Cigna Ventures

New technologies are opening up mental health services to previously overbooked and underserved populations.

Mental Health Tech

NOCD is a community-driven teletherapy provider for patients with obsessive compulsive disorder (OCD) through a mobile app. NOCD connects patients with exposure and response prevention (ERP)-trained therapists via video-based live consultations and offers personalized care plans for OCD treatment. The app helps users keep track of ERP exercises and also provides self-help tools, peer group access to its members, and the ability to receive 24/7 support in-between sessions from the therapist.The platform covers a range of OCD subtypes in areas such as contamination, hoarding, and relationships. The app was available in the US, Australia, Ontario (Canada), and the UK.&nbsp;A clinical study conducted by the Columbia University Medical Center on NOCD’s mobile app-integrated ERP treatment showed a reduction in OCD severity by an average of 40% in 8 weeks.&nbsp;Key customers and partnershipsAs of September 2024, the company had provided over 100,000 sessions monthly and had a network of over 300 OCD-specialized therapists. NOCD has partnered with major health insurers, including UnitedHealthcare, Aetna, Cigna, Humana, and Blue Cross Blue Shield, to provide in-network coverage. As of January 2023, over 130 million Americans had access to NOCD as a covered benefit through their insurance.

Valera is a B2B telepsychiatry platform that offers personalized digital mental health services using a team-based care approach that gives patients access to a care team consisting of in-network health coaches, therapists, counselors, social workers, nurse practitioners, and psychiatrists. Valera matches patients with an appropriate therapist after an initial consultation with a health coach and the patient’s care team creates a treatment plan.&nbsp;The company’s services include therapy, meditation, and medication for a range of mental health conditions from mild depression to severe schizophrenia. The company caters to members of insurance companies and employers with a mobile app that provides patients with access to their care team, video consultations, and a library of wellness and meditation programs. Valera claims that its treatment has led to depression improvement rates of more than 80%.Key customers and partnershipsValera Health has established partnerships with numerous health plans and healthcare systems, including Cigna, Humana, Blue Cross and Blue Shield of Vermont, and Point32Health. As of July 2023, the company's services were available to over 60 million lives across 10 states.&nbsp;In September 2023, the company partnered with BetterMynd to provide mental health services to college campuses across the US.

Alma is an electronic health record (EHR) and practice management platform for mental health providers. The platform enables therapists to manage various aspects of their practice, including insurance billing, scheduling, client referrals, and continuing education. Alma's EHR system allows providers to onboard new clients, document care, create evidence-based treatment plans, and track client progress over time using clinical assessments. In June 2024, Alma expanded its EHR suite by introducing AI-generated progress notes through a partnership with Upheal. This feature aims to reduce therapist burnout by automating the note-taking process, allowing providers to spend more time focusing on client care.Alma’s membership for its practice management tools is a monthly fee of USD 125. The company also provides free matching support to patients that use the platform.&nbsp;In <a href="https://sp-edge.com/updates/12631">August 2022</a>, Alma raised USD 130 million in a Series D round led by Thoma Bravo which valued the company at approximately USD 800 million. As of July 2021, the company also experienced a 13x YoY revenue growth compared to April 2020, while its insurance program grew 30x in the past 18 months.Key customers and partnershipsAs of September 2024, Alma’s network of therapists has grown to more than 21,000 members in all 50 US states.In addition to its partnership with Upheal to integrate AI-generated progress notes into its EHR system, it also partnered with Wiley to offer evidence-based treatment plans as part of its EHR functionality.

Octave is a teletherapy app that offers a range of evidence-based therapy options, including both in-person and virtual sessions. These therapy services cover various formats such as individual, group, and couples therapy. Octave follows a personalized approach by matching patients with suitable therapists and creating customized treatment plans to address their specific needs. In addition to therapy, Octave also provides coaching services aimed at enhancing individuals' mental and emotional well-being.Within three months of treatment, 76% of Octave clients with clinical depression and 74% of clients with clinical anxiety improved by at least one severity level. In May 2024, Octave expanded its services to 10 new states, bringing its total coverage to 17 states.Key customers and partnershipsOctave has established partnerships with several major insurance providers to offer in-network coverage for its services, including Aetna, Cigna Healthcare, Anthem, and Blue California. As of June 2023, Octave had served 18 million covered lives.

Membership-based, non-insurance healthcare companies helping maintain a steady state of well being.

