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Regenerative Medicine

Novel therapies to reboot cells and organs

Overview

The regenerative medicine (RM) industry deals with regrowing, repairing, or replacing cells, tissues, or organs. RM treatments are mostly applied in oncology, orthopedics, and dermatology to treat bone injuries, bone decay, burns, and skin damage. However, usage in cardiovascular and neuro-related diseases is also increasing, as more treatments receive regulatory approval. RM targets the root cause of a disease, providing potential cures rather than just addressing symptoms like most other common treatments (e.g., drugs and surgeries). 

There are three main types of RM: cell therapy, gene therapy, and tissue engineering. Cell therapy, the most common type, introduces a cell into a patient's body to repair or replace damaged cells. Meanwhile, gene therapy modifies or introduces new genes into the body to treat the disease, while tissue engineering replaces or builds new tissues around damaged organs; these are, however, yet to gain prominence in the RM market.

Note: Currently, we do not actively cover this industry, but we have identified it as a potential industry to cover.

More details

Market Mapping


Incumbents
Growth
Early
Seed
Pre-Seed
R&D Cell Therapy
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R&D Gene Therapy
?
Tissue Engineering Therapies
?
Cell culture and biomaterial manufacturing
?
Treatment Centers/Clinics
?
International
International
International
International
International
Bayer
GSK
Astellas Pharma
Johnson & Johnson
Novartis
Roche
Pfizer
Sana Biotechnology
Catalent Pharma Solutions
Rubius Therapeutics
Mesoblast
Codiak Biosciences
Athersys Inc
Avita Medical
Caladrius Biosciences
Pluristem Therapeutics
Bone Therapeutics
BioCardia
Regeneus
Celularity
ArsenalBio
Tenaya Therapeutics
Senti Biosciences
Cellular Biomedicine Group
Cellectis
Neurona Therapeutics
Jasper Therapeutics
Celyad
Vericel Corporation
Cellino Biotech
Histogen
DiscGenics
Capricor Therapeutics
Novadip Biosciences
InGeneron
TC Biopharm
Gameto
ArunA Biomedical
Celltex Therapeutics
Orgenesis
Kadimastem
Aegle Therapeutics
Hemostemix
Vascugen
Longeveron
RepliCel Life Sciences
Organicell Regenerative Medicine
Cytori Therapeutics
Orthocell
CellProthera
Targazyme
Eli Lilly
Sanofi
Novartis
Sarepta Therapeutics
Catalent Pharma Solutions
Generate Biomedicines
Ocugen
MeiraGTx
Tenaya Therapeutics
Applied Genetic Technologies Corporation
Affinia Therapeutics
SparingVision
Vivet Therapeutics
Coave Therapeutics
Avrobio
Orig3n
Juventus Therapeutics
Orgenesis
Abbvie
Integra LifeSciences
Johnson & Johnson
DSM Biomedical
Stryker
Organogenesis
Embody
Cook Biotech
Integra LifeSciences
MiMedx Group
ViaCyte
Avita Medical
Nanofiber Solutions
HCS Pharma
Curasan
Bico
Fractyl Health
AgomAb Therapeutics
Histogen
Miromatrix Medical
AxoGen
Prellis Biologics
Aziyo Biologics
Locate Bio
Healionics
Pandorum Technologies (India)
BioAesthetics
Tensive
Videregen
SweetBio
Atreon Orthopedics
Orthocell
Acuitive Technologies
Enzyvant
Cytonics
Invibio
Sana Biotechnology
Bico
Celularity
Cellectis
Organovo Holdings
StemBioSys
4D Biomaterials
Exopharm
Oxford Biomaterials
The Regenerative Clinic
Regenexx
Wellbeing International Foundation
Nordquist Regenerative Medicine

The Disruptors


R&D Cell Therapy

?

Disruptors

?
Funding in USD Millions
Catalent Pharma Solutions
Public - Market cap USD 13.0 bn
Sana Biotechnology
Public - Market cap USD 1.1 bn
Vericel Corporation
Public - Market cap USD 1.1 bn
Athersys Inc
Public - Market cap USD 564.5 mn
Mesoblast
Public - Market cap USD 373.6 mn
Celularity
Public - Market cap USD 329.0 mn
Capricor Therapeutics
Public - Market cap USD 146.1 mn
Tenaya Therapeutics
Public - Market cap USD 120.0 mn
Cellectis
Public - Market cap USD 108.6 mn
Longeveron
Public - Market cap USD 77.7 mn
Orthocell
Public - Market cap USD 56.4 mn
Rubius Therapeutics
Public - Market cap USD 39.2 mn
Celyad
Public - Market cap USD 38.1 mn
Caladrius Biosciences
Public - Market cap USD 36.2 mn
BioCardia
Public - Market cap USD 34.5 mn
Codiak Biosciences
Public - Market cap USD 28.1 mn
Pluristem Therapeutics
Public - Market cap USD 25.4 mn
Hemostemix
Public - Market cap USD 10.7 mn
TC Biopharm
Public - Market cap USD 7.9 mn
Histogen
Public - Market cap USD 3.4 mn
RepliCel Life Sciences
Public - Market cap USD 3.2 mn
ArsenalBio
306
Senti Biosciences
216
Cellular Biomedicine Group
204
Avita Medical
179
Neurona Therapeutics
157
Jasper Therapeutics
149
Cellino Biotech
98
Bone Therapeutics
82
DiscGenics
68
Novadip Biosciences
54
InGeneron
51
Gameto
40
ArunA Biomedical
35
Celltex Therapeutics
34
Orgenesis
29
Kadimastem
22
Aegle Therapeutics
14
Vascugen
11
CellProthera
9
Organicell Regenerative Medicine
5
Targazyme
3
Cytori Therapeutics
Unknown
Regeneus
Unknown

R&D Gene Therapy

?

