Sequoia is a venture capital focused on energy, financial, enterprise, healthcare, internet, and mobile startups. The firm helps a small number of daring founders build legendary companies. It spurs them to push the boundaries of what’s possible. The firm seeks to invest in all sectors with a focus on energy, financials and financial services, healthcare and healthcare services, Internet, mobile, outsourcing, and technology.

Sequoia Capital

Corner Ventures, re-branded from DAG Ventures (c. 2004) in 2018, with offices in Silicon Valley, New York, Tel Aviv and Tokyo, focuses on building category leading companies in a variety of industries including information technology, cyber-security, financial services, healthcare, software among others.

Corner Ventures

ICONIQ Growth partners with exceptional entrepreneurs and leaders who drive global impact and change. The firm is inspired by visionaries defining the future of their industries by building company cultures that endure. ICONIQ Growth has a unique investment platform harnesses the power of ICONIQ Capital’s vibrant ecosystem of founders, pioneers, and business leaders with the goal of delivering tangible value and amplifying our portfolio companies’ success from early growth stage to IPO and beyond. ICONIQ Growth’s portfolio of innovators includes Adyen, AirBnB, Alibaba, Alteryx, Automattic, BambooHR, Braze, Chime, Collibra, Coupa, Datadog, Docusign, Gitlab, Marqeta, Miro, Procore, Red Ventures, Relativity, ServiceTitan, Snowflake, Sprinklr, Truckstop, Uber, Wolt, and Zoom, among others.

ICONIQ Growth

Perceptive Advisors is a privately owned hedge fund sponsor. The firm invests in the public equity markets across the globe. It employs a long/short equity strategy as a hedging technique while investing. The firm typically invests in the biotechnology and life sciences sectors to make its investments. Perceptive Advisors is based in New York, New York.

Perceptive Advisors

Sofina is an investment company that provides minority investments, private funds, guidance, market knowledge, networking, and investment services. They invests both directly and through Private Equity funds. They provide patient capital and advice to growing companies led by entrepreneurs and families and to support them as a long-term partner with other investors.

Sofina

Helena is an organization of thirty global influencers who work together to achieve positive world impact.  The group collaborates to create breakthrough ideas, then leverages its collective reach, strategic partnerships, and network to make them happen.  Half of Helena's members are under the age of twenty-five, and half are older than twenty-five. Every Helena member represents the pinnacle of accomplishment in their field.  They have fought diseases, created currencies, and commanded armies. They have disrupted industries, overcome oppression, and discovered technologies. They are actors, linguists, economists, biochemists, activists, technologists, explorers, financers, filmmakers, and much more.  The result is a broad and powerful platform that spans talents, skills, and generations. When Helena's members collaborate, their diverse abilities, generational experiences and influence come together to address issues, advance technologies, and guide movements in previously unexplored ways.

Helena

Peak XV Partners (Formerly Sequoia Capital India & SEA) is a venture capital and growth investment firm investing across India, South East Asia, and beyond. Peak XV has grown to manage over $9bn in capital across 13 funds and invested in over 400 companies, of which ~40 companies have achieved revenues of over $100MM.

Peak XV Partners

LTS represents the holding company and investment office of the Lemann, Telles and Sicupira families, as well as some of their longtime partners. The partners have been responsible for developing several businesses over the last 40 years. We are responsible for providing support to our partners' existing investments and for sourcing new investment opportunities. We have a flexible mandate in terms of region, sector and stage. Our purpose is to support outstanding leaders and entrepreneurs in achieving their big dreams.

LTS Investments

Temasek Holdings is a lender provider. The company offers debt financing and focuses on transforming economies, increasing middle-income populations, developing comparative advantages, and emerging champions. Financial services, transportation, industrial, consumer, real estate, telecommunications, media, technology, and life sciences are among the industries served by the firm.

Temasek Holdings

Twin Health

Twin Health is a Precision Health platform combining Sensors, Machine Learning, and Medical Science to reverse chronic diseases and improve human metabolic health. They are backed by leading VC firms Iconiq Capital, Temasek, Sequoia Capital, Perceptive Advisors, Corner Ventures, LTS Investments, Helena, and Sofina with $249M in funding through Series D. Twin has developed unique patent-pending technology (3 patents granted, 7 patents pending) to analyze complex biosignals from wearable sensors, predict metabolic outcomes using ML, and recommend highly-personalized treatments based on the metabolic profile of each patient.

