Poietis

Poietis is a French biotechnology company specializing in laser-assisted bioprinting technology for creating three-dimensional (3D) biological tissues. The company's patented Next Generation Bioprinting (NGB) platform combines laser-assisted bioprinting (LAB) and bio-extrusion techniques to produce highly complex 3D tissue models with superior cellular resolution, viability, and functionality.

Poietis' laser bioprinting process involves using a pulsed laser to deposit microscopic droplets of cell-laden bioinks onto a substrate layer by layer, enabling precise positioning of cells in 3D with micrometric resolution. This cytocentric approach allows cells to grow and develop in a more natural environment, facilitating morphogenesis and biological processes like cell differentiation, migration, multiplication, and metabolic activities. The NGB platform incorporates automation, robotics, and various sensors, including a time-lapse imaging module for real-time monitoring of cell development at a cellular level.

The NGB platform is available in two versions: NGB-R for research applications and NGB-C for clinical use. The NGB-C is a GMP-compliant system designed for manufacturing human living tissues in an aseptic, closed environment within an isolator, ensuring repeatability and traceability of operations. It integrates a Stäubli TX2-40 Stericlean robot, chosen for its cleanability, sterilizability, and precision.

With its cutting-edge bioprinting capabilities, Poietis aims to accelerate the translation of 3D bioprinting research into clinical and commercial applications. The company has established partnerships with industry giants like BASF for developing cosmetic skin models and Servier Laboratories for creating liver toxicity detection models.