Preventive Healthcare

9amHealth is a virtual diabetes care startup that caters to people with type 2 diabetes, hypertension, and hyperlipidemia by providing a personalized care plan with unlimited messaging access to a specialized medical team, in addition to prescriptions, medication home delivery, at-home lab testing services.9amHealth operates a subscription-based model where members are charged USD 20 per month for the online prescription and medical care services. Subscribers are charged an additional USD 5 per month for each added medication and USD 15 per month for at-home lab tests. The firm's services were available in 47 states and Washington DC.Funding and financialsIn <a href="https://sp-edge.com/updates/26906">February 2024</a>, the company raised USD 9.5 million in a Series A extension round led by The Cigna Group Ventures. The new funds were allocated toward the company’s growth strategy and product development.

RecoveryOne is a digital health company that provides a virtual physical therapy solution for individuals recovering from musculoskeletal (MSK) conditions. RecoveryOne’s MKS Care Solution is supported by a mobile app and includes clinically proven recovery plans, exercises, virtual coaching, and behavior change support. The company's approach involves a coordinated care team comprising licensed physical therapists and certified health coaches. The company claims that its model has improved patient outcomes up to 5%, reduced the need for surgery, and lowered payor costs.RecoveryOne’s proprietary Empowered MSK Care Solution app (i) connects members with a licensed physical therapist to create a personalized recovery plan (Pathway) based on member goals and lifestyle, (ii) records exercise progress and adjusts Pathway based on feedback, (iii) enables ongoing engagement with a certified health coach. Further, the platform incorporates an AI-powered sensorless computer vision technology called Motion Trainer, which provides real-time feedback and guidance to ensure patients perform exercises correctly.Key customers and partnershipsIn 2020, Cigna was the first health plan to introduce RecoveryOne’s MSK care as a consumer tool. And in January 2022, the two companies extended the partnership, making the solution available to Cigna’s employer clients with less than 500 employees.Further in February 2023, RecoveryOne partnered with MSU healthcare to integrate its virtual platform into the healthcare provider's network in Michigan. The company's platform is also included on Express Scripts' Digital Health Formulary.Funding and financialsThe company raised USD 33 million in Series C funding in September 2021 co-led by Cobalt Ventures and TELUS Ventures, which was used to fund the company’s expansion in payer and employer markets.

Zerigo Health (formerly Clarify Medical) provides at-home treatments for chronic skin conditions including psoriasis, vitiligo, and eczema, with narrowband ultraviolet B (NB-UVB) phototherapy.The Zerigo Health ecosystem includes an FDA-approved, handheld Smart UVB Light Therapy device controlled by a smartphone app that calculates and personalizes dosages based on each patient's response. The cloud-based system monitors treatment progress and adherence through secure data sharing. Furthermore, Zerigo's technology combined with personalized coaching from ZerigoCare Guides aims to improve treatment adherence and outcomes compared to traditional phototherapy methods requiring frequent in-office visits.Key customers and partnershipsIn September 2022, Evernorth launched a pilot program offering the Zerigo solution through its Digital Health Formulary. Also, in September 2022, Artemis Health, a benefits analytics platform, announced a partnership, enabling clients to evaluate and manage the Zerigo solution's impact on outcomes, quality of life, and costs using Artemis' Console analytics tool.Funding and financialsIn October 2021, the startup raised USD 43 million in a Series B funding round led by 7wireVentures, allocated towards expanding its operations and market reach, particularly in the B2B2C segment consisting of health plans and employer-sponsored health insurance.

Omada is a prevention-focused digital therapeutics startup that helps members achieve health goals through lifestyle changes. It offers four evidence-based, virtual prevention programs for managing hypertension, musculoskeletal (MSK) issues, prediabetes, and diabetes.Omada offers real-time data tracking through connected devices (such as wireless scales, blood pressure, and glucose monitors) and access to personalized coaching sessions via a mobile app as part of its prevention program. It also provides an online community of peers with similar health conditions to discuss challenges and provide support. In May 2021, Omada became the first fully-virtual healthcare provider to earn the National Committee for Quality Assurance’s Population Health Program Accreditation for its type 2 diabetes and type 2 diabetes + hypertension programs.Unlike its peers, Omada operates a performance-based business model where it charges clients an enrollment fee based on the number of users and a performance fee based on how much weight their employees lose. In May 2020, the company acquired virtual physical therapy startup Physera.Key customers and partnershipsAs of May 2024, Omada had more than 1 million members from more than 1,900 enterprise clients across all 50 US states. Its B2B employer and health plan client base include key clients such as American Eagle, Kaiser Permanente, Costco Wholesale, 3M, and Marvin. Additionally, the company has partnered with health systems and hospitals such as Intermountain Healthcare to provide its preventive programs as a covered benefit.In <a href="https://sp-edge.com/updates/15587">January 2023</a>, the company partnered with health service company Castell (a subsidiary of Intermountain Healthcare) to provide its diabetes programs to members from Intermountain Healthcare’s primary care providers in its Utah Medical Group. Further in <a href="https://sp-edge.com/updates/25245">January 2024</a>, the company partnered with Amazon to expand access to its cardiometabolic program.