Twin Health is a healthcare technology company that has developed the Whole Body Digital Twin, an AI-powered platform that helps individuals reverse and prevent chronic metabolic diseases such as type 2 diabetes, obesity, fatty liver, and dyslipidemia. The technology provides a digital representation of an individual's metabolism, built from thousands of data points collected daily via wearable sensors, clinical lab parameters, and self-reported preferences.

Membership-based, non-insurance healthcare companies helping maintain a steady state of well being.

Preventive Healthcare

Twin Health is a healthcare technology company that has developed a patented "Whole Body Digital Twin" service to reverse, improve, and prevent chronic metabolic diseases such as type two diabetes, obesity, fatty liver, and dyslipidemia. Their solution is available through employer and health plan partners. The Whole Body Digital Twin is a dynamic model of an individual's unique metabolism, built using artificial intelligence and data from wearable sensors, clinical lab parameters, and self-reported preferences. It provides personalized, precise, and timely guidance across nutrition, sleep, activity, and stress through an easy-to-use app.

Twin Health conducts study on its AI-enabled medical therapy for Type 2 diabetes remission

IIT Madras Research Park Validates Twin Health’s Digital Twin & AI for Diabetes Reversal

TWIN HEALTH SECURES $50M TO EXPAND ITS GROUNDBREAKING WHOLE BODY DIGITAL TWIN™ TECHNOLOGY AND SERVICE TO REVERSE CHRONIC METABOLIC DISEASE

Real results for real people

From counting steps to saving lives and beyond

Wearable Tech

Twin Health Announces Digital Twin AI for Sustainable Weight Loss with GLP-1 Elimination

Twin Health is a digital chronic metabolic disease prevention startup. Its AI-powered platform provides a digital representation of an individual's metabolism, enabling users to reverse or prevent chronic metabolic diseases such as type 2 diabetes. Healthcare providers and Twin coaches are able to consult patients, continuously monitor vitals using connected devices, and offer quick interventions via the platform. Additionally, Twin’s mobile app provides personalized guidance on nutrition, sleep, activity, and breathing to users.Funding and financialsIn <a href="https://sp-edge.com/updates/24899">December 2023</a>, the company secured USD 50 million in an investment round led by Temasek. The new funds were used to enhance its technology and clinical service solutions, aiming to extend its footprint across the US.

Twin Health is a healthcare technology company that has developed the Whole Body Digital Twin, an AI-powered platform that helps individuals reverse and prevent chronic metabolic diseases such as type 2 diabetes, obesity, fatty liver, and dyslipidemia. The technology provides a digital representation of an individual's metabolism, built from thousands of data points collected daily via wearable sensors, clinical lab parameters, and self-reported preferences.Healthcare providers and Twin coaches are able to consult patients, continuously monitor vitals using connected devices, and offer quick interventions via the platform. Additionally, Twin’s mobile app provides personalized guidance on nutrition, sleep, activity, and breathing to users. In May 2024, the company launched the Healthy Weight solution, which focuses on sustainable weight loss and medication elimination.Key customers and partnershipsIn May 2024, the company partnered with employers such as Applegreen, Bayview, and Dayforce to deploy its Healthy Weight solution.Funding and financialsIn <a href="https://sp-edge.com/updates/24899">December 2023</a>, the company secured USD 50 million in an investment round led by Temasek. The new funds were used to enhance its technology and clinical service solutions, aiming to extend its footprint across the US.

Cardiomo Care is developing noninvasive wearable devices to alert users and caretakers when there are abnormalities in the heartbeat. The company’s AI engine, trained on existing and growing data sets, can predict potential heart issues up to two hours before they occur, enabling early detection and intervention for arrhythmias and other cardiovascular diseases (CVDs).The company's product, CardiomoPatch, is a waterproof, wearable patch capable of long-term wear with a 10-day battery life. The patch monitors a patient's cardiac data, including ECG outputs, breathing, and skin temperature, and transmits the data via a mobile app for analysis by Cardiomo's AI engine.&nbsp;As of May 2024, the company is yet to commercialize its product and has over 1,600 pre-orders.

