National Science Foundation (NSF) is an independent federal agency that supports research and education in science and engineering. It provides up to $1.5 million in non-dilutive funding to startups working in various areas of science and technology to support research and development (R&D) and mitigate technology risks for commercial success. This funding is part of America's Seed Fund, which is mandated by Congress through the Small Business Innovation Research (SBIR) program. The NSF operates with a budget of approximately $7.8 billion and funds fundamental research and education across all fields of science and engineering.

National Science Foundation

CULT Food Science is an investment company focused on supporting and advancing the technology behind the future of food. It identifies and makes equity investments in global cultivated meat and dairy companies that are developing and commercializing innovative food technologies that enable a kinder, more secure, and more sustainable food supply chain.

Cult Food Science

Social Starts is a venture capital firm with a data-driven approach to investing in moment-of-inception and Series A financing rounds. The firm prefers to invest in early-stage companies operating in the technology, health tech, internet, and mobile tech sectors.

Social Starts

Big Idea Ventures is the world’s most active investor in FoodTech investing in the best food technology and agritech companies globally. The company is focused on alternative protein with its New Protein Fund and commercialization of university intellectual property with its Generation Food Rural Partners fund. BIV is backed by a strong network of strategic partners including AAK, Avril, Bühler, Givaudan, Temasek Holdings, and Tyson Ventures, and is partnering with governments around the world working on food security and new food ecosystems. The firm has offices in New York, Paris and Singapore and has invested in more than 100 companies across 22 countries. For more information, visit bigideaventures.com

Big Idea Ventures

SFV backs globally early-stage founders building leading Future of Food companies that are: #Cell-based #Plant-based #Recombinant

Sustainable Food Ventures

Good Startup is a venture firm focused on the alternative protein sector.

Good Startup

Novel Farms

Novel Farms uses microbial fermentation to develop cruelty-free, inexpensive and tunable bioscaffolds for the production of cell-based meat products. Novel Farms mission is to craft the taste and texture of the gourmet meats and transform cell-based meat consumption into a sought-after culinary experience for the next generation of conscious eaters.

Novel Farms is a startup that uses synthetic biology to develop 3D bio scaffolding to produce its whole-cut gourmet cell-cultured meat.

Making meat sustainable over the long term

Cell-cultured Meat

Novel Farms Co-founders Named as Breakthrough Energy Fellows

Novel Farms is a startup that uses synthetic biology to develop 3D bio scaffolding to produce its whole-cut gourmet cell-cultured meat.Novel Farms claims that its cultured steak has improved structure and taste similar to slaughtered steak by using technology that enhances the culturing of fat and muscle cells to achieve marbling. In <a href="https://sp-edge.com/updates">August 2022 </a>, the company developed what it claims to be the world’s first lab-grown pork loin using a proprietary microbial fermentation process that reduced production costs by 99.27%.Funding and financialsIn <a href="https://sp-edge.com/updates/12292">August 2022 </a>, the company raised USD 1.4 million in a pre-seed funding round backed by Big Idea Ventures Joyance, Sustainable Food Ventures, and CULT Food Science Corp, among others. The funds were planned to help with additional hires and scaling up of production.Further, in <a href="https://sp-edge.com/updates/22248">September 2023 </a>, Novel Farms received a USD 999,967 Small Business Innovation Research (SBIR) Phase II grant from the National Science Foundation (NSF). The funding was earmarked for team expansions and scaling its proprietary scaffolding platform.