More important now than ever, telehealth will long outlast the pandemic that drove its growth.

Telehealth

Cricket Health provides integrated nephrology and dialysis care to manage chronic kidney disease (CKD) and end-stage renal disease (ESRD). The company also triages CKD patients at stages 3b and beyond in order to provide stage-specific care using its StageSmart analytics tool.In <a href="https://www.fiercehealthcare.com/providers/interwell-health-finalizes-24b-kidney-care-merger-combine-tech-value-based-care#:~:text=Providers-,InterWell%20Health%20finalizes%20%242.4B%20kidney%20care%20merger,tech%2C%20value%2Dbased%20care%20capabilities&amp;text=InterWell%20Health%20completed%20a%20three,costs%20under%20management%20by%202025.">August 2022</a>, Fresenius Health, Cricket Health, and InterWell Health merged into a single kidney care provider that focuses on the early stages of kidney disease. The value of the merged entity was estimated to be USD 2.4 billion.The merged entity operates independently under the InterWell Health brand and brings together Fresenius Health’s global dialysis operations, InterWell Health’s network of more than 1,600 nephrologists, and Cricket Health’s proprietary machine learning predictive analytics model for risk stratification and its patient engagement platform. The new entity utilizes its data analytics capabilities and patient engagement platform to identify high-risk patients and deliver in-person and virtual clinical support.

Babyscripts is a virtual care platform focused on managing obstetrics and improving maternal health outcomes. The company's core product is a mobile app called Babyscripts myJourney, which provides gestational age-appropriate educational content and appointment reminders to pregnant and postpartum patients. Through IoT devices, Babyscripts enables obstetricians to remotely monitor up to <a href="https://babyscripts.com/maternity-care-program">93</a>% of pregnancies, allowing earlier risk detection and intervention. The platform is designed to supplement in-person prenatal care visits, optimize the visit schedule, and free up provider time to focus on higher-risk patients.Babyscripts' solution also includes remote patient monitoring for blood pressure and weight tracking, with automated alerts for concerning readings. Additionally, the app delivers daily pregnancy-related tasks and information approved by the patient's healthcare provider. The company's technology aims to improve access to care, particularly for underserved populations, and reduce maternal mortality and morbidity rates.Key customers and partnershipsBabyscripts has formed partnerships with several healthcare providers and systems across the US.In <a href="https://www.fiercehealthcare.com/digital-health/babyscripts-teams-lyft-provide-transportation-maternal-health-services">May 2024</a>, Lyft, a ride-hailing service, partnered with the company to provide users with transportation to maternal health services. Through the partnership, Lyft Healthcare began offering sponsored rides for people who are pregnant or postpartum and face barriers to transportation.In <a href="https://www.prnewswire.com/news-releases/memorial-hermann-announces-partnership-with-leading-virtual-maternity-care-platform-babyscripts-301834735.html">May 2023</a>, Memorial Hermann Health System announced a partnership with Babyscripts to provide virtual maternity care to their patients.&nbsp;In <a href="https://www.prweb.com/releases/leading-pregnancy-app-babyscripts-announces-partnership-with-nuvo-group-to-deliver-first-of-its-kind-comprehensive-remote-pregnancy-care-solution-817889656.html#">October 2021</a>, the company partnered with the Nuvo Group, a company commercializing an FDA-cleared remote pregnancy monitoring platform, to deliver a comprehensive remote pregnancy care solution. Through this partnership, Nuvo began offering non-stress tests, within Babyscripts' commercial ecosystem, with the goal of advancing pregnancy care delivery for providers and their patients, particularly those at high risk of complications.