Cardiomo Care

Omada is a prevention-focused digital therapeutics startup that helps members achieve health goals through lifestyle changes. It offers four evidence-based, virtual prevention programs for managing hypertension, musculoskeletal (MSK) issues, prediabetes, and diabetes.Omada offers real-time data tracking through connected devices (such as wireless scales, blood pressure, and glucose monitors) and access to personalized coaching sessions via a mobile app as part of its prevention program. It also provides an online community of peers with similar health conditions to discuss challenges and provide support. In May 2021, Omada became the first fully-virtual healthcare provider to earn the National Committee for Quality Assurance’s Population Health Program Accreditation for its type 2 diabetes and type 2 diabetes + hypertension programs.Unlike its peers, Omada operates a performance-based business model where it charges clients an enrollment fee based on the number of users and a performance fee based on how much weight their employees lose. In May 2020, the company acquired virtual physical therapy startup Physera.Key customers and partnershipsAs of May 2024, Omada had more than 1 million members from more than 1,900 enterprise clients across all 50 US states. Its B2B employer and health plan client base include key clients such as American Eagle, Kaiser Permanente, Costco Wholesale, 3M, and Marvin. Additionally, the company has partnered with health systems and hospitals such as Intermountain Healthcare to provide its preventive programs as a covered benefit.In <a href="https://sp-edge.com/updates/15587">January 2023</a>, the company partnered with health service company Castell (a subsidiary of Intermountain Healthcare) to provide its diabetes programs to members from Intermountain Healthcare’s primary care providers in its Utah Medical Group. Further in <a href="https://sp-edge.com/updates/25245">January 2024</a>, the company partnered with Amazon to expand access to its cardiometabolic program.

Omada Health

VillageMD provides primary care services for patients. It also provides tools, technology, and staffing support needed for physicians to deliver high-quality services. VillageMD’s service delivery methods include traditional freestanding clinics, Village Medical at Walgreens co-located clinics, as well as at-home and around-the-clock virtual visits. It also leverages a team-based approach to care where physicians lead nurse practitioners, pharmacists, mental health specialists, and dietitians to offer a holistic care program. The technology of VillageMD includes docOS, an operating system that enables better patient care by connecting various clinical source systems with ongoing patient-generated data coupled with an AI engine to continuously analyze messages to enable patient self-care.The company made several acquisitions to expand its footprint: 1) <a href="https://sp-edge.com/updates/14347">Summit Health</a> for USD 8.9 billion in November 2022, 2) Healthy Interactions, an interactive patient education platform, in February 2022, and 3) <a href="https://sp-edge.com/updates/16968">Starling Physicians</a>, a primary care and specialty care provider, in March 2023.Key customers and partnershipsIn June 2020, VillageMD and Walgreens Boots Alliance announced a collaborative effort to open at least 600 Village Medical centers at Walgreens across more than 30 US markets by 2025. Walgreens invested USD 5.2 billion in VillageMD (from the previously announced USD 1.0 billion), raising its ownership stake to 63% (from 30%).However, as of May 2024, Walgreens had plans to close 160 VillageMD clinics as part of a cost-cutting plan.

VillageMD

Cityblock Health is a value-based healthcare provider focused on delivering comprehensive care to underserved communities, primarily Medicaid and lower-income Medicare beneficiaries. The company combines primary care, behavioral health, and social services to address the complex physical, mental, and social needs of its members.Cityblock's model involves partnering with local community-based organizations and deploying multidisciplinary care teams that include doctors, nurses, behavioral health specialists, and community health workers. These teams provide personalized care through 24/7 access to multi-modal care delivery, including in-home visits, telehealth, and community health hubs.The services of Cityblock are available to members at no additional cost if they are covered by an eligible health plan.Key Customers and PartnershipsAs of May 2024, the company’s services were available in seven states across the US and served over 100,000 members.In May 2024, it partnered with <a href="https://sp-edge.com/updates/29647">Sunshine Health</a> to expand to Florida, and, in <a href="https://sp-edge.com/updates/13270">September 2022</a>, it partnered with MDwise to expand into Indiana. Prior to that, the company had partnered with insurance providers such as ConnectiCare (Connecticut), Tufts Health Plan (Massachusetts), Emblem Health (New York), Healthy Blue (North Carolina), Molina Healthcare (Ohio) and CareFirst (Washington DC).Funding and FinancialsCityblock is a spin-off of Sidewalk Labs, an Alphabet company that incubates and invests in tech companies and products to improve urban infrastructure. It completed a USD 400 million Series D funding round led by Softbank in <a href="https://sp-edge.com/updates/5326">September 2021</a>, valuing the company at USD 5.7 billion. The funds were used to expand its services.