Mosa Meat is a Dutch cell-cultured meat startup founded by Dr. Mark Post of Maastricht University, and was the first-ever company to produce a lab-grown meat burger. The startup produces meat by growing myosatellite cells (muscle stem cells) extracted from an animal in a bioreactor fed with a nutrient-dense medium.The company replaced the fetal bovine serum (FBS) from its growth medium in July 2020, which led to an 88x cost reduction in its medium. As of March 2024, Mosa Meat operated the Center for Advanced Meat Production, Upscaling, and Sustainability (CAMPUS), a facility spanning over 79,000 sq ft that was designed to be expandable as demand grows.In <a href="https://sp-edge.com/updates/21645">September 2023</a>, Mosa Meat became the first cultivated meat company to attain B Corp certification. The company also announced plans to apply for regulatory approval in countries worldwide. In <a href="https://sp-edge.com/updates/21645">September 2023</a>, Mosa Meat became the first cultivated meat company to attain B Corp certification. The company also announced plans to apply for regulatory approval in countries worldwide. In <a href="https://sp-edge.com/updates/31970">July 2024</a>, it conducted the first official tasting of its cultivated beef product, the Mosa Burger, in the Netherlands. This event gathered Dutch cattle farmers, food product developers, and industry representatives to collect expert feedback.Key customers and partnershipsIn <a href="https://sp-edge.com/updates/14175">November 2022</a>, Mosa Meat entered into an agreement with Singapore-based contract development and manufacturing organization (CDMO) Esco Aster to commercialize its cultivated beef in Singapore. Further, in <a href="https://sp-edge.com/updates/16845">March 2023</a>, the company partnered withNutreco to develop a cell feed supply chain that can expedite production and scalability while reducing cost.Funding and financialsIn its latest funding round in <a href="https://sp-edge.com/updates/28536">April 2024</a>, the company raised EUR 40 million (~USD 42.5 million) in an oversubscribed funding round co-led by Lowercarbon Capital and M Ventures, with participation from PHW Group, Invest-NL, LIOF, and LEF. The funds were earmarked for scaling production procedures, reducing production costs, and gearing up for commercialization.

Mosa Meat

SuperMeat is a cellular agriculture startup developing cultured chicken meat. The company uses chicken cells and claims to grow them in a culture medium free from antibiotics and contaminants to develop its products. SuperMeat also operates a test kitchen known as The Chicken. It is claimed to be the world’s first farm-to-fork facility where diners can observe the production of cultivated chicken.In <a href="https://sp-edge.com/updates/21733">September 2023</a>, The Orthodox Union (OU) certified SuperMeat’s cultivated chicken as “kosher.” Further, the OU and SuperMeat will collaborate on establishing guidelines for the industry.In&nbsp;<a href="https://sp-edge.com/updates/35765">November 2024</a>, the company announced it had achieved cost parity for its cultivated chicken and could produce it at at USD 11.79 per pound at scale, matching the price of premium US pasture-raised chicken.Key customers and partnershipsIn <a href="https://sp-edge.com/updates/9319">March 2022</a>, SuperMeat signed an MoU with PHW to supply cultivated meat products including chicken, turkey, and duck to the European market. The company also <a href="https://sp-edge.com/updates/8997">partnered</a> with Ajinomoto to set up a joint venture to accelerate the commercialization of cultivated meat while focusing on developing a cost-competitive cell growth media.In <a href="https://sp-edge.com/updates/11867">July 2022</a>, the company signed an MoU with Switzerland’s largest retail supermarket chain and leading meat manufacturer, Migros to expedite production and distribution of cultured meat at a commercial scale with a focus on European markets.&nbsp;

SuperMeat

Uncommon (formerly HigherSteaks) is a UK-based cell-cultured meat startup that uses cellular agriculture to grow pork from animal cells. The company leverages cellular agriculture and in-house developed RNA technologies to cultivate meat and claims its technology eliminates the need for genetic engineering and growth media.In July 2020, the company unveiled the world's first lab-grown pork belly prototype and the second cell-based bacon (behind Mission Barns cell-based bacon unveiled in early 2020). The pork belly and the bacon were produced from a combination of cell-cultured muscle and plant-based proteins and fat. Uncommon plans to commercialize its cell-cultured meat by 2022-2025, pending regulatory approval.Funding and financialsIn <a href="https://sp-edge.com/updates/19267">June 2023</a>, the company raised USD 30 million in Series A funding co-led by Balderton Capital and Lower Carbon Capital, with participation from Redalpine, East Alpha, and others. The funds were earmarked for the development of its innovative approach, expanding production, increasing the team, and initiating regulatory approvals.

Uncommon

Multus, a spin-off of SOSV’s IndieBio program, is a biotechnology company that specializes in the development of growth media solutions for cellular agriculture applications. Its portfolio includes serum-free FBS alternatives (Proliferum M and Proliferum LSR) and solutions that support cell adhesion (rh-Vitronectin) during the cultivation process.Multus leverages MediOp, a growth media formulation design platform, to develop its solutions. According to the company, this technology allows optimizing solutions using automated data analysis and insights. Multus also uses this platform to provide contract manufacturing services for custom formulation design and food-safe manufacturing compliant with ISO22000 to customers in North America, Europe, and Asia-Pacific.In <a href="https://sp-edge.com/updates/25572">January 2024</a>, the company unveiled what it claims to be the first large-scale production plant making serum-free growth media in the cultivated meat industry.Key customers and partnershipsIn <a href="https://sp-edge.com/updates/24911">December 2023</a>, the company partnered with New Wave Biotech, a bioprocess optimization software company, under a project funded through an Innovate UK Engineering Biology grant. Through this partnership, Multus planned to use New Wave Biotech’s AI software to optimize its process of developing precision-fermented ingredients for cell cultivation.Funding and financialsIn <a href="https://sp-edge.com/updates/15702">January 2023</a>, the company raised GBP 7.9 million (~USD 9.6 million) in a funding round led by Mandi Ventures with participation from SOSV, Big Idea Ventures, and others. The funding from this round was earmarked for the development of its animal-free growth media production facility in London.

Multus

Based in Israel, Believer Meats (Future Meat Technologies prior to November 2022) develops hardware and cell lines for the manufacturing of cell-cultured meat, to commercialize its manufacturing hardware and techniques.Believer Meats uses fibroblast cells that can be triggered with small molecules to develop either fat or muscle cells. Fat and muscle cells are cultured in a unique bioreactor that removes the waste material from the media, allowing the company to recycle parts of the media to reduce feed media input by as much as 50%. The startup replaced FBS with molecules derived from Chinese hamster ovaries (CHO) to reduce production costs and plans to achieve price parity with animal counterparts.In <a href="https://sp-edge.com/updates/12623">August 2022</a>, the company announced it has developed what it claims to be the world’s first cultivated lamb, using cell lines isolated from Awassi sheep.In <a href="https://sp-edge.com/updates/15195">December 2022</a>, the company announced it has begun development of a 200,000 sq foot production facility in Wilson, North Carolina with an annual capacity of ~22 million lbs, which is claimed to be the largest cultivation facility in the world. Believer Meats plans to produce cultured chicken, pork, beef, and lamb for US, European, and Asian markets.Key customers and partnershipsIn March 2022, the company <a href="https://sp-edge.com/updates/9320">partnered</a> with Charoen Pokphand Foods to develop cultivated meat products for Asia.In <a href="https://sp-edge.com/updates/17710">April 2023</a>, Believer Meats signed an MoU with Archer Daniels Midland (ADM) to collaborate on the development and commercialization of cultivated meat products. Further, ADM will offer its ingredient pantry and nutrition knowledge to enhance Believer's cell-cultivated meat process.In <a href="https://sp-edge.com/updates/30520">June 2024,</a> Believer Meats partnered with Abu Dhabi’s AgriFood Growth &amp; Water Abundance (AGWA), to advance cultivated meat production in the MENA region.Funding and financialsIn its <a href="https://sp-edge.com/updates/9252">latest funding round</a> in December 2021, the company raised USD 347 million in Series B funding, recording the largest investment in cell-cultured meat at the time. The round was co-led by ADM Ventures, while funds were to be used to accelerate its production plans in the US.

Believer Meats

Producers of cell-cultured seafood using cells extracted from fish. Startups have succeeded in developing prototypes of yellowtail and salmon

Producers of cell-cultured pork using cells extracted from animals. Startups have succeeded in developing prototypes of bacon and pork belly using cultured muscle and plant-based proteins and fat

Producers of cell-cultured beef using cells extracted from animals. Some producers in the industry are developing premium beef ranges such as Wagyu. Startups have only succeeded in developing prototypes in the minced form, with a few creating prototypes of (pieces of) steak using 3D bioprinters

Producers of cell-cultured chicken and duck using cells extracted from animals. Some producers in the industry are developing rare delicacies such as foie gras. Startups have only succeeded in developing products in the nugget form

Producers of growth media for cell-cultured meat production and ingredients for meat and meat analog (cell-cultured, plant-based) producers, which can include cell culture meat paste, culture fat, etc. Producers of growth media mainly focus on developing alternative growth media to FBS using plant-based or other sources

Developers of bioreactors and other technologies used in cell-cultured meat production. Industrial scaling and efficiency gains are key areas of interest for startups in the industry

Provide sustainable solutions for animal slaughter through the use of biotechnology

California-based FoodTech startup, Novel Farms, has secured a USD 999,967 Small Business Innovation Research (SBIR) Phase II grant from the National Science Foundation (NSF). The grant will be used to support the company's efforts in reducing media costs by developing its proprietary scaffolding technology. Novel Farms plans to use the funding to expand its team and scale its process from the bench to bioreactor level. This milestone highlights the company's commitment to innovation and sustainable food production.

Novel Farms

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