Buoy Health offers an AI-powered symptom checker to help individuals and patients navigate their health concerns by providing personalized clinical guidance. Buoy's platform assesses users’ symptoms and suggests appropriate care options, ranging from telemedicine to primary care and behavioral health resources. The platform aims to reduce unnecessary healthcare visits by directing users to the right level of care by helping patients connect with healthcare providers covered by their health insurance.The company is able to navigate users based on a variety of symptoms relating to several areas, including back and extremities, chest and breast, digestive and genitals, head and face, behavioral, neurological, skin conditions, sleep, and systemic. Based on the user’s patients, the platform can coordinate care for users with regard to a range of healthcare and healthcare-related offerings, including doctors and providers, lab testing, nutrition and vitamins, pharmacy services, skincare products, supplements, and weight management practices and medication. The platform also has community features as well as curated educational material.Key customers and partnershipsIn <a href="https://www.prnewswire.com/news-releases/buoy-health-selected-as-preferred-partner-in-ai-enhanced-symptom-checker-digital-front-door-category-by-consortium-health-plans-301112518.html">August 2020</a>, the company partnered with Consortium Health Plans to be a preferred partner. Through the partnership, Consortium's Clinical Innovation and Partnerships team began recommending Buoy as the AI-Enhanced Digital Front Door for its member plans for patient evaluations when serving their 25 million national account members.In <a href="https://healthcare-digital.com/technology-and-ai/buoy-health-leveraging-ai-partnership-cvs-health">May 2020</a>, the company partnered with CVS Health subsidiary MinuteClinic to provide users with access to convenient, accessible, and affordable care at any of MinuteClinic’s locations across the US.

AristaMD provides a software platform called eConsults, which helps healthcare providers carry out specialist consultations and provide instant referrals to improve patient care transitions. The company claims that its white label platform helps healthcare providers develop specialist-backed treatment plans within 24 hours, instead of having patients wait weeks to consult with specialists. The platform includes features such as the ability to select specialists based on insurance coverage, the ability to integrate into existing workflows, and EHR integration and interoperability. <a href="https://www.aristamd.com/">The company also claims that its HIPAA-compliant platform can reduce routine referrals by 70%.</a>AristaMD serves payors, health systems, ACOs, and primary care clinics, enhancing patient experiences and outcomes.In <a href="https://www.aristamd.com/press/aristamd-and-sitka-form-single-company/">November 2023</a>, the company merged with Sitka, an asynchronous peer-to-peer virtual consultation provider, to form a single healthcare video consultation provider. The merger was carried out to help AristaMD offer more ways for primary care providers to expand their scope of services. The merged entity also combined Sitka's group of virtual specialty providers with AristaMD’s referral nurse navigation and access to referral management services to simplify access to healthcare services for Medicare, Medicaid, and other health plan members across the US. Post-merger, Kelsey Mellard, founder and CEO of Sitka, became the new president of AristaMD, while Dr. Julia Jezmir, previously the chief medical officer for Sitka, was brought on as chief medical officer for AristaMD.In <a href="https://www.aristamd.com/press/aristamd-names-keith-pinter-chief-executive-officer-as-company-continues-longitudinal-care-management-in-collaboration-with-primary-care/">May 2024</a> AristaMD announced that Keith Pinter, a healthcare veteran, was appointed CEO. Brooke LeVasseur, the former CEO, transitioned into the role of strategic advisor for the company. The company noted that Keith Pinter would focus particularly on accelerating clinical efficacy for patients with high-cost, high-impact conditions.Key customers and partnershipsIn <a href="https://www.aristamd.com/press/ochin-partners-with-econsult-vendor-aristamd-to-expand-econsult-services/">April 2021</a>, AristaMD partnered with OCHIN, a national nonprofit health IT organization, to expand ‘eConsult’ services for nearly six million underserved patients across the US. Through the partnership, primary care providers in the OCHIN network gained access to additional resources for more rapid and integrated virtual health care delivery through AristaMD’s platform. Additionally, OCHIN launched its eConsults to AristaMD's network, directly giving providers more options for collaboration with specialists.AristaMD partnered with the University of Colorado School of Medicine in <a href="https://www.aristamd.com/press/cu-school-of-medicine-econsults/">September 2020</a> to expand eConsults to a network of community providers. Through the partnership, AristaMD enabled healthcare providers using its platform to consult with specialists from the University of Colorado School of Medicine.

Simplifying healthcare administration with intuitive tech tools

Hospital Management

Arcadia is a healthcare technology company that provides a comprehensive data platform for healthcare providers and payers. The company's flagship product, Arcadia Analytics, serves as a cornerstone for managing value-based care contracts and population health initiatives. Arcadia's platform aggregates and analyzes data from various sources, including clinical EHRs, claims data, social determinants of health, pharmacy records, and ADT feeds, to provide actionable insights for healthcare organizations. The platform offers flexibility and accuracy, enabling users to generate actionable data shared across networks. Arcadia Analytics features a user-friendly web portal and deep data mining capabilities, allowing healthcare professionals to access essential tools for population health management. In December 2023, Arcadia sold its managed service organization and value-based care service division to Guidehealth, a value-based care enablement startup. However, Arcadia continues to partner with Guidehealth, providing its data analytics platform to power the newly acquired offering.
Key customers and partnerships
Arcadia's platform is utilized by a wide range of healthcare organizations, including providers, payers, and innovative organizations seeking to improve population health management. In October 2022, the company was recognized as one of the largest health tech companies in Massachusetts by the Boston Business Journal. Arcadia has established partnerships with various healthcare entities, including a collaboration announced in December 2023 with Guidehealth to leverage Arcadia's data analytics platform. The company's solutions have been implemented by multiple teams within healthcare organizations, demonstrating its wide-reaching impact in the industry.