Cityblock Health

Everside Health (formerly Paladina Health) offers preventative care for chronic conditions and primary, mental and occupational healthcare treatments for acute conditions. Patients benefit from around-the-clock access to care, same-day or next-day appointments for in-person, and virtual care visits with zero copays.Everside aims to generate around 17% healthcare cost savings in three years and 31% in five years for its corporate members by leveraging a data-driven approach to care coordination.The company leverages data from past medical records, predictive analytics, and AI in the delivery of preventative care services.Founded in 2010 under the name Paladina Health, the company was rebranded in November 2020 as Everside Health following a merger between three primary care groups (Paladina, Activate Healthcare, and Healthstat). Furthermore, in February 2024, Everside Health merged with primary care provider Marathon Health to form a combined entity that would operate as Marathon Health, and, as of May 2024, the integration was ongoing.Key customers and partnershipPost-merger with Marathon Health, the combined entity would serve 2.5 million patients through over 680 clinics across 41 states.Funding and financialsThe company received its most recent investment in July 2022, amounting to USD 164 million in growth equity funding. The round was led by New Enterprise Associates (NEA). The funds were allocated toward growing its market presence and exploring opportunities for M&amp;A as well as to enhance and improve its product features. Additionally, the firm planned to expand its coverage of specialty care services aimed at individuals, employers, and union organizations.

Everside Health

Platforms offer a subscription-based or B2B-sponsored, evidence-based program for managing a specific long-term health condition.

DPCs offer value-based primary and preventive care services addressing whole-person (social, mental, physical) needs for a fixed monthly or annual fee paid by either the patient, insurance provider, or employer.

Companies offer B2B and D2C evidence-based treatments delivered via software programs to prevent and manage a variety of chronic conditions.

Tools that collect and analyze real-time patient data that supports healthcare providers with clinical decisions,  improves patient outcomes, and reduces medical errors.

Companies offer independent physician practices and hospitals with the tools (patient engagement, care coordination, administrative services) to help manage and improve clinical health outcomes of a defined group of individuals or large populations.

Platforms are used to track and gather patient health-related information via either a connected device or at-home test kits to detect the early onset of disease and identify any abnormalities in readings—but do not include a treatment plan.

To gather large amounts of real-time data for chronic care management, DTx, and patient monitoring

XR used by some startups for chronic pain management

Offers digital means of providing direct primary care, passive remote monitoring, chronic care management, etc.

AI/ML is used in predictive analytics, diagnostics tools, and population management

Offers tailored preventive interventions and treatments to the specific needs and characteristics of each individual

Twin Health is a healthcare technology company that has developed a patented "Whole Body Digital Twin" service to reverse, improve, and prevent chronic metabolic diseases such as type two diabetes, obesity, fatty liver, and dyslipidemia. Their solution is available through employer and health plan partners. The Whole Body Digital Twin is a dynamic model of an individual's unique metabolism, built using artificial intelligence and data from wearable sensors, clinical lab parameters, and self-reported preferences. It provides personalized, precise, and timely guidance across nutrition, sleep, activity, and stress through an easy-to-use app.
Twin Health's approach addresses the root cause of metabolic disorders – a dysfunctioning metabolism – by combining cutting-edge technology and advanced medical science. Their treatment program has demonstrated remarkable effectiveness, with notable outcomes including a 90% achievement of normal blood sugar levels within three months, 73% remission of type two diabetes after one year, and over 50% reduction in the risk of cardiovascular events, as validated by IIT Madras Research Park.
In a recent randomized controlled trial published in the American Association of Clinical Endocrinology, the intervention group showed a significant reduction in HbA1c (2.9% reduction from 9.0 to 6.1), higher elimination of diabetes medications (94% elimination), an average weight loss of 16.3 lbs, and normalization of baseline non-alcoholic fatty liver disease (NAFLD) in 64% of members. The company has expanded its reach, covering over 4 million lives through strategic employer and health plan partners.

