GlycanAge

GlycanAge provides a biological age test based on measuring chronic inflammation in one’s system, which is directly related to their lifestyle and provides professional advice based on these test results.

The company claims that the test is based on over 25 years of scientific research and has carried out more than 200,000 tests. The uniqueness of the test is that it integrates genetic, epigenetic, and environmental aspects of aging and responds to lifestyle interventions.

GlycanAge determines biological age by looking at the state of the immune system and inflammation by analyzing the glycans attached to the most common antibody in blood, called “Immunoglobulin G” or IgG. The type of glycans attached to IgG can change the function of IgG from pro-inflammatory to anti-inflammatory and vice versa. While both functions are needed for a strong immune system, the balance between them will affect the health status and consequently the biological age. GlycanAge does not measure glycation. Instead, it measures glycosylation. Glycation happens when glucose attaches to proteins as a random chemical process, while glycosylation is a highly regulated process that adds a specific type of sugar to a specific part of a protein during protein synthesis.