AristaMD offers an eConsult and referral management platform that facilitates electronic consultations between primary care physicians (PCPs) and specialists. The platform enables organizations to conduct eConsults (electronic physician-to-physician consultations), schedule peer-to-peer reviews for insurance authorization, and streamline physician referral selection and routing processes. The eConsult feature allows PCPs to request guidance from a panel of specialists on specific patient cases, receiving a response within 24 hours. Over 73% of eConsults result in PCPs treating patients immediately without requiring a referral, and over 30% lead to new diagnoses as of April 2023.
When a face-to-face specialist visit is necessary, AristaMD's platform matches patients with appropriate in-network specialists based on factors like insurance coverage, location, and subspecialty. Referrals are ordered electronically, eliminating the need for phone calls or fax machines. The platform also notifies patients automatically when referrals are sent, sends appointment reminders, gathers medical history, and communicates diagnoses, treatment plans, and follow-up recommendations back to referring physicians.
AristaMD's eConsult platform was launched early in the Covid-19 pandemic to prevent delays in accessing specialty care. The company reported in April 2023 that its platform reduces unnecessary referrals by 70%, allowing patients to receive timely, specialist-guided treatment in primary care settings. This alleviates inconvenience, stress, and out-of-pocket expenses while improving patient satisfaction. In October 2019, AristaMD partnered with Corstrata to offer consultations with board-certified wound and ostomy specialists through its platform.

A concentration of wealth and a willingness to adopt age-in-place technologies present new opportunities.

Age Tech

Monogram Health provides access to in-home and virtual physician and nurse practitioner visits for patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD).Monogram’s managed services platform establishes partnerships with health plans (e.g., Humana, WellCare Health Plans) to bring disease management, utilization management, and medication therapy management to its patients. Monogram’s team of nurses, nephrologists, dieticians, pharmacists, and social workers coordinate with the patient’s care network to manage their care requirements. The company uses technology to remotely monitor patient biometrics and predictive analytics to identify patients at high risk of progression, medication errors, and care gaps.According to the company, it has tripled the rates of home dialysis to 28% (national average 10%), doubled planned dialysis transitions to 45% (national average 20%), and reduced readmission rates by half to 18% (national average 35%).As of January 2024, the company noted that company’s plan partners, which include Cigna, Humana, Aetna, and the US Department of Veterans Affairs, have seen significant improvements, including doubled dialysis transitions and reduced readmission rates.Key customers and partnershipsIn March 2021, Monogram partnered with Medicare Advantage (MA), a healthcare and insurance coverage plan under Cigna, a multinational US-based insurance company. The partnership entails access to Cigna’s customers in 18 states, including Florida, Texas, Pennsylvania, Illinois, North Carolina, South Carolina, New Jersey, Delaware, Maryland, Missouri, Kansas, Colorado, and the District of Columbia.In January 2024, Monogram partnered with health insurer Blue Cross Blue Shield of Arizona (AZ Blue), to enhance kidney disease care. Through the partnership, Monogram extended its in-home care services and benefit management services to AZ Blue's nearly two million members. Monogram also assumed financial responsibility for some AZ Blue members with kidney disease, giving patients access to a wide range of services, including complex disease management and medication therapy management.Most recently, in June 2024, the company partnered with Memorial Hermann Health System, a major not-for-profit health system in Southeast Texas, to improve outcomes for patients diagnosed with polychronic conditions. The partnership aimed to leverage the organizations' clinical expertise to deliver high-quality, in-home care to patients in Southeast Texas living with complex chronic conditions, particularly chronic kidney disease (CKD) and end-stage kidney disease (ESKD). Monogram's evidence-based care model and benefit management services was combined with Memorial Hermann's medical staff and physicians to slow the progression of CKD and ESKD, improve patient outcomes, and enhance quality of life while reducing medical costs.

Automation in clinical diagnostics to improve speed and accuracy in patient diagnosis and treatment.