Biostrap is a company that provides scalable and customizable biosensor-based precision health monitoring solutions. Their innovative wearable devices, such as the Biostrap Kairos launched in July 2023, offer advanced autonomic nervous system analysis and quantification of the sympathetic and parasympathetic branches through wrist-worn devices. Kairos utilizes a high-sensitivity CMOS optical sensor to capture raw photoplethysmography (PPG) data, enabling accurate computation of biometrics like heart rate, heart rate variability (HRV), beat-to-beat intervals, respiratory rate, and sleep-related parameters.
Biostrap's key differentiator lies in its commitment to delivering clinically reliable nervous system analysis through detailed and transparent biometric measurements. The Spot Check feature provides real-time visualization of the underlying PPG signal, signal quality, and R-R intervals, granting untethered access to every data point captured. This configurability and data integrity attracted clients like the National Police Wellbeing Service (NPWS) in the UK for their sleep, fatigue, and recovery program.
Kairos underwent extensive testing by HRV experts and achieved impressive accuracy levels, comparable to ECG chest straps. The launch marked Biostrap's pivot from the consumer wearable market to offering configurable hardware and software solutions for enterprise and research purposes.

Biostrap

Caeden is a wearable technology company that develops smart bracelets focused on promoting mindfulness and reducing stress. Their flagship product, the Sona smart bracelet, combines fashion and technology by integrating an advanced heart rate sensor into a genuine leather bracelet design. Launched in May 2016, the Sona retailed for USD 200 and offered a unique "Resonance" program, consisting of various breathing exercises tailored for different moments throughout the user's day.
The Sona aimed to provide a reprieve from the fast-paced city life by enabling users to start their day with a moment of zen, find calm and focus before important meetings, and unwind after workouts through concentrated breathing exercises. Caeden's founders, Nora Levinson and David Watkins, believed that regular use of the Resonance program could help build the user's resistance to stress, addressing a significant health issue faced by many.
Differentiating itself from step-tracking devices like Fitbit and smartwatches acting as smartphone extensions, the Sona positioned itself as a luxury item powered by technology designed to improve the wearer's overall quality of life through mindfulness. With its discreet design concealing the technology, the Sona aimed to offer mindfulness without drawing attention to the wearer's use of a device for that purpose.

Caeden

MyKronoz is a Swiss company that specializes in producing innovative hybrid smartwatches. Their flagship product, the ZeTime, was first launched in 2017 after a successful crowdfunding campaign on Kickstarter. The ZeTime features a unique design that combines traditional mechanical watch hands with a full-color touchscreen display, allowing it to function as both an analog watch and a smartwatch.
The watch offers activity tracking capabilities, including monitoring steps, calories burned, and sleep patterns using built-in sensors such as an accelerometer and optical heart rate monitor. It also provides smartwatch functionalities like displaying notifications, controlling music playback, and viewing incoming calls. The ZeTime's mechanical hands intelligently adjust their position to avoid obstructing the touchscreen display when interacting with the device.
One of the key advantages of the ZeTime is its impressive battery life. In watch mode, the battery can last up to 30 days on a single charge, while the smartwatch mode offers around 3-4 days of usage. The device also allows users to customize watch faces, either by selecting from pre-set options or creating their own designs using templates or personal photos.
The ZeTime received praise for its innovative concept and strong battery life. Some reviews, however, criticized its half-baked operating system, unresponsive touchscreen, and inconsistent activity tracking. Despite these drawbacks, MyKronoz's hybrid smartwatches garnered global recognition for their unique approach to wearable technology.