Disruptors

?
Funding in USD Millions
Catalent Pharma Solutions
Public - Market cap USD 13.0 bn
Sarepta Therapeutics
Public - Market cap USD 9.7 bn
Ocugen
Public - Market cap USD 385.5 mn
MeiraGTx
Public - Market cap USD 378.5 mn
Tenaya Therapeutics
Public - Market cap USD 120.0 mn
Avrobio
Public - Market cap USD 28.1 mn
Applied Genetic Technologies Corporation
Public - Market cap USD 18.4 mn
Generate Biomedicines
420
Affinia Therapeutics
170
SparingVision
128
Vivet Therapeutics
93
Coave Therapeutics
92
Orig3n
76
Juventus Therapeutics
49
Orgenesis
29

Tissue Engineering Therapies

?

Disruptors

?
Funding in USD Millions
Integra LifeSciences
Public - Market cap USD 3.5 bn
AxoGen
Public - Market cap USD 504.0 mn
Organogenesis
Public - Market cap USD 424.1 mn
MiMedx Group
Public - Market cap USD 326.1 mn
Bico
Public - Market cap USD 214.8 mn
Aziyo Biologics
Public - Market cap USD 98.1 mn
Miromatrix Medical
Public - Market cap USD 91.5 mn
Orthocell
Public - Market cap USD 56.4 mn
Histogen
Public - Market cap USD 3.4 mn
Fractyl Health
255
ViaCyte
236
Avita Medical
179
AgomAb Therapeutics
136
Prellis Biologics
65
Embody
48
Locate Bio
22
Healionics
17
Pandorum Technologies (India)
14
BioAesthetics
7
Tensive
5
Videregen
5
Nanofiber Solutions
5
Cytonics
3
HCS Pharma
2
Atreon Orthopedics
Unknown
Curasan
Unknown
Acuitive Technologies
Unknown
Enzyvant
Unknown
Cook Biotech
Unknown
Watchlist
?
SweetBio

Cell culture and biomaterial manufacturing

?

Disruptors

?
Funding in USD Millions
Sana Biotechnology
Public - Market cap USD 1.1 bn
Celularity
Public - Market cap USD 329.0 mn
Bico
Public - Market cap USD 214.8 mn
Cellectis
Public - Market cap USD 108.6 mn
Organovo Holdings
Public - Market cap USD 17.9 mn
StemBioSys
14
4D Biomaterials
3
Exopharm
Unknown
Invibio
Unknown
Oxford Biomaterials
Unknown

Treatment Centers/Clinics

?

Disruptors

?
Funding in USD Millions
Regenexx
Unknown
Wellbeing International Foundation
Unknown
The Regenerative Clinic
Unknown
Nordquist Regenerative Medicine
Unknown

Catalent Pharma Solutions

Catalent is a listed company that collaborates with pharmaceutical companies, biotech companies and other stakeholders in the pharmaceutical industry in order to enable drug delivery, development and supply management. The company specializes in the manufacturing of softgel products, which is a method of oral drug delivery for patients, and inhalation products. Catalent also provides customized clinical supply management services for smaller pharmaceutical companies. The company has a global presence with service centers, research and production facilities in Europe and Asia in addition to the Americas.

Segment:
R&D Cell Therapy
Total funding:
USD 550.0 million
Disruptor Funding History

R&D Cell Therapy:

Catalent Pharma Solutions
Sana Biotechnology
Vericel Corporation
Athersys Inc
Mesoblast
Celularity
Capricor Therapeutics
Tenaya Therapeutics
Cellectis
Longeveron
Rubius Therapeutics
Celyad
Caladrius Biosciences
BioCardia
Codiak Biosciences
Pluristem Therapeutics
Hemostemix
TC Biopharm
Histogen
RepliCel Life Sciences
ArsenalBio
Senti Biosciences
Cellular Biomedicine Group
Avita Medical
Neurona Therapeutics
Jasper Therapeutics
Cellino Biotech
Bone Therapeutics
DiscGenics
Novadip Biosciences
InGeneron
Gameto
ArunA Biomedical
Celltex Therapeutics
Orgenesis
Kadimastem
Aegle Therapeutics
Vascugen
CellProthera
Organicell Regenerative Medicine
Targazyme

R&D Gene Therapy:

Catalent Pharma Solutions
Sarepta Therapeutics
Ocugen
MeiraGTx
Tenaya Therapeutics
Avrobio
Applied Genetic Technologies Corporation
Generate Biomedicines
Affinia Therapeutics
SparingVision
Vivet Therapeutics
Coave Therapeutics
Orig3n
Juventus Therapeutics
Orgenesis

Tissue Engineering Therapies:

Integra LifeSciences
AxoGen
Organogenesis
MiMedx Group
Aziyo Biologics
Miromatrix Medical
Histogen
Fractyl Health
ViaCyte
Avita Medical
AgomAb Therapeutics
Prellis Biologics
Embody
Locate Bio
Healionics
Pandorum Technologies (India)
BioAesthetics
Tensive
Videregen
Nanofiber Solutions
Cytonics
HCS Pharma
SweetBio

Notable Investors


No investor data is available

Funding data are powered by Crunchbase
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