives like Rumensin for cattle. Elanco has a robust pipeline of new products in development, including potential blockbuster treatments for canine dermatology and parasites, as well as a feed additive to reduce methane emissions from cattle. In February 2024, the company announced plans to divest its aqua business to Merck for USD 1.3 billion to focus on its core pet and livestock segments. </div>

Elanco buys key U.K. manufacturing site for $25M (NYSE:ELAN)

Promoting the health, well-being, and ethical treatment of animals

Animal Therapeutics

Companies that offer specialized therapeutics for the diagnosis, treatment, and management of cancer in animals. This includes areas such as cancer diagnosis, surgery, chemotherapy, and immunotherapy.

Companies that develop vaccines and drugs for pets and livestock based on advanced research and biotechnologies such as DNA technology, with a specific focus on the treatment and prevention of diseases and medical conditions in animals.

Companies that use regenerative techniques and technologies to promote tissue repair, regeneration, and healing in animals. This involves stem cell therapy, platelet-rich plasma (PRP) therapy, tissue engineering, gene therapy, and wound healing treatments.

Companies that provide veterinary diagnostic services, which include a wide range of tests, procedures, and laboratory services to diagnose, monitor, and manage the health and well-being of animals. This includes laboratory testing, diagnostic imaging, endoscopy, and genetic testing.

Companies that provide specialized treatments aimed at extending the lifespan and improving the overall health and quality of life of animals, including companion animals and livestock. These approaches are designed to address the challenges of aging, prevent age-related diseases, and enhance the well-being of aging animals.

Driving livestock productivity using next-generation biotechnology

Livestock Biotech

Companies that offer solutions that edit (gene editing) or modify (gene modification) an animal's genome in a precise and targeted manner using methods such as TALEN's, CRISPR/Cas9, recombinant retroviruses, and sperm-mediated DNA transfer. The techniques change the existing genome to improve/express desired traits in livestock. The segment also covers companies that use an AI-based platform or otherwise to offer diagnostic testing services of the animal's genome that help livestock farmers identify genetic changes or diseases present in herds.

Companies that offer next-generation vaccines based on developments in DNA technology (e.g., mRNA vaccines) and biotechnology. The segment also includes medicines developed for the prevention and treatment of livestock diseases.

Companies that use a range of genetic techniques that can alter the DNA of animals more precisely than traditional breeding techniques. Techniques such as gender selection via sexed semen, genomic selection, or even gene editing methods like CRISPR are used to breed animals precisely with superior genetic traits.

Companies that produce natural ingredients or biological additives that can be added to animal feed for purposes such as improving nutrient uptake and the gut microbiome.

ANALYST_QUICK_TAKE

INCUMBENTS_PRESENT

<div>
 Global animal health and nutrition firm, Elanco, announced that their methane-reducing feed additive "Boaver" has met the FDA's safety and efficacy standards for usage in cattle after an extensive review over several years. "Boaver" works by blocking the enzyme in the cow's digestive system responsible for methane production.
 As noted by Elanco, the use of "Boaver" can potentially lead to a 30% reduction in methane emissions from cattle and may also create an additional revenue stream for farmers through carbon credit schemes.
 Elanco creates "Boaver" through a licensing agreement with Royal DSM. After obtaining approval, both companies have agreed to enhance their collaboration, with the possibility of Royal DSM increasing the distribution of "Bovaer" throughout North America, which includes regions such as Canada and Mexico.
</div> Analyst QuickTake: 
 Enteric fermentation, the process in ruminants' digestive system that releases methane emissions into the environment, is one of the leading causes of methane emissions in agriculture. Notable startups developing methane-reducing feed additives include <a href="https: 
//sp-edge.com/companies/1317279"> Blue Ocean Barns </a> , <a href="https: 
//sp-edge.com/companies/1167526"> Locus Animal Nutrition </a> , <a href="https: 
//sp-edge.com/companies/2355459"> Rumin8 </a> , and <a href="https: 
//sp-edge.com/companies/782959"> Volta Greentech </a> .

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