MyKronoz

Ringly is a company that produces fashionable smart jewelry, primarily rings and bracelets, aimed at the female market. Their devices are designed to discreetly notify wearers of incoming calls, messages, and app notifications through vibrations and LED lights. The rings are made from materials like 14k gold, sterling silver, and semi-precious gemstones like onyx, labradorite, and moonstone.
Ringly's core product is a smart ring that connects to the user's smartphone via Bluetooth. Through the Ringly app, users can customize which notifications trigger the ring's vibrations and colored LED lights. The app supports over 100 apps like calls, texts, emails, calendar alerts, and social media platforms. The rings are water-resistant and have a battery life of 2-3 days.
While technologically simple, Ringly's rings prioritize a fashionable and discreet design over advanced features. The idea is to provide a stylish alternative to smartwatches that seamlessly blends into the user's wardrobe and lifestyle without being obtrusive. Ringly has focused on creating fashionable jewelry pieces that also offer practical notification capabilities.

Ringly

Healbe Corporation is a technology company that develops wearable devices and associated software for health and wellness monitoring. The company's flagship product is the Healbe GoBe, a smart band that utilizes proprietary FLOW Technology to automatically track various body parameters. The GoBe device employs a combination of sensors, including an accelerometer, piezo pressure sensor, and impedance sensor, along with advanced algorithms to provide insights into users' overall health.
The GoBe smart band is designed to automatically measure calorie intake through the skin, eliminating the need for manual food logging. It also tracks calories burned, hydration levels, stress levels, sleep quality, heart rate, blood pressure, and physical activity. In November 2015, Healbe introduced automatic hydration level monitoring to the GoBe device, making it the first wearable to offer this feature without requiring manual input of fluid consumption.
Healbe's technology adapts to individual body characteristics, providing personalized insights and recommendations. The device monitors hydration levels continuously and alerts users when they need to drink more water. It also tracks emotional stress and helps users correlate it with their body's physical responses. The GoBe smart band measures energy expenditure throughout the day, including basal metabolism, regardless of physical activity levels.
The company's latest model, the GoBe3, incorporates additional features such as EDA-based Neuroactivity tracking and physiological stress estimation. It also offers improved sleep tracking capabilities, including detailed analysis of sleep phases and smart alarm functions designed to wake users during optimal sleep stages.
Healbe has developed a companion mobile application that synchronizes with the GoBe device in real-time, allowing users to view and analyze their data. The app provides detailed information on various health parameters and offers integration with Google Fit for a more comprehensive health data ecosystem.

Healbe

Wearable devices in form factors, such as wristwear and rings, designed to monitor and track various aspects of a person's physical activity, health, and wellness

Wearable entertainment devices designed primarily for entertainment and leisure purposes. These come in the form of hearables, wearable cameras, personalized smart devices, etc.

Apparel that incorporate electronic components, sensors, and connectivity features to provide functionalities beyond traditional clothing and accessories

Specialized wearable devices designed for use in industrial and work settings. These include safety wearables that come in the form of head-mounted devices, smart gloves, exoskeletons, etc.

Wearable devices, which are designed to monitor, collect, and transmit various health-related data, and wearable assistive devices. These come in the form of cardiac monitoring devices, glucose monitors, wearable pulse oximeters, hearing impairment aids, visual aids, etc.

Enhances the user experience by enabling language translation, contextual awareness, and personalized recommendations, making wearables more versatile and user-centric

Leveraging technology to collect data about the user's activities, preferences, and health metrics before using this information to provide personalized experiences

Industrial wearables contribute to increased efficiency, safety, and productivity in industrial settings by providing real-time data and connectivity solutions for workers and equipment

Empowers wearable devices to continuously improve and adapt to user preferences, offering personalized insights and recommendations based on user data

Enhances the functionality of wearables and allows users to access and interact with data through various devices and services in the broader IoT ecosystem

<div>

California digital health company, Twin Health, has garnered $50 million in investment from a funding round led by Temasek, joined by ICONIQ Growth, Sofina, Peak XV, and Helena. 
This funding will aid in the advancement of Twin Health's technology and clinical service solutions, with an objective of expanding its relevance across the US. 

</div>

Twin Health

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