Clinical Decision Support Systems

Cleerly is a digital healthcare company that has developed an AI-enabled platform to help physicians precisely identify, define, and treat heart disease at its earliest stages when it is most treatable. The company's platform leverages non-invasive coronary computed tomography angiography (CCTA) imaging and AI-powered, FDA-cleared solutions to perform comprehensive coronary artery phenotyping. This technology is based on millions of annotated lab images used to build over two dozen proprietary algorithms capable of quantifying and characterizing the presence, extent, severity, and type of coronary artery disease (CAD) and other cardiovascular disorders.
Cleerly's advanced machine learning and AI algorithms enable providers to perform comprehensive assessments of a patient's CCTA, studying each artery and branch to show the patient's risk of CAD in just seven minutes. The diagnostic tools and reporting solutions are tailored to all stakeholders in the heart care pathway, including patients, and the personalized reporting allows providers to deliver precision treatment plans.
In July 2022, Cleerly secured a USD 223 million Series C funding round, bringing its total funding raised to USD 279 million. The company has received two FDA clearances for its products in 2019 and 2020. Cleerly announced positive data from the CERTAIN Study in February 2024, demonstrating the independent and strong incremental impact of its products in changing clinical decision-making and patient management in over 57% of cases compared to conventional CCTA interpretation.

Using real-time data to create dynamic virtual representations of the real world

Digital Twin

Aitia is an AI-enabled biotechnology company that utilizes causal AI and Gemini Digital Twins to discover and develop new drugs in neurodegenerative diseases and oncology. The company's technology combines multi-omic patient data, high-performance computing, and causal AI to create virtual models of diseases. These Gemini Digital Twins are reverse-engineered from genetic, multi-omic, and clinical data from patients to reveal how genes, proteins, and molecules interact within cells and tissues to drive clinical outcomes. The platform enables researchers to rapidly test billions of experiments, such as gene and protein knockdowns or drug candidate applications, in a human patient context rather than using traditional animal models or cell cultures.
The company's approach centers on two key innovations: causal AI, which identifies genetic and molecular changes driving diseases and patient responses to therapies, and Gemini Digital Twins, which allow for high-throughput virtual experiments to discover drug candidates with higher potential for clinical trial success. Aitia's technology has been deployed across multiple therapeutic areas including oncology, neurodegeneration, cardiometabolic disorders, and immunology.
Key customers and partnerships
Aitia has established several strategic partnerships with major pharmaceutical companies. The company expanded its collaboration with Servier in October 2024 to tackle gliomas, marking their fourth research area partnership since 2022, which includes programs in Multiple Myeloma, pancreatic cancer, and Parkinson's disease. In September 2024, Aitia entered into a partnership with Orion Corporation for cancer drug discovery. The company also formed a strategic agreement with Charles River Laboratories in November 2023 for neurodegenerative diseases and oncology research, which included the co-development of patient-derived xenograft Digital Twins for oncology research.

Redefining hospital care with the comfort of home

Hospital-at-Home

Monogram Health is a Nashville, Tennessee-based company that provides specialized in-home care and benefit management services for patients living with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Founded with a focus on health equity, the company deploys an innovative care delivery model that combines technology-driven solutions with evidence-based clinical services to transform the way healthcare is delivered for those with kidney disease and comorbid metabolic disorders.
Monogram's approach includes complex case and disease management, utilization management, and medication therapy management. The company's care teams, consisting of physicians, nurse practitioners, registered nurses, social workers, pharmacists, and care managers, provide personalized care plans and in-home visits to patients. Monogram utilizes proprietary, evidence-based protocols and technology to actively manage patients' kidney disease and a wide range of acute and chronic conditions.
As of January 2023, Monogram operated in nearly 4,000 US cities across 34 states, serving patients through value-based partnerships with leading health plans and risk-bearing providers. The company's model has been shown to improve patient outcomes and quality of life while reducing medical costs across the healthcare continuum. In October 2022, Monogram expanded its services to include most of Humana's Medicare Advantage HMO and PPO members in Tennessee, Alabama, Louisiana, and Mississippi.
Key customers and partnerships
The company has formed a value-based care agreement with Humana, announced in October 2022, to offer in-home kidney care to Humana's Medicare Advantage HMO and PPO plan members in Tennessee, Alabama, Mississippi, and Louisiana. This partnership aims to provide eligible members with access to Monogram's specialized offerings, including in-home primary and specialty care, medication management, dialysis and transplant coordination, and social services.

9amHealth offers complete cardiometabolic care—a first-of-its-kind, whole-body approach to preventing and treating diabetes, obesity, high cholesterol, and hypertension. We partner with employers, PBMs, and health plans to provide effective health benefits for those living with chronic conditions. 9am's members receive personalized care plans, prescription delivery, at-home lab tests, and unlimited specialist access. 9amHealth was founded in 2021 by the team behind mySugr and is backed by Cigna Ventures, 7Wire Ventures, Human Capital, Founders Fund, and Define Ventures. More at www.join9am.com.

Octave provides mental health care that’s both accessible to people and sustainable for providers. It partners with clients to develop personalized care plans to best suit the individual's needs. Grounded in science, Octave enables clients to experience profound change that is just as measurable as it is meaningful.

NOCD is an online OCD therapy platform that helps people with OCD get better and then stay better. With NOCD, users can have face-to-face video therapy sessions with licensed therapists that specialize in OCD, as well as get 24/7 support between sessions from self-help tools and peer communities.

Monogram Health is a value-based specialty provider of in-home evidence-based care and benefit management services to patients suffering from polychronic conditions such as chronic kidney disease and end-stage renal disease. To transform the way health care is delivered for those with polychronic conditions, the company uses an innovative in-home care delivery model and a technology-driven array of evidence-based clinical services, such as complex case and disease management, utilization management, and medication therapy management. This innovative care model has been shown to improve patient outcomes and quality of life while lowering medical costs across the healthcare continuum. Monogram Health, based in Nashville, Tennessee, has numerous value-based partnerships with leading health plans and risk-bearing providers to care for patients across all insurance products and 34 states.

Founded in 2015, Valera Health combines digital technology and data science with a human touch to deliver in-class clinical services to patients with mild to severe mental health conditions including depression to schizophrenia. With a focus on outcomes and servicing hard-to-reach populations, Valera Health is redefining high-performing mental healthcare.

Alma is a membership-based network for mental health care providers that aims to improve access to high-quality, affordable mental health care. Its platform enables providers to accept insurance and also provides a member directory, client-matching service, scheduling, and billing functions, as well as education, training, and a community for support.

Cleerly is a healthcare company whose mission is to create digital care pathways to prevent heart attacks. The company develops a new standard for coronary artery disease by integrating quality clinical science with the latest-generation AI, in order to offer actionable clinical insights to every stakeholder in the heart care pathway. Through these data-driven solutions, the company aims to provide a comprehensive solution for cardiovascular disease evaluation that offers value to the healthcare system and improves heart health for patients at risk of heart attacks.

Flume Health makes self-insured health plans affordable and easy to use. They do this by combining the incredible best customer support that they would never expect from their health plan administrator, along with a new payments technology that allows its members to see the same providers for 20-40% less than traditional network rates. The company was founded in 2018  and is headquartered in New York.

Bright Health Group is a health insurance company that delivers affordable healthcare to aging and underserved populations. Bright Health aims to improve the healthcare experience by leveraging technology to streamline operations and enhance member engagement. They focus on building partnerships with health systems and care providers to create integrated healthcare networks. By forming these partnerships, Bright Health seeks to offer its members a more personalized and coordinated healthcare experience. The company differentiates itself by utilizing data analytics and digital tools to help both its members and healthcare providers make more informed decisions about healthcare. They strive to simplify the complexities of health insurance and improve access to quality care for their customers.

Babyscripts’ three-tiered approach to virtual maternity care allows providers to deliver risk-specific care to pregnant mothers at any time, in any place. The first tier consists of a digital education layer delivered via a mobile app, with daily gestational-age and practice-specific, customizable content extending through one year postpartum to engage and empower pregnant mothers through trusted resources. The second tier enables virtual management of pregnant patients through the addition of remote monitoring. Depending on the risk, patients are provided with medical devices (like a bluetooth-enabled blood pressure cuff) to monitor for elevated risk, alerting the provider through a unique trigger alert system to enable risk management and intervention. This smart end-to-end management of patients enables the provider to transition care outside of the clinic and address problems of access, allowing them to automate a majority of their patient care while more effectively allocating time and resources to higher-risk patients. The third tier brings the insurer into the equation in a unique collaboration between the care team and payer, solving some of the structural issues of care coordination and access to care, improving outcomes while reducing cost.

Clarify Medical is innovating a well-established treatment, UVB therapy, to become easier, more convenient, more empowering, and more connected for psoriasis, eczema and vitiligo patients. The company also focused on developing innovative technology, products, and services that improve care for people with chronic skin conditions. Clarify Medical indicated for the localized phototherapeutic treatment of dermatologic conditions such as psoriasis, vitiligo, atopic dermatitis (eczema), seborrheic dermatitis, and leukoderma on all skin types (I-VI). It is the first and only connected phototherapy system that uses an app on the patient’s own smartphone (iOS or Android) to manage the dose, frequency, and duration of UVB light therapy, helping to ensure that patients receive the proper doses recommended by the American Academy of Dermatology and Vitiligo Working Group.  The treatment regimen is prescribed by the patient’s physician but monitored and controlled by the Clarify System, enabling patients to administer treatment with clinical precision in the convenience of their homes. The connected system monitors dosing, adherence, compliance, patient progress, and satisfaction.

RecoveryOne is an innovator in mHealth solutions for patients recovering from orthopedic injuries. The company provides personalized programs that combine digital therapy and live coaching to reduce costs, accelerate recovery, and drive patient satisfaction. RecoveryOne was founded in 2014 and is headquartered in Walnut Creek, California.

Cricket Health is a specialty kidney care provider of integrated nephrology and dialysis care for people with Chronic Kidney Disease (CKD) and End Stage Renal Disease (ESRD).  Cricket Health delivers world-class, technology-enabled multidisciplinary care both in-person and virtually to achieve the best outcomes possible for patients and the best value for partners, keeping patients healthy and out of the hospital, accelerating access to transplant, and increasing home dialysis adoption.  We are committed to aligning the success of our company with those of our partners and the patients whom we serve.  Learn more at www.crickethealth.com and follow us @crickethealth

MedAvail focuses on the discovery, development, and commercialization of advanced nutrition products to improve muscle health and performance.

Buoy provides a personalized all-in-one platform to help guide consumers back to health. Whether it's chatting about symptoms with Buoy Assistant to get help in the moment of sickness or researching benefits through Buoy Dashboard, Buoy is available 24/7 to help make self-diagnosis and navigating the healthcare system simple and easy. For employers, Buoy can be custom configured to surface benefits information and wellness programs, guide employees to in-network providers, and fully integrate with other health portals.  The company was founded in 2014 and is headquartered in Boston, Massachusetts.

Datavant is a data logistics company for healthcare whose products and solutions enable organizations to move and connect data securely. Datavant has a network of networks consisting of thousands of organizations, more than 70,000 hospitals and clinics, 70% of the 100 largest health systems, and an ecosystem of 500+ real-world data partners. To learn more about Datavant, visit datavant.com.

Ginger is a telemental health provider delivering evidence-based behavioral health coaching, therapy, and psychiatry from a smartphone. Ginger's on-demand system brings together behavioral health coaches, therapists, and psychiatrists, who work as a team to deliver personalized care, right through your smartphone. The app provides members with access to the support they need within seconds, 24/7, 365 days a year. Millions of people have access to Ginger through leading employers, health plans, and its network of partners.

AristaMD is a healthcare company that features a software platform that helps hospitals and practitioners on improving patient outcomes. It also offers a solution that enables primary care providers to ask questions about patients that they would otherwise refer out and transmit patient clinical notes, history, lab results and images to collaborate on care plans with a panel of on-call, board-certified specialists, all within a matter of hours. The company was founded in 2013 and headquartered in La Jolla, California.

Arcadia is dedicated to happier, healthier days for all. We transform diverse data into a unified fabric for health. Our platform delivers actionable insights for our customers to advance care and research, drive strategic growth, and achieve financial success.

Aitia is the leader in the application of Causal AI and Digital Twins to discover the next generation of breakthrough drugs. By leveraging the convergence of multi-omic patient data, high-performance computing, and causal learning and AI, Aitia is revealing the hidden biological mechanisms of disease to create Digital Twins of disease in oncology, neurodegenerative disorders, and immunology. Gemini Digital Twins are being used today to discover novel therapies and accelerate R&D in multiple myeloma, prostate cancer, Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease, with several more in development. Aitia’s partners include seven of the top ten pharmaceutical companies, leading academic research and medical centers, medical societies, leading multi-omic data companies, and patient advocacy groups globally.

Omada Health is a digital care company that offers innovative and clinically effective digital health programs to empower individuals to engage in their health and lead healthier lives. The program is personalized to meet each participant’s unique needs as they evolve, ranging from diabetes prevention, type 2 diabetes management, hypertension, behavioral health, and musculoskeletal issues. Omada combines professional health coaching, connected health devices, real-time data, and personalized feedback to deliver clinically meaningful results. The company is the largest CDC-recognized provider of the National Diabetes Prevention Program.

Cigna Ventures is the arm venture of Cigna, that accelerate growth of start ups in health care industry. The company's mission is to accelerate Cigna’s ability to improve the health, well-being and sense of security of the people we serve by partnering with and investing in innovative companies, and delivering differentiated value in the marketplace. It focuses on harnessing transformative ideas in insights and analytics; digital health and retail; and care delivery and management.

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