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Histogenics is a regenerative medicine company focused on developing and commercializing products in the musculoskeletal segment of the marketplace. Our regenerative medicine platform combines expertise in cell processing, scaffolding, tissue engineering, bioadhesives and growth factors to provide solutions that can be utilized individually or in concert to treat musculoskeletal-related conditions. Our first investigational product candidate, NeoCart®, leverages our platform to provide an innovative treatment in the orthopedic space, specifically cartilage damage in the knee.

Stryker is a medical technology company that offers products and services in orthopaedics, medical, surgical, and spine by focusing on their key values that help improve patient and hospital outcomes. They are driven to make healthcare better that meet regulatory requirements through their effective quality system.

<div> Stryker Corporation (NYSE: SYK) is a multinational MedTech company based in Michigan. The company develops and produces medical implants, surgical and imaging technologies, and patient handling and emergency medical equipment. Stryker has been listed on the NYSE since 1979 and generated revenue of USD 18.4 billion in 2022. Stryker segregates its operations into two reportable segments: MedSurg and Neurotechnology as well as Orthopaedics and Spine. MedSurg includes surgical equipment, endoscopic devices, along with patient handling and emergency medical equipment, among others. Neurotechnology includes neurosurgical, neurovascular, and craniomaxillofacial implant products. Orthopedics products consist primarily of implants used in total joint replacements, such as hip, knee, and shoulder, along with trauma and extremities surgeries. The Spinal segment includes cervical and thoracolumbar systems and a spine enabling technologies portfolio.&nbsp; Stryker products are sold in more than 75 countries. The US is the company&rsquo;s largest market (~74% of total revenue in 2022), followed by the Europe, Middle East, and Africa (EMEA) and Asia-Pacific regions. Stryker expects its organic net sales growth to be between 7%&ndash;8.5% in 2023 and has been working toward carbon-neutralizing all its facilities by 2030. </div>

Stryker declares an $0.84 per share quarterly dividend

Technologies bringing about a new reality

Extended Reality

Companies developing XR headsets and relevant sub-components (displays, sensors, and processors). Also includes complementary XR hardware (tracking devices, haptic vests, and gloves)

Companies offering engines that enable the development of AR/VR content, also includes companies offering capabilities to capture and create 3D images for immersive environments

Companies offering AR/VR solutions or toolkits for specific industry applications, including VR game developers

Companies offering location-based AR/VR experiences

Pushing the envelope in MedTech with emerging technologies

Next-gen Medical Devices

Companies that develop diagnostic devices used in a hospital setting to identify a disease, condition, or injury, such as imaging systems and endoscopes

Companies that develop implantable medical devices designed to be surgically placed inside the human body, either temporarily or permanently, including devices such as pacemakers, artificial joints, stents, and cochlear implants

Companies that develop non-surgical devices that are used in a procedure or intervention to cure or relieve a patient from an illness or disease such as laser treatments, dental equipment, and wound care management

Companies that develop monitoring devices that are used in a hospital setting to measure patient vital signs and ensure patient well-being post-treatment, such as cardiac and respiratory monitoring systems

Providers of software that enhances the functionality of medical device hardware (diagnosis, treatment, and monitoring)

Companies that develop surgical devices involving invasive interventions (cutting into a patient's body tissues) to treat, cure, or relieve a patient of an illness or disease

Companies that develop devices to administer pharmaceutical substances into a patient's body, ensuring controlled release or targeted delivery, specifically for use in clinical settings to treat or manage medical conditions effectively

Providers of software that helps manage risks, ensure quality, and streamline audit processes during medical device development

ANALYST_QUICK_TAKE

INCUMBENTS_PRESENT

<div>
 Stryker, a leading medical technology company, has recently taken over Vertos Medical, a firm known for its speciality in interventional pain management solutions. This acquisition is particularly focused on dealing with chronic lower back pain resulting from lumbar spinal stenosis.
 The major aim of this strategic acquisition is to strengthen Stryker's non-surgical solutions aimed at addressing chronic lower back pain. Furthermore, it aims to expand Stryker's influence in ambulatory surgery centers. This move is expected to solidify Stryker's position in the healthcare industry.
 Vertos Medical has a unique portfolio, especially in the field of interventional pain management. Of notable mention is its minimally invasive mild procedure that has been helping patients suffering from chronic lower back pain regain their normal lifestyle. This specific procedure has contributed significantly to the standing of Vertos Medical and is a major factor in its acquisition by Stryker. 
</div> Analyst Quicktake: 
 Stryker continues to make M&amp;A moves across multiple applications. Other deals made during the recent months include the acquisitions of Molli Surgical ( <a href="https: 
//www.stryker.com/us/en/about/news/2024/stryker-completes-acquisition-of-molli-surgical.html"> July 2024 </a> ), Artelon ( <a href="https: 
//www.stryker.com/us/en/about/news/2024/stryker-completes-acquisition-of-artelon-inc.html"> July 2024 </a> ), and SERF SAS ( <a href="https: 
//www.stryker.com/us/en/about/news/2024/stryker-completes-acquisition-of-serf-sas.html"> March 2024 </a